1-羟基-4-(丙烷-2-基氨基)蒽-9,10-二酮 | 28842-48-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 1-羟基-4-(丙烷-2-基氨基)蒽-9,10-二酮
• 英文名称: 1-isopropylamino-4-hydroxy-anthraquinone
• 英文别名: 1-Hydroxy-4-[(propan-2-yl)amino]anthracene-9,10-dione；1-hydroxy-4-(propan-2-ylamino)anthracene-9,10-dione
• CAS: 28842-48-0
• 化学式: C₁₇H₁₅NO₃
• 分子量: 281.311
• InChiKey: QQOJBTKAGBIFRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  异丙胺 、 1-羟基-4-(丙烷-2-基氨基)蒽-9,10-二酮 以 乙腈 为溶剂， 生成 透明蓝AP
  参考文献：
  名称：

  Concerning the question of covalent bonding in hypericin-chromoproteins: Schiff base formation?

  摘要：

  Depending on the reaction conditions, peri-hydroxy substituted anthraquinones like 1,8-dihydroxyanthraquinone and 1,4-dihydroxyanthraquinone could be derivatized with ammonia, propylamine, isopropylamine, and a lysine derivative to yield a variety of imino and amino substitution and addition products. However, hypericin resisted such derivatization under a variety of reaction conditions. Therefore, the hypothesis that hypericin is bound to its apoprotein in photopigments via a Schiff base to the epsilon-amino group of a lysine residue or a terminal amino group seems to be rather unlikely.

  DOI：

  10.1007/bf00811317
• 作为产物：
  描述：

  1,4-二羟基蒽醌 、 异丙胺 以 乙腈 为溶剂， 以15%的产率得到1-羟基-4-(丙烷-2-基氨基)蒽-9,10-二酮
  参考文献：
  名称：

  Concerning the question of covalent bonding in hypericin-chromoproteins: Schiff base formation?

  摘要：

  Depending on the reaction conditions, peri-hydroxy substituted anthraquinones like 1,8-dihydroxyanthraquinone and 1,4-dihydroxyanthraquinone could be derivatized with ammonia, propylamine, isopropylamine, and a lysine derivative to yield a variety of imino and amino substitution and addition products. However, hypericin resisted such derivatization under a variety of reaction conditions. Therefore, the hypothesis that hypericin is bound to its apoprotein in photopigments via a Schiff base to the epsilon-amino group of a lysine residue or a terminal amino group seems to be rather unlikely.

  DOI：

  10.1007/bf00811317

文献信息

• COLORED CHARGED SILSESQUIOXANES
  申请人：BASF SE

  公开号：US20160075725A1

  公开（公告）日：2016-03-17

  The present invention provides salts of a cation and an anion, wherein the cation comprises (i) a silsesquioxane moiety of formula (ii) a chromophoric moiety D, which may which may be substituted with one or more substituents selected from the group consisting of C 1-10 -alkyl, phenyl, halogen, OC 1-6 -alkyl, OH, NH 2 and NO 2 , and (iii) a moiety of formula wherein L 4 is C 1-20 -alkylene, phenylene-C 1-20 -alkylene or C 1-20 -alkylene-phenylene-C 1-20 alkylene, R 11 , R 12 , R 13 and R 14 are independently from each other hydrogen or C 1-4 -alkyl, R 15 , R 16 , R 17 and R 18 are independently from each other C 1-4 -alkyl, R 19 is C 1-20 -alkyl, which may be substituted with phenyl, O—C 1-6 -alkyl or NO 2 , and d is an integer from 1 to 25, and electrophoretic devices comprising the salts.

  本发明提供了一种阳离子和阴离子的盐，其中该阳离子包括(i) 公式的硅倍半氧烷基团(ii) 一种色团基团D，该色团基团D可以被选自C1-10-烷基、苯基、卤素、OC1-6-烷基、羟基、NH2和NO2的一种或多种取代基所取代，以及(iii) 一种公式的基团L4为C1-20-烷基、苯基-C1-20-烷基或C1-20-烷基-苯基-C1-20-烷基，R11、R12、R13和R14彼此独立地为氢或C1-4-烷基，R15、R16、R17和R18彼此独立地为C1-4-烷基，R19为C1-20-烷基，该烷基可以被苯基、O-C1-6-烷基或NO2取代，d为1到25的整数，以及包括该盐的电泳设备。
• Colored Charged Silsesquioxanes
  申请人：Ohrlein Reinhold

  公开号：US20140296518A1

  公开（公告）日：2014-10-02

  The present invention provides compounds of formula wherein is wherein is and electrophoretic devices comprising the compounds of formula (1A) or (1B).
• US9228063B2
  申请人：——

  公开号：US9228063B2

  公开（公告）日：2016-01-05
• US9630982B2
  申请人：——

  公开号：US9630982B2

  公开（公告）日：2017-04-25
• Concerning the question of covalent bonding in hypericin-chromoproteins: Schiff base formation?
  作者：H. Falk、N. M�ller、M. Oberreiter

  DOI：10.1007/bf00811317

  日期：1994.3

  Depending on the reaction conditions, peri-hydroxy substituted anthraquinones like 1,8-dihydroxyanthraquinone and 1,4-dihydroxyanthraquinone could be derivatized with ammonia, propylamine, isopropylamine, and a lysine derivative to yield a variety of imino and amino substitution and addition products. However, hypericin resisted such derivatization under a variety of reaction conditions. Therefore, the hypothesis that hypericin is bound to its apoprotein in photopigments via a Schiff base to the epsilon-amino group of a lysine residue or a terminal amino group seems to be rather unlikely.