3-(Pentafluoro-lambda6-sulfanyl)-5-(trifluoromethyl)aniline

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(Pentafluoro-lambda6-sulfanyl)-5-(trifluoromethyl)aniline
• 英文别名: 3-(pentafluoro-λ6-sulfanyl)-5-(trifluoromethyl)aniline
• 化学式: C₇H₅F₈NS
• 分子量: 287.18
• InChiKey: XQCNVTZPWIBPGG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  27
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• Polyfluorinated aromatic or heterocyclic derivatives with sulphurpentalfuoride group(s)
  申请人：——

  公开号：US20030096999A1

  公开（公告）日：2003-05-22

  The invention provides polyflurinated aromatic or heterocyclic compounds comprising at least three ring sustitutents, at least one of which comprises a sulphurpentafluoride group and at least one of which comprises a labile group; methods for their preparation are also disclosed. Preferably, the compounds comprise either two sulphurpentafluoride groups or one sulphurpentafluoride group and one other polyflurinated group, such as a trifluoromethyl group. Said labile group preferably comprises an amino, bromo or nitro group. Said compounds are useful in the preparation of medicaments.

  本发明提供了由至少三个环助剂组成的多呋喃芳香族或杂环化合物，其中至少一个环助剂包括一个五氟化硫基团，至少一个环助剂包括一个易变基团；本发明还公开了其制备方法。这些化合物最好包含两个五氟化硫基团或一个五氟化硫基团和一个其它多呋喃基团，如三氟甲基。所述易变基团最好包括氨基、溴基或硝基。所述化合物可用于制备药物。
• POLYFLUORINATED AROMATIC OR HETEROCYCLIC DERIVATIVES WITH SULPHURPENTAFLUORIDE GROUP(S)
  申请人：F2 Chemicals Limited

  公开号：EP1341756A1

  公开（公告）日：2003-09-10
• US6806388B2
  申请人：——

  公开号：US6806388B2

  公开（公告）日：2004-10-19
• [EN] POLYFLUORINATED AROMATIC OR HETEROCYCLIC DERIVATIVES WITH SULPHURPENTAFLUORIDE GROUP(S)<br/>[FR] DERIVES AROMATIQUES OU HETEROCYCLIQUES POLYFLUORES COMPRENANT UN OU PLUSIEURS GROUPES DE PENTAFLUORURE DE SOUFRE
  申请人：F2 CHEMICALS LTD

  公开号：WO2002042263A1

  公开（公告）日：2002-05-30

  The invention provides polyflurinated aromatic or heterocyclic compounds comprising at least three ring substitutents, at least one of which comprises a sulphurpentafluoride group and at least one of which comprises a labile group; methods for their preparation are also disclosed. Preferably, the compounds comprise either two sulphurpentafluoride groups or one sulphurpentafluoride group and one other polyflurinated group, such as a trifluoromethyl group. Said labile group preferably comprises an amino, bromo or nitro group. Said compounds are useful in the preparation of medicaments.