1-氨基十二烷-2-醇 | 4054-54-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 1-氨基十二烷-2-醇
• 英文名称: 1-aminododecan-2-ol
• 英文别名: 1-amino-dodecan-2-ol；2-hydroxy-dodecylamine；2-Hydroxy-dodecylamin
• CAS: 4054-54-0
• 化学式: C₁₂H₂₇NO
• 分子量: 201.352
• InChiKey: VIXJLJIOHUCFAI-UHFFFAOYSA-N

物化性质

• 沸点：
  130-131 °C(Press: 2 Torr)
• 密度：
  0.882±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-氨基十二烷-2-醇 在 三乙胺 作用下， 生成 N-(2-oxododecyl)benzamide
  参考文献：
  名称：

  A versatile approach to 3-alkyl and 2,3-dialkylpyrroles

  摘要：

  A route is described towards N-benzoyl-3-alkyl and N-benzoyl-2,3-dialkyl pyrroles from alpha -amido-ketones via an intramolecular Wittig reaction to afford 4-phenylthio-3-pyrrolines which are then oxidised to the corresponding sulphones and aromatised by treatment with potassium t-butoxide. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01591-4
• 作为产物：
  描述：

  1-azido-2-hydroxydodecane 在 palladium on activated charcoal 氢气 作用下， 以 乙醇 为溶剂， 反应 48.0h， 以70%的产率得到1-氨基十二烷-2-醇
  参考文献：
  名称：

  烷基化氨基醇及其糖基化衍生物的制备及其抗结核活性。

  摘要：

  合成了一系列的N-和C-烷基化的氨基醇及其受保护的吡喃半乳糖基衍生物，并评估了其抗结核活性。这些化合物中的五种显示出良好的活性，MIC低于12.5mug / mL。碳水化合物的存在对抗菌活性有轻微的影响。

  DOI：

  10.1016/j.bmc.2007.08.045

文献信息

• Preparation and antitubercular activities of alkylated amino alcohols and their glycosylated derivatives
  作者：Aline F. Taveira、Mireille Le Hyaric、Elaine F.C. Reis、Débora P. Araújo、Ana Paula Ferreira、Maria Aparecida de Souza、Lívia L. Alves、Maria C.S. Lourenço、Felipe Rodrigues C. Vicente、Mauro V. de Almeida

  DOI：10.1016/j.bmc.2007.08.045

  日期：2007.12

  A series of N- and C-alkylated amino alcohols and of their protected galactopyranosyl derivatives was synthesized and evaluated for antitubercular activity. Five of these compounds displayed good activity, with a MIC below 12.5mug/mL. The presence of the carbohydrate slightly affected the antibacterial activity.

  合成了一系列的N-和C-烷基化的氨基醇及其受保护的吡喃半乳糖基衍生物，并评估了其抗结核活性。这些化合物中的五种显示出良好的活性，MIC低于12.5mug / mL。碳水化合物的存在对抗菌活性有轻微的影响。
• Lubricant Composition for Fluid Dynamic Bearing
  申请人：Okada Tahei

  公开号：US20070281873A1

  公开（公告）日：2007-12-06

  A lubricating oil composition for fluid dynamic bearings which comprises 50 to 100% by mass of an ether compound comprising at least one ether bond and having 11 to 34 carbon atoms as the base oil and has a kinematic viscosity of at least 2.2 mm 2 /s at 100° C. is provided. The composition has excellent viscosity characteristics such as excellent fluidity at low temperatures and a small decrease in the viscosity in a high temperature range, exhibits lower evaporability, excellent energy saving property and excellent heat stability and is advantageously used for compact fluid dynamic bearings used under rotation at a high speed.

  提供一种用于流体动力轴承的润滑油组合物，其包括质量百分比为50至100%的醚化合物作为基础油，该醚化合物至少包含一个醚键，碳原子数为11至34个，并且在100°C时具有至少2.2 mm²/s的运动黏度。该组合物具有出色的黏度特性，如低温下的出色流动性和高温范围内黏度的小幅降低，表现出较低的挥发性，出色的节能性能和优异的热稳定性，适用于在高速旋转下使用的紧凑型流体动力轴承。
• Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition
  申请人：Sato Haruhito

  公开号：US20080146469A1

  公开（公告）日：2008-06-19

  The present invention provides a process for producing a saturated aliphatic hydrocarbon prepared using an α-olefin as a raw material and represented by the general formula (1), including the steps of: (I) producing a vinylidene olefin by dimerizing the α-olefin in the presence of a metallocene complex catalyst; (II) further dimerizing the vinylidene olefin in the presence of an acid catalyst; and (III) hydrogenating the obtained dimer. Further, there are provided a lubricant composition containing the saturated aliphatic hydrocarbon compound produced by the above process, a bearing oil consisting of the lubricant composition, and making use of the same, a bearing and gyral equipment. The saturated aliphatic hydrocarbon compounds produced by the process of the present invention have low-temperature fluidity, exhibiting low evaporativity, and excellent in thermal stability and oxidation stability. Thus, the saturated aliphatic hydrocarbon compounds are suitable for use as, for example, a base oil of lubricant composition for hydraulic pressure, turbine, working machine, bearing, gear, metal-working, etc.

