2-(2-乙氧基-2,2-二苯基乙酰基)氧乙基-二甲基氯化铵 | 2424-75-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-(2-乙氧基-2,2-二苯基乙酰基)氧乙基-二甲基氯化铵
• 英文名称: β-dimethylaminoethyl α,α-diphenyl-α-ethoxyacetate hydrochloride
• 英文别名: Cotocin；Estotsin；ethoxy-diphenyl-acetic acid-(2-dimethylamino-ethyl ester); hydrochloride；Aethoxy-diphenyl-essigsaeure-(2-dimethylamino-aethylester); Hydrochlorid；Dimenoxadol hydrochloride；2-(dimethylamino)ethyl 2-ethoxy-2,2-diphenylacetate;hydrochloride
• CAS: 2424-75-1
• 化学式: C₂₀H₂₅NO₃*ClH
• 分子量: 363.884
• InChiKey: ZFUFAMMRSGTUQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.34
• 重原子数：
  25
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  40
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] NOVEL MEDICINAL COMPOUNDS<br/>[FR] NOUVEAUX COMPOSÉS MÉDICINAUX
  申请人：URATIM GYARTO KORLATOLT FELELOSSEGU TARSASAG

  公开号：WO2011089457A1

  公开（公告）日：2011-07-28

  The present invention concerns novel compounds possessing the general formula (I), pharmaceutical preparations containing such active ingredients, as well as the process for manufacture thereof, where R, X, A and Q are defined in the claims. The novel compounds are efficient in the prevention and/or treatment of diseases caused by the bacterium Mycobacterium tuberculosis or any other Mycobacteria.

  本发明涉及具有一般式（I）的新化合物，含有这种活性成分的制药制剂，以及其制造过程，其中R、X、A和Q在权利要求中定义。这些新化合物对由结核分枝杆菌或任何其他分枝杆菌引起的疾病的预防和/或治疗非常有效。
• Liquid crystal composition and liquid crystal element
  申请人：Takaku Koji

  公开号：US20050072962A1

  公开（公告）日：2005-04-07

  The present invention relates to a liquid crystal composition comprising a compound represented by the following formula (1) and a liquid crystal and a liquid crystal element containing the liquid crystal composition: wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 each independently represent a hydrogen atom or a substituent; and X represents an oxygen atom or a sulfur atom.

  本发明涉及一种液晶组合物，包括以下式(1)所表示的化合物、液晶和含有该液晶组合物的液晶元件：其中，R1、R2、R3、R4、R5、R6和R7各自独立地表示氢原子或取代基；X表示氧原子或硫原子。
• Carboxylic acids
  申请人：——

  公开号：US20040116708A1

  公开（公告）日：2004-06-17

  The present invention provides a novel carboxylic acid derivative, a salt thereof or a hydrate of them which is useful as an insulin sensitizer, and a medicament comprising the derivative as the effective ingredient. More specifically, it provides a carboxylic acid compound represented by the formula (I), a salt thereof or a hydrate of them. 1 In the formula, Ar represents a 6- to 14-membered aromatic ring group which may have at least one substituent; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a C 1-6 alkyl group or a C 1-6 alkoxy group; X represents an oxygen atom or a methylene group; Y represents a group represented by the formula (II) or (III): 2 (wherein Z represents a group represented by the formula (IV): 3 (wherein R 9 , R 10 , R 11 and R 12 are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a C 1-6 alkyl group or a C 1-6 alkoxy group)); m is 0 or 1; and n is 0 or 1.

  本发明提供了一种新的羧酸衍生物，其盐或水合物可用作胰岛素增敏剂，并提供了一种以该衍生物为有效成分的药物。更具体地，本发明提供了一种由式(I)表示的羧酸化合物，其盐或水合物。在式中，Ar表示一个有6至14个成员的芳香环基团，该基团可以具有至少一个取代基；R1，R2，R3，R4，R5，R6，R7和R8相同或不同，每个表示氢原子，卤素原子，羟基，C1-6烷基或C1-6烷氧基；X表示氧原子或亚甲基；Y表示由式(II)或(III)表示的基团：其中Z表示由式(IV)表示的基团：其中R9，R10，R11和R12相同或不同，每个表示氢原子，卤素原子，羟基，C1-6烷基或C1-6烷氧基）；m为0或1；n为0或1。
• Organic electroluminescent device
  申请人：Ise Toshihiro

  公开号：US20060073360A1

  公开（公告）日：2006-04-06

  Disclosed is an organic electroluminescent device including at least one organic layer containing a luminescent layer between a pair of electrodes, wherein the organic layer contains at least one metal complex having a ligand with five or more coordination atoms.

  公开了一种有机电致发光装置，包括至少一个有机层，在一对电极之间含有一个发光层，其中该有机层含有至少一个具有五个或更多配位原子的配体的金属配合物。
• FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY
  申请人：KAWABE Satomi

  公开号：US20070227652A1

  公开（公告）日：2007-10-04

  A film for a display comprising a cellulose ester and a compound represented by Formula (I) or (Ia).

  一种用于显示器的膜，包括纤维素酯和由公式(I)或(Ia)所代表的化合物。