3,3-Bis[(4-methylphenyl)sulfanyl]spiro[3.5]nonane | 1160784-81-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3,3-Bis[(4-methylphenyl)sulfanyl]spiro[3.5]nonane
• CAS: 1160784-81-5
• 化学式: C₂₃H₂₈S₂
• 分子量: 368.607
• InChiKey: JXCIBXVHXFKXQN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  对甲苯二硫醚 、 环亚丙基环己烷 在 四氯化钛 作用下， 以 二氯甲烷 为溶剂， 以54%的产率得到3,3-Bis[(4-methylphenyl)sulfanyl]spiro[3.5]nonane
  参考文献：
  名称：

  Lewis Acid Catalyzed Reaction of Methylenecyclopropanes with 1,2-Diphenyldiselane or 1,2-Di-p-tolyldisulfane

  摘要：

  Catalyzed by Lewis acid, 1,2-diphenyldiselane or 1,2-di-p-tolyldisulfane could add to methylenecyclopropanes smoothly. Compared with the reported free radical additions, the results were quite different. A four-membered carbon ring was constructed to give cyclobutane-1,1-diylbis(phenylselane) derivatives or cyclobutane-1,1-diylbis(p-tolylsulfane) derivatives as products, which are useful intermediates in organic synthesis.

  DOI：

  10.1021/jo9006514

文献信息

• Lewis Acid Catalyzed Reaction of Methylenecyclopropanes with 1,2-Diphenyldiselane or 1,2-Di-<i>p</i>-tolyldisulfane
  作者：Lei Yu、Jundong Meng、Ling Xia、Rong Guo

  DOI：10.1021/jo9006514

  日期：2009.7.17

  Catalyzed by Lewis acid, 1,2-diphenyldiselane or 1,2-di-p-tolyldisulfane could add to methylenecyclopropanes smoothly. Compared with the reported free radical additions, the results were quite different. A four-membered carbon ring was constructed to give cyclobutane-1,1-diylbis(phenylselane) derivatives or cyclobutane-1,1-diylbis(p-tolylsulfane) derivatives as products, which are useful intermediates in organic synthesis.