benzylmethyl(tetrahydropyran-4-yl)amine | 343324-62-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzylmethyl(tetrahydropyran-4-yl)amine
• 英文别名: N-benzyl-N-methyloxan-4-amine
• CAS: 343324-62-9
• 化学式: C₁₃H₁₉NO
• 分子量: 205.3
• InChiKey: PSDIWCDXNHIJPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Processes for producing tetrahydropyranyl-4-sulfonates and 4-aminotetrahydropyran compound
  申请人：——

  公开号：US20030004359A1

  公开（公告）日：2003-01-02

  The present invention is to provide a process for producing a tetrahydropyranyl-4-sulfonate which comprises allowing 3-buten-1-ol which is easily available to react with a formaldehyde compound and an organic sulfonic acid, and a process for producing a 4-aminotetrahydropyrane derivative, which is industrially useful, under mild conditions and by a simple and easy method to produce the 4-aminotetrahydropyrane derivative in high yield.

  本发明提供了一种制备四氢吡喃基-4-磺酸酯的方法，包括使易得到的3-丁烯-1-醇与甲醛化合物和有机磺酸反应；以及一种在温和条件下、通过简单易行的方法高产得到工业上有用的4-氨基四氢吡喃衍生物的方法。
• Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
  申请人：Bradley Edward Stuart

  公开号：US20050261272A1

  公开（公告）日：2005-11-24

  Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.

  化学式（I）所代表的化合物或其药学上可接受的盐，是糖原磷酸化酶的抑制剂，可用于预防或治疗糖尿病、高血糖、高胆固醇血症、高胰岛素血症、高血脂症、高血压、动脉粥样硬化或组织缺血，例如心肌缺血，并作为心脏保护剂。
• PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSPHORYLASE
  申请人：Bradley Edward Stuart

  公开号：US20070244090A9

  公开（公告）日：2007-10-18

  Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.

  式(I)所代表的化合物或其药学上可接受的盐，是糖原磷酸化酶的抑制剂，可用于预防或治疗糖尿病、高血糖、高胆固醇血症、高胰岛素血症、高脂血症、高血压、动脉粥样硬化或组织缺血，例如心肌缺血，并可作为心脏保护剂。
• PROCESSES FOR PRODUCING TETRAHYDROPYRANYL-4-SULFONATE AND 4-AMINOTETRAHYDROPYRAN COMPOUND
  申请人：Ube Industries, Ltd.

  公开号：EP1247807A1

  公开（公告）日：2002-10-09

  The present invention is to provide a process for producing a tetrahydropyranyl-4-sulfonate which comprises allowing 3-buten-1-ol which is easily available to react with a formaldehyde compound and an organic sulfonic acid, and a process for producing a 4-aminotetrahydropyrane derivative, which is industrially useful, under mild conditions and by a simple and easy method to produce the 4-aminotetrahydropyrane derivative in high yield.

  本发明旨在提供一种生产四氢吡喃-4-磺酸盐的工艺，该工艺包括允许容易获得的 3-丁烯-1-醇与甲醛化合物和有机磺酸反应，以及一种生产 4-氨基四氢吡喃衍生物的工艺，该衍生物在工业上有用，条件温和，方法简单易行，可以高产率生产 4-氨基四氢吡喃衍生物。
• PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE
  申请人：Prosidion Limited

  公开号：EP1636224A2

  公开（公告）日：2006-03-22