2-(2,4-二氯苯氧基)丙酸2-丁氧基乙醇酯 | 53404-31-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-(2,4-二氯苯氧基)丙酸2-丁氧基乙醇酯
• 中文别名: 二氯丙基-2-丁基乙基酯
• 英文名称: Dichlorprop-butotyl
• 英文别名: 2-butoxyethyl 2-(2,4-dichlorophenoxy)propanoate
• CAS: 53404-31-2
• 化学式: C₁₅H₂₀Cl₂O₄
• 分子量: 335.2
• InChiKey: NCMJQZVNCFTQPG-UHFFFAOYSA-N

物化性质

• 溶解度：
  In water, 1.049 mg/L at 25 °C (est)
• 蒸汽压力：
  4.05X10-6 mm Hg at 25 °C (est)
• 稳定性/保质期：

  Stable under recommended storage conditions.

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

ADMET

毒理性

• 毒性总结

识别和使用：丁基二氯丙已不再在美国生产或使用。人体研究：无数据可用。动物研究：无数据可用。

IDENTIFICATION AND USE: Dichlorprop-butotyl is no longer produced or used in the US. HUMAN STUDIES: There are no data available. ANIMAL STUDIES: There are no data available.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

/SRP:/ 立即急救：确保已经进行了充分的中毒物清除。如果患者停止呼吸，开始人工呼吸，最好使用需求阀复苏器、袋阀面罩装置或口袋面罩，按训练操作。根据需要执行心肺复苏。立即用缓慢流动的水冲洗受污染的眼睛。不要催吐。如果发生呕吐，让患者前倾或将其置于左侧卧位（如果可能的话，头部向下）以保持呼吸道畅通，防止吸入性肺炎。保持患者安静，维持正常体温。寻求医疗救助。 /氯苯氧基除草剂及相关化合物/

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Chlorophenoxy herbicides and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

/SRP:/ 基本治疗：建立专利气道（如有需要，使用口咽或鼻咽气道）。如有必要，进行吸痰。观察呼吸不足的迹象，如有必要，进行辅助通气。通过非重复呼吸面罩以10至15升/分钟的速度给予氧气。监测肺水肿，并在必要时进行治疗……。监测休克，并在必要时进行治疗……。预期可能出现癫痫，并在必要时进行治疗……。对于眼睛污染，立即用水冲洗眼睛。在运输过程中，用0.9%的生理盐水（NS）连续冲洗每只眼睛……。不要使用催吐剂。对于摄入，如果患者能够吞咽、有强烈的呕吐反射且不流口水，则用水冲洗口腔，并给予5毫升/千克，最多200毫升的水进行稀释。给予活性炭……。监测体温，并在必要时进行治疗。/氯苯氧基除草剂及相关化合物/

/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Monitor body temperature and treat if necessary. /Chlorophenoxy herbicides and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

/SRP:/ 高级治疗：对于无意识的病人，考虑进行口咽或鼻咽气管插管以控制气道。使用气囊面罩装置的正压通气技术可能有益。考虑使用药物治疗肺水肿……监测心率和必要时治疗心律失常……开始静脉输注0.9%生理盐水（NS）或乳酸林格氏液/SRP: "保持开放"，最小流量/。调整以维持足够的尿量。对于伴有低血容量症状的低血压，谨慎给予液体。如果病人在正常液体量下仍然低血压，考虑使用血管加压药……使用地西泮（安定）或劳拉西泮（阿蒂凡）治疗癫痫……使用丙美卡因盐酸辅助眼部冲洗……/氯苯氧基除草剂及其相关化合物/

/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of 0.9% saline (NS) or lactated Ringer's /SRP: "To keep open", minimal flow rate/. Titrate to maintain adequate urine flow. For hypotension with signs of hypovolemia, administer fluid cautiosly. Consider vasopressors if patient is hypotensive with a normal fluid volume ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Chlorophenoxy herbicides and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

1. 通过使用肥皂和水洗澡以及使用洗发水来清洁皮肤和头发。有慢性皮肤病或对这些除草剂过敏的人应避免使用它们，或者采取严格预防措施以避免接触（如使用防毒面具、手套等）。/氯苯氧基除草剂/

1. Decontaminate skin and hair by bathing with soap and water and shampooing. Individuals with chronic skin disease or known sensitivity to these herbicides should either avoid using them or take strict precautions to avoid contact (respirator, gloves, etc). /Chlorophenoxy herbicides/

来源:Hazardous Substances Data Bank (HSDB)

文献信息

• HERBICIDAL COMPOSITIONS
  申请人：Bayer Aktiengesellschaft

  公开号：US20220053762A1

  公开（公告）日：2022-02-24

  The present invention provides compositions comprising herbicidally active compounds (A) and (B), where (A) represents one or more compounds of the general formula (I) or agrochemically compatible salts thereof [component (A)], and (B) represents one or more herbicides [component (B)]. The application further relates to a method and to the use of the herbicidal composition according to the invention for controlling harmful plants or for regulating growth.

  本发明提供了包含除草活性化合物（A）和（B）的组合物，其中（A）代表通式（I）的一个或多个化合物或其农药兼容盐[组分（A）]，（B）代表一个或多个除草剂[组分（B）]。该申请进一步涉及一种方法和利用本发明的除草组合物来控制有害植物或调节生长。
• Stabilized oil-in-water emulsions
  申请人：RHONE-POULENC AGROCHIMIE

  公开号：EP0485207B1

  公开（公告）日：1997-05-28
• HERBIZIDE ZUSAMMENSETZUNGEN
  申请人：Bayer Aktiengesellschaft

  公开号：EP3890488A1

  公开（公告）日：2021-10-13
• Methods and compositions for increasing the efficacy of biologically-active ingredients
  申请人：Windsor Brian J.

  公开号：US20060276339A1

  公开（公告）日：2006-12-07

  The invention provides methods and compositions for modulating the sensitivity of cells to cytotoxic compounds and other active agents. In accordance with the invention, compositions are provided comprising combinations of ectophosphatase inhibitors and active agents. Active agents include antibiotics, fungicides, herbicides, insecticides, chemotherapeutic agents, and plant growth regulators. By increasing the efficacy of active agents, the invention allows use of compositions with lowered concentrations of active ingredients.
• [DE] HERBIZIDE ZUSAMMENSETZUNGEN<br/>[EN] HERBICIDAL COMPOSITIONS<br/>[FR] COMPOSITIONS HERBICIDES
  申请人：BAYER AG

  公开号：WO2020114932A1

  公开（公告）日：2020-06-11

  Gegenstand der vorliegenden Erfindung sind Zusammensetzungen enthaltend herbizid wirksame Verbindungen (A) und (B), wobei (A) für eine oder mehrere Verbindungen der allgemeinen Formel (I) oder deren agrochemisch verträglichen Salze [Komponente (A)] steht, und (B) für ein oder mehreren Herbizide [Komponente (B)] steht. Die Anmeldung betrifft ferner ein Verfahren sowie die Verwendung der erfindungsgemäßen herbiziden Zusammensetzung zur Bekämpfung von Schadpflanzen oder zur Wachstumsregulierung.