2-(2,3,6-三氯苯基)乙酸钠 | 2439-00-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-(2,3,6-三氯苯基)乙酸钠
• 中文别名: 吡啶,2-(甲硫基)-6-(三甲基甲硅烷基)-(9CI)
• CAS: 2439-00-1
• 化学式: C8H5Cl3NaO2
• 分子量: 262.5
• InChiKey: NZXJVNMQYWHOLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.89
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Polylactic acid type microspheres containing physiologically active substance and process for preparing the same
  申请人：Biomaterials Universe, Inc.

  公开号：EP0330180A1

  公开（公告）日：1989-08-30

  Microspheres comprising polylactic acid and a water soluble physiologically active substance and having a mean particle size of from about 0.01 µm to 300 µm, which show not more than 30 % of an eluted amount of said physio­logically active substance based on the content of said physiologically active substance in the polylactic acid type microspheres after 24 hours in in vitro elution test in phosphate buffer of pH 7.4 at 37°C, and a process for preparing the same. The polylactic acid type microspheres of this invention is advantageous in that the active substance can be uniformly incorporated into the micro­spheres without loss of the activity, can gradually release the active substance for a long time of period of more than one week.

  由聚乳酸和水溶性生理活性物质组成的微球，其平均粒径约为0.01微米至300微米，在37℃、pH值为7.4的磷酸盐缓冲液中进行体外洗脱试验24小时后，根据聚乳酸型微球中所述生理活性物质的含量，所述生理活性物质的洗脱量不超过30%，以及制备该微球的工艺。本发明的聚乳酸型微球的优点是活性物质可以均匀地掺入微球中而不损失活性，可以在一周以上的长时间内逐渐释放活性物质。
• TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：EP3238540A1

  公开（公告）日：2017-11-01

  The present invention relates to a timed-release-type granular agrochemical composition formed by coating primary granules that comprise a mixed composition containing an agrochemical active ingredient, a swelling substance, a surfactant, and, depending on the circumstances, the other formulants; the primary granules being coated with a mixed composition containing a binder, a hydrophobic substance, a carrier, and, depending on the circumstances, the other formulants.

  本发明涉及一种定时释放型颗粒农用化学品组合物，该组合物通过包覆初级颗粒形成，初级颗粒包含一种农用化学品活性成分、一种膨胀物质、一种表面活性剂以及（视情况而定）其他配方剂的混合组合物；初级颗粒包覆有一种包含粘合剂、一种疏水性物质、一种载体以及（视情况而定）其他配方剂的混合组合物。
• APPLICATION OF TRANSTHYRETIN IN ENTERING EYE AND PREPARING DROP
  申请人：Yizhou (Shanghai) Biological Medicine Co, Ltd.

  公开号：EP3988122A1

  公开（公告）日：2022-04-27

  The present invention provides an application of transthyretin serving as a carrier for a protein and/or polypeptide drug to enter an eye through an eye barrier. The transthyretin is a protein consisting of amino acid as shown in SEQ ID NO: 1 or a mutation thereof or a modification thereof. Further provided are an application of transthyretin and/or a fusion protein of the transthyretin and a drug in preparation of a drop, and a drop. The drug is a protein and/or polypeptide drug. The transthyretin has good biocompatibility and safety in human bodies, can effectively convey a foreign protein and/or polypeptide into the eye, and achieves an effect of treating eye diseases.

  本发明提供了一种转甲状腺素的应用，作为蛋白质和/或多肽药物的载体，通过眼屏障进入眼睛。转甲状腺素是由 SEQ ID NO: 1 所示氨基酸或其突变或其修饰组成的蛋白质。进一步提供了转甲状腺素和/或转甲状腺素与药物的融合蛋白在滴剂制备中的应用，以及滴剂。药物为蛋白质和/或多肽药物。转甲状腺素在人体中具有良好的生物相容性和安全性，能有效地将外来蛋白质和/或多肽输送到眼内，达到治疗眼疾的效果。
• Cover layers to prevent weed growth
  申请人：Slanghek Maximiliaan Theodoor

  公开号：US20050279019A1

  公开（公告）日：2005-12-22

  The invention relates to a soil cover, a method for preventing weed growth by using a soil cover, the use of potato steam peels and the use of a cork fraction of potato steam peels for preventing weed growth. A soil cover according to the invention comprises potato steam peels or a part, derivative or analogue thereof. In a different embodiment, a soil cover according to the invention comprises a cork fraction of potato steam peels or a part, derivative or analogue thereof.

  本发明涉及一种土壤覆盖物、一种通过使用土壤覆盖物防止杂草生长的方法、马铃薯蒸汽果皮的使用以及马铃薯蒸汽果皮软木部分用于防止杂草生长的使用。根据本发明，土壤覆盖物包括马铃薯蒸汽皮或其部分、衍生物或类似物。在另一个不同的实施方案中，根据本发明的土壤覆盖物包括马铃薯蒸汽皮的软木部分或其部分、衍生物或类似物。
• COVER LAYERS TO PREVENT WEED GROWTH
  申请人：NEDERLANDSE ORGANISATIE VOORTOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO

  公开号：EP1562415A1

  公开（公告）日：2005-08-17