  本发明提供了一种生产饱和脂肪族碳氢化合物的方法，该方法使用α-烯烃作为原料，并由一般公式（1）表示，其中包括以下步骤：（I）在金属茂络合物催化剂的存在下通过二聚化α-烯烃来生产乙烯基烯烃；（II）在酸催化剂的存在下进一步二聚化乙烯基烯烃；（III）对所得到的二聚体进行加氢。此外，还提供了一种润滑剂组合物，其中包含以上方法生产的饱和脂肪族碳氢化合物，一种由润滑剂组合物组成的轴承油，以及利用该油的轴承和陀螺设备。本发明所述的饱和脂肪族碳氢化合物具有低温流动性，表现出低蒸发性，并且在热稳定性和氧化稳定性方面表现优异。因此，该饱和脂肪族碳氢化合物适用于用作液压、涡轮、工作机、轴承、齿轮、金属加工等润滑剂组合物的基础油。
• LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE
  申请人：Yamada Ryou

  公开号：US20090181872A1

  公开（公告）日：2009-07-16

  A lubricating oil composition for internal combustion engines comprising a base oil containing at least one component selected from an α-olefin oligomer having 16 to 40 carbon atoms obtained by oligomerizing α-olefin(s) having 2 to 20 carbon atoms using a metallocene catalyst, and the hydrogenated derivative thereof; an α-olefin oligomer having 16 to 40 carbon atoms derived from an α-olefin dimer obtained using a metallocene catalyst, and the hydrogenated derivative thereof; and the like. The lubricating oil composition has an excellent low-temperature fluidity, a low evaporativity, and a good oxidation stability.

  一种用于内燃机的润滑油组合物，包括一种基础油，该基础油含有至少一种组分，所述组分是通过使用金属茂催化剂将具有2至20个碳原子的α-烯烃聚合得到的具有16至40个碳原子的α-烯烃寡聚物及其氢化衍生物之一；通过使用金属茂催化剂得到的α-烯烃二聚物所得到的具有16至40个碳原子的α-烯烃寡聚物及其氢化衍生物之一；等等。该润滑油组合物具有优异的低温流动性、低挥发性和良好的氧化稳定性。
• Phenolic esteramide antioxidants and their use
  申请人：UNIROYAL, INC.

  公开号：EP0009866A1

  公开（公告）日：1980-04-16

  A phenolic esteramide, useful in protecting organic materials such as synthetic and natural rubbers, petroleum products, and plastics from oxidative degradation, has the formula R' COOANHM wherein A is C2 to C12 alkylene, C4 to C8 cycloalkylene or -CH2-C(CH2)p, wherein p is an integer from 3 to 6, or A is C2 to C5 alkylene substituted with one or two -CH2OCO(CH2)mR3 groups, wherein R3 is 3-W-5-Y-4-hydroxyphenyl, wherein W and Y may be the same or different and are C, to C12 alkyl and m is 0, 1 or 2; R1 is -(CH2)mR3. wherein m and R3 are as defined above, and M is either hydrogen or-COR2, wherein R2 is C1 to C20 alkyl, C6 to C10 aryl or phenyl substituted with halogen, C1 to C12 alkyl, C1 to C12 alkoxy, nitro or hydroxy or R2 is -BCONHAOCOR1 wherein A and R1 are as defined above and B is a single bond, C1 to C10 alkylene, phenylene, C4 to C12 oxydialkylene or C. to C12 thiodialkylene, or R2 is the same as R1 which is defined above. Methods of preparing the esteramide, compositions containing them and methods of using them are also described.

  一种酚酯酰胺可用于保护合成橡胶、天然橡胶、石油产品和塑料等有机材料免于氧化降解，其式为 R' COOANHM 其中 A 为 C2 至 C12 亚烷基、C4 至 C8 环亚烷基或 -CH2-C(CH2)p、其中 p 是 3 至 6 的整数，或者 A 是被一个或两个 -CH2OCO(CH2)mR3 基团取代的 C2 至 C5 亚烷基，其中 R3 是 3-W-5-Y-4- 羟基苯基，其中 W 和 Y 可以相同或不同，并且是 C 至 C12 烷基，m 是 0、1 或 2；R1 是-(CH2)mR3。其中m和R3如上定义，且M为氢或-COR2，其中R2为被卤素、C1～C12烷基、C1～C12烷氧基、硝基或羟基取代的C1～C20烷基、C6～C10芳基或苯基，或R2为-BCONHAOCOR1，其中A和R1如上定义，且B为单键、C1～C10亚烷基、亚苯基、C4～C12氧基二亚烷基或C.～C12硫代二亚烷基，或R2与如上定义的R1相同。还描述了制备酯酰胺的方法、含有酯酰胺的组合物和使用方法。