1-溴-1,1-二氟-2-庚烯 | 262296-38-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 中文名称: 1-溴-1,1-二氟-2-庚烯
• 英文名称: (E)-1-bromo-1,1-difluorohept-2-ene
• 英文别名: 1-Bromo-1,1-difluoro-2-heptene
• CAS: 262296-38-8
• 化学式: C₇H₁₁BrF₂
• 分子量: 213.065
• InChiKey: LQSFBLRBYQAEKS-AATRIKPKSA-N

物化性质

• 沸点：
  78-82°C/60mm
• 密度：
  1.316±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险等级：
  IRRITANT

反应信息

• 作为产物：
  描述：

  1,3-二溴-1,1-二氟庚烷 在 三乙胺 作用下， 反应 28.0h， 生成 (Z)-1-bromo-1,1-difluorohept-2-ene 、 1-溴-1,1-二氟-2-庚烯
  参考文献：
  名称：

  A convenient synthesis of bromodifluoromethyl-substituted alkenes

  摘要：

  Various functionalized bromodifluoromethyl-substituted alkenes have been prepared by addition of dibromodifluoromethane to functionalized alkenes promoted by a CrCl3/Fe bimetal redox system, followed by dehydrobromination with KF/Al2O3.

  DOI：

  10.1016/0022-1139(93)03051-m

文献信息

• Synthesis of bromodifluoromethyl-substituted alkenes. Potassium fluoride supported on alumina as a dehydrobrominating agent
  作者：Chang-Ming Hu、Jian Chen

  DOI：10.1016/0022-1139(93)02954-d

  日期：1994.1

  Potassium fluoride supported on alumina is an efficient dehydrobrominating agent. 1,3-Dibromo-1,1-difluoroalkanes - adducts of dibromodifluoromethane and alkenes - give bromodifluoromethyl-substituted alkenes 2 on dehydrobromination with this agent in good to excellent yields. Alkenes 2 were a mixture of Z- and E-isomers, with the former predominating. Functional groups such as ester, carbonyl, ethylenic and chloromethyl are not affected under such reaction conditions.
• A convenient synthesis of bromodifluoromethyl-substituted alkenes
  作者：Chang-Ming Hu、Jian Chen

  DOI：10.1016/0022-1139(93)03051-m

  日期：1994.10

  Various functionalized bromodifluoromethyl-substituted alkenes have been prepared by addition of dibromodifluoromethane to functionalized alkenes promoted by a CrCl3/Fe bimetal redox system, followed by dehydrobromination with KF/Al2O3.