申请人:The Administrators of the Tulane Educational Fund
公开号:US20200105513A1
公开(公告)日:2020-04-02
Calibrants and methods of making the same include using mixtures of multifunctional core compounds or multifunctional dendrimers that are functionalized to yield a set of discrete compounds which cover a range of collisional cross sections (CCSs) for calibrating ion mobility and variation in molecular weight to calibrate the mass to charge (m/z) measurements of mass spectrometry, as well as for calibrating tandem instruments that measure both dimensions. Methods of using the calibrants are also disclosed, such as in mass spectrometry.
校准物和制备方法包括使用多功能核心化合物或多功能树状分子的混合物,这些化合物被官能化以产生一系列离子碰撞截面(CCSs)的离散化合物,以校准离子迁移和分子量变化,以校准质荷比(m/z)质谱测量的质量,并用于校准同时测量两个维度的串联仪器。还公开了使用校准物的方法,例如在质谱分析中。