2,2,2-三氟-1-呋喃-3-基-乙醇 | 722491-62-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 中文名称: 2,2,2-三氟-1-呋喃-3-基-乙醇
• 英文名称: 2,2,2-Trifluoro-1-furan-3-yl-ethanol
• 英文别名: 2,2,2-trifluoro-1-(furan-3-yl)ethanol
• CAS: 722491-62-5
• 化学式: C₆H₅F₃O₂
• 分子量: 166.1
• InChiKey: WFXXBPYHFCQFJZ-UHFFFAOYSA-N

物化性质

• 沸点：
  40°C 0,1mm
• 密度：
  1.387±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  33.4
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• INJECTABLE FORMULATION FOR TREATMENT AND PROTECTION OF PATIENTS HAVING AN INFLAMMATORY REACTION OR AN ISCHEMIA-REPERFUSION EVENT
  申请人：University of Zürich

  公开号：EP2459182A1

  公开（公告）日：2012-06-06
• Injectable Formulation for Treatment and Protection of Patients Having an Inflammatory Reaction or an Ischemia-Reperfusion Event
  申请人：ETH ZURICH

  公开号：US20140100278A1

  公开（公告）日：2014-04-10

  The present invention relates to compounds according to formula (I) for medical use. The compounds are particularly suitable for the treatment and/or prevention of a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue. Furthermore, the invention relates to the use of said compounds for preparing a medicament and to pharmaceutical preparations comprising such compounds. The invention also relates to methods of treating or protecting patients having or being prone to develop a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue, the methods comprising administration of a therapeutically effective amount of such compounds.
• US9296678B2
  申请人：——

  公开号：US9296678B2

  公开（公告）日：2016-03-29
• [EN] INJECTABLE FORMULATION FOR TREATMENT AND PROTECTION OF PATIENTS HAVING AN INFLAMMATORY REACTION OR AN ISCHEMIA-REPERFUSION EVENT<br/>[FR] FORMULATION INJECTABLE DE TRAITEMENT ET DE PROTECTION DE PATIENTS SOUFFRANT DE RÉACTION INFLAMMATOIRE OU D’UN ÉVÉNEMENT D'ISCHÉMIE-REPERFUSION
  申请人：UNIV ZUERICH

  公开号：WO2011012283A1

  公开（公告）日：2011-02-03

  The present invention relates to compounds according to formula (I) for medical use. The compounds are particularly suitable for the treatment and/or prevention of a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue. Furthermore, the invention relates to the use of said compounds for preparing a medicament and to pharmaceutical preparations comprising such compounds. The invention also relates to methods of treating or protecting patients having or being prone to develop a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue, the methods comprising administration of a therapeutically effective amount of such compounds.