2,3,4-三氯苯磺酸 | 52106-01-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,3,4-三氯苯磺酸
• 英文名称: 2,3,4-trichloro-benzenesulfonic acid
• 英文别名: 2,3,4-Trichlor-benzolsulfonsaeure；trichlorobenzenesulfonic acid；2.3.4-Trichlor-benzolsulfonsaeure；2,3,4-trichlorobenzenesulfonic Acid
• CAS: 52106-01-1
• 化学式: C₆H₃Cl₃O₃S
• 分子量: 261.513
• InChiKey: BWRJIDMRILXEDW-UHFFFAOYSA-N

物化性质

• 密度：
  1.766±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  62.8
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2904909090

制备方法与用途

用途：利尿酸的中间体。

生产方法：通过使用1,2,3-三氯苯与发烟硫酸磺化反应制得，进一步成盐后得到磺酸钠。

反应信息

• 作为产物：
  描述：

  三氯苯 在 硫酸 、 三氧化硫 作用下， 生成 2,3,4-三氯苯磺酸 、 2,3,4-trichloro-benzenesulfonic acid-anhydride
  参考文献：
  名称：

  Lukaschewitsch, Doklady Akademii Nauk SSSR, 1954, vol. 99, p. 995,997

  摘要：

  DOI：

文献信息

• Polymer for photoresist, method of production thereof and photoresist composition containing polymer
  申请人：——

  公开号：US20020015906A1

  公开（公告）日：2002-02-07

  A polymer for a photoresist composition is given by the formula (I): 1 wherein R 1 is a hydrogen atom or a methyl group, R 2 is a C 1-12 linear or branched alkyl, haloalkyl or alkoxycarbonyl group, a C 5-12 cyclic alkyl, cyclic haloalkyl or cyclic alkoxycarbonyl group, a phenyl group or a naphthyl group, R 3 is a C 1-12 linear or branched alkyl or haloalkyl group, a C 5-12 cyclic alkyl or cyclic haloalkyl group, a phenyl group, or a naphthyl group, R 4 and R 5 are independently a hydrogen atom, a C 1-6 linear or branched alkyl, or a C 5-6 cyclic alkyl group, R′ and R″ are independently a hydrogen atom, a halogen atom, a C 1-8 alkyl or alkoxy group, a hydroxy group, a carbonate group or a phenyl group, and m, n, p and q are independently an integer provided that m and q are not zero, at least one of n and p are not zero, 0.4≦m/(m+n+p+q)≦0.9, 0≦n/(m+n+p+q)≦0.5, 0≦p/(m+n+p+q)≦0.5, and 0.01≦q/(m+n+p+q)≦0.3.

  给出了一种用于光阻组合物的聚合物，其化学式为（I）：其中R1是氢原子或甲基基团，R2是C1-12线性或支链烷基，卤代烷基或烷氧羰基基团，C5-12环烷基，环卤代烷基或环烷氧羰基基团，苯基或萘基，R3是C1-12线性或支链烷基或卤代烷基，C5-12环烷基或环卤代烷基，苯基或萘基，R4和R5分别是氢原子，C1-6线性或支链烷基或C5-6环烷基基团，R'和R"分别是氢原子，卤素原子，C1-8烷基或烷氧基团，羟基，碳酸酯基或苯基，m，n，p和q是整数，其中m和q不为零，n和p中至少有一个不为零，0.4≤m/(m+n+p+q)≤0.9，0≤n/(m+n+p+q)≤0.5，0≤p/(m+n+p+q)≤0.5，0.01≤q/(m+n+p+q)≤0.3。
• Sulfonium salt compound and resist composition and pattern forming method using the same
  申请人：NEC CORPORATION

  公开号：US20020045122A1

  公开（公告）日：2002-04-18

  The present invention relates to a photo acid generator which has high transparency to exposure light and also has excellent heat stability in a photoresist composition for lithography using far ultraviolet light, especially light of ArF excimer laser. The photo acid generator contains a sulfonium salt compound represented by the following general formula (1): 1 wherein R 1 represents an alkylene group, or an alkylene group having an oxo group, R 2 represents a straight-chain, branched-chain, monocyclic, polycyclic or bridged cyclic alkyl group having an oxo group, or a straight-chain, branched-chain, monocyclic, polycyclic or bridged cyclic alkyl group, provided that either of R 1 and R 2 has an oxo group, and Y − represents a counter ion.

