N,N'-2,6-pyridinediylbis(2-bromopropanamide) | 473917-59-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-2,6-pyridinediylbis(2-bromopropanamide)
• 英文别名: N,N'-(Pyridine-2,6-diyl)bis(2-bromopropanamide)；2-bromo-N-[6-(2-bromopropanoylamino)pyridin-2-yl]propanamide
• CAS: 473917-59-8
• 化学式: C₁₁H₁₃Br₂N₃O₂
• 分子量: 379.051
• InChiKey: ZSBVRNDSPKYQNI-UHFFFAOYSA-N

物化性质

• 沸点：
  566.4±50.0 °C(Predicted)
• 密度：
  1.814±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  71.1
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  苯二硫代甲酸 、 N,N'-2,6-pyridinediylbis(2-bromopropanamide) 以 四氢呋喃 为溶剂， 反应 15.0h， 以45%的产率得到(pyridine-2,6-diylbis(azanediyl))bis(1-oxopropane-1,2-diyl) dibenzodithioate
  参考文献：
  名称：

  Heterocomplementary H-Bonding RAFT Agents as Tools for the Preparation of Supramolecular Miktoarm Star Copolymers

  摘要：

  Supramolecular miktoarm stars (AB(2) type) composed of poly (methyl methacrylate)-polystyrene(2) (PM MA-PS. poly(isoprene)-polystyrene2 (PI-PS2), and poly(vinyl acetate)-polystyrene, (PVAc-PS2) were successfully synthesized by assembling reversible addition fragmentation chain transfer (RA FT)-polymerized chains bearing hydrogen-bonding heterocomplementary associating units To this end, thymine and diaminopyridine-Functionalized chain transfer agents were designed to efficiently mediate the polymerization of vinyl acetate, methyl methacrylate. isoprene, and styrene The selective associations of the resulting hydrogen-bonding macromolecular building blocks PVAc/PS. PI/PS, and PMMA/PS were demonstrated by H-1 NMR in CDCl3 solutions Miktoarm stars formation in the bulk was also confirmed by transmission electronic microscopy

  DOI：

  10.1021/ma101044y
• 作为产物：
  描述：

  2,6-二氨基吡啶 、 2-溴丙酰溴 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以83%的产率得到N,N'-2,6-pyridinediylbis(2-bromopropanamide)
  参考文献：
  名称：

  Synthesis and Recognition Properties of Polymers Containing Embedded Binding Sites

  摘要：

  We report the synthesis and guest affinities of polymers featuring a single recognition site in the middle of the polymer chain. These polymers were synthesized from difunctional initiators based on the 2,6-diacyldiaminopyridine moiety. Binding efficiencies were experimentally determined using a complementary fluorescent guest, N(10)-isopropyl flavin. The effect of polymer length on recognition was explored by the synthesis of 5 PMMA samples ranging from 4K to 25K. Over this range binding constants increased almost 2-fold, from 282 to 522 M-1. Variable temperature fluorescence of bound samples shows a 15% difference in release between polymer samples and model compounds.

  DOI：

  10.1021/ma0346355