光气 、 5-氟-2,4-二甲氧基苯胺 以
乙酸乙酯 为溶剂,
反应 1.5h,
以to provide 1.74 g (100% yield) of 1-fluoro-5-isocyanato-2,4-dimethoxybenzene as a solid的产率得到1-氟-5-异氰酸-2,4-二甲氧基苯
参考文献:
名称:
Positive allosteric modulators of the nicotinic acetylcholine receptor
[EN] POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR<br/>[FR] MODULATEURS ALLOSTERIQUES POSITIFS DE RECEPTEUR NICOTINIQUE DE L'ACETYLCHOLINE
申请人:UPJOHN CO
公开号:WO2003093250A2
公开(公告)日:2003-11-13
The invention provides compounds of Formula I: (1) these compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which α7 nAChR is known to be involved.
Positive allosteric modulators of the nicotinic acetylcholine receptor
申请人:——
公开号:US20030236287A1
公开(公告)日:2003-12-25
The invention provides compounds of Formula I:
1
These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which &agr;7 nAChR is known to be involved.