  本发明涉及一种具有对紫外线透明度高并且在使用远紫外光（尤其是ArF准分子激光）的光刻用光阻组合物中具有优异的热稳定性的光酸发生剂。该光酸发生剂包含下式（1）所表示的烷基硫鎓盐化合物：其中，R1表示烷基，或者具有氧代基的烷基，R2表示具有氧代基的直链、支链、单环、多环或桥环烷基，或者直链、支链、单环、多环或桥环烷基，只要R1和R2中的任意一个具有氧代基，Y-表示反离子。
• Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
  申请人：Pulici Maurizio

  公开号：US20050020583A1

  公开（公告）日：2005-01-27

  Compounds which are amino-phthalazinone derivatives according to formula 1 and pharmaceutically acceptable salts thereof, together with pharmaceutical compositions comprising them are disclosed; these compounds or compostions are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, autoimmune diseases and neurodegenerative disorders.

  公开了按照式1的氨基-菲嗪酮衍生物和其药学上可接受的盐，以及包含它们的制药组合物；这些化合物或组合物在治疗由于和/或与改变的蛋白激酶活性有关的疾病中是有用的，如癌症，细胞增殖性疾病，阿尔茨海默病，病毒感染，自身免疫性疾病和神经退行性疾病。
• Tetracyclic pyrazole derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
  申请人：Vanotti Ermes

  公开号：US20060264493A1

  公开（公告）日：2006-11-23

  The present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a tetracyclic pyrazole. The invention also provides specific tetracyclic pyrazole derivatives, useful intermediates, a library comprising at least two of them, a process for their preparation and the pharmaceutical compositions containing them, which are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.

  本发明提供了一种治疗由改变的蛋白激酶活性引起和/或相关的疾病的方法，包括向需要治疗的哺乳动物中给予有效量的四环吡唑。本发明还提供了特定的四环吡唑衍生物、有用的中间体、包含至少两个四环吡唑衍生物的库、它们的制备方法以及含有它们的药物组合物，这些组合物对于治疗由改变的蛋白激酶活性引起和/或相关的疾病，如癌症、细胞增殖性疾病、病毒感染、自身免疫性疾病和神经退行性疾病非常有用。
• METHOD FOR PRODUCING ALPHA-ALLYLATED CYCLOALKANONE
  申请人：Kao Corporation

  公开号：US20220153671A1

  公开（公告）日：2022-05-19

  Provided is a method with which an α-allylated cycloalkanone is obtained from a cyclic compound cycloalkanone used as a starting material. The method is a method for producing an α-allylated cycloalkanone represented by General Formula (III), and the method includes: a step 1: reacting a compound represented by General Formula (I) and alcohol having 1 or more and 4 or less of carbon atoms in the presence of a first acid catalyst and optionally a dehydrating agent; and a step 2: reacting a crude product obtained in the step 1 and a compound represented by General Formula (II) in the presence of a second acid catalyst to produce an α-allylated cycloalkanone represented by General Formula (III). The step 1 and the step 2 are consecutively performed. In the formulae above, the group -A 1 - (it should be noted that the front bond refers to a bond that binds to the carbon atom C 1 and the back bond refers to a bond that binds to the carbon atom C 2 ) is an alkylene group having 4 or more and 20 or less of carbon atoms that optionally contains a hetero atom and optionally has a substituent, and R 4 is a hydrogen atom or an alkyl group having 1 or more and 4 or less of carbon atoms.

  提供的是一种方法，通过将环状化合物环状酮用作起始材料，得到α-烯丙基化环状酮。该方法是生产由通式（III）表示的α-烯丙基化环状酮的方法，该方法包括：步骤1：在第一酸性催化剂和可选的脱水剂的存在下，使通式（I）表示的化合物和具有1个或多个碳原子和4个或更少碳原子的醇反应; 步骤2：在第二酸性催化剂的存在下，使步骤1得到的粗产品和通式（II）表示的化合物反应，以生产由通式（III）表示的α-烯丙基化环状酮。步骤1和步骤2是连续执行的。在上述公式中，-A1-基团（应注意前面的键指绑定到碳原子C1的键，后面的键指绑定到碳原子C2的键）是具有4个或多个碳原子和20个或少的碳原子的烷基基团，可选地含有杂原子和可选地具有取代基，而R4是氢原子或具有1个或多个碳原子和4个或更少碳原子的烷基基团。