2,3-二溴-2-甲基-己烷 | 100859-79-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机溴化物
• 中文名称: 2,3-二溴-2-甲基-己烷
• 英文名称: 2,3-dibromo-2-methyl-hexane
• 英文别名: 2,3-Dibrom-2-methyl-hexan；2.3-Dibrom-2-methyl-hexan；2,3-dibromo-2-methylhexane
• CAS: 100859-79-8
• 化学式: C₇H₁₄Br₂
• 分子量: 257.996
• InChiKey: OSIUNUSGFYULIA-UHFFFAOYSA-N

物化性质

• 沸点：
  75-78 °C(Press: 6 Torr)
• 密度：
  1.5116 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2,3-二溴-2-甲基-己烷 在 水 作用下， 生成 2-甲基-3-己酮
  参考文献：
  名称：

  Evers et al., Journal of the American Chemical Society, 1933, vol. 55, p. 1138

  摘要：

  DOI：
• 作为产物：
  描述：

  2-甲基-2-己烯 在 四氯化碳 、 N-溴代丁二酰亚胺(NBS) 作用下， 生成 2,3-二溴-2-甲基-己烷
  参考文献：
  名称：

  Comparison of N-Bromoacetamide and N-Bromosuccinimide as Brominating Agents¹

  摘要：

  DOI：

  10.1021/jo01352a014

文献信息

• FimZ Binds the<i>Salmonella typhimurium fimA</i>Promoter Region and May Regulate Its Own Expression with FimY
  作者：Kuang-sheng Yeh、Juliette K. Tinker、Steven Clegg

  DOI：10.1111/j.1348-0421.2002.tb02670.x

  日期：2002.1

  AbstractThe FimZ protein, an activator of FimA production in Salmonella typhimurium, acts in conjunction with FimY to facilitate the expression of type 1 fimbriae. The predicted amino acid sequence of FimZ suggests that this protein may be a DNA‐binding protein related to BvgA, a sensory regulator of virulence gene expression in Bordetella pertussis. Purification of FimZ following overexpression of the protein by a strong inducible promoter and gel mobility shift assays confirm that FimZ is a 25‐kDa polypeptide that binds to the promoter region of fimA. The region of DNA protected from DNase I digestion by FimZ binding is located between 47 and 98 nucleotides upstream from the fimA transcription initiation site. This region possesses a pair of 7‐base pair tandem repeats, of which at least one is necessary for FimZ binding. One copy of the 7‐base pair sequence is also located in the fimZ promoter region. In addition, expression from a fimZ‐lacZ reporter construct confirms that FimZ plays a role in its own expression. Both FimZ and FimY are required for high‐level expression of FimZ, which suggests that these two fimbrial proteins are involved in regulating both FimA and FimZ.
• NOTE
  作者：Hurd、Bennett

  DOI：10.1021/ja01387a033

  日期：1929.12
• Pansewitsch-Koljada; Idel'tschik, Zhurnal Obshchei Khimii, 1954, vol. 24, p. 1617,1622, engl. Ausg. S. 1601, 1604
  作者：Pansewitsch-Koljada、Idel'tschik

  DOI：——

  日期：——
• Evers et al., Journal of the American Chemical Society, 1933, vol. 55, p. 1138
  作者：Evers et al.

  DOI：——

  日期：——
• Comparison of N-Bromoacetamide and N-Bromosuccinimide as Brominating Agents¹
  作者：ROBERT E. BUCKLES、ROBERT C. JOHNSON、WILLIAM J. PROBST

  DOI：10.1021/jo01352a014

  日期：1957.1