1-[2-(4-乙基苯基)乙基]哌啶 | 730912-76-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-[2-(4-乙基苯基)乙基]哌啶
• 英文名称: 1-[2-(4-Ethylphenyl)ethyl]piperidine
• CAS: 730912-76-2
• 化学式: C₁₅H₂₃N
• mdl: MFCD28157911
• 分子量: 217.35
• InChiKey: CVCRDICIXHUNKF-UHFFFAOYSA-N

物化性质

• 沸点：
  308.4±11.0 °C(Predicted)
• 密度：
  0.950±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• ARYL-SUBSTITUTED DIHYDROQUINOLINONES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
  申请人：NEOMED Institute

  公开号：US20200299262A1

  公开（公告）日：2020-09-24

  This application relates to aryl-substituted dihydroquinolinones of formula (I), compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to aryl-substituted dihydroquinolinones and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.
• USRE46511E1
  申请人：——

  公开号：USRE46511E1

  公开（公告）日：2017-08-15