4-fluoro-N-[3-(hydroxymethyl)phenyl]benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-fluoro-N-[3-(hydroxymethyl)phenyl]benzamide
• 化学式: C₁₄H₁₂FNO₂
• mdl: MFCD13238519
• 分子量: 245.25
• InChiKey: QXZWQORZDRNIJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.071
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• IMIDAZOPYRIDAZINE AND IMIDAZOTHIADIAZOLE COMPOUNDS
  申请人：Universite de Montreal

  公开号：US20180237457A1

  公开（公告）日：2018-08-23

  The present invention provides imidazopyridazine compounds or imidazothiadiazole compounds of Formula I having the structure: (I) wherein X 1 , X 2 , X 3 , X 4 , X 5 , Y, W, R 1 , R 2 , R 3 , R 4 , R 5 and (II) are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.