N-[(4-bromophenoxy)-(diethylamino)phosphanyl]-N-ethylethanamine | 129274-51-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(4-bromophenoxy)-(diethylamino)phosphanyl]-N-ethylethanamine
• CAS: 129274-51-7
• 化学式: C₁₄H₂₄BrN₂OP
• 分子量: 347.235
• InChiKey: YKPSWNOQWMCJJZ-UHFFFAOYSA-N

物化性质

• 沸点：
  171 °C(Press: 1 Torr)
• 密度：
  1.106 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-[(4-bromophenoxy)-(diethylamino)phosphanyl]-N-ethylethanamine 以 1,4-二氧六环 为溶剂， 反应 468.0h， 生成 N-[diethylamino(naphthalen-2-yloxy)phosphanyl]-N-ethylethanamine
  参考文献：
  名称：

  Dismutation of Diamidoarylphosphites

  摘要：

  Some examples of spontaneous dismutation of diamidoarylphosphites in different solvents were studied, and features of the process were revealed.

  DOI：

  10.1080/714040960
• 作为产物：
  描述：

  4-溴苯酚 、 六乙基亚磷酸胺 以 1,4-二氧六环 为溶剂， 反应 42.0h， 生成 N-[(4-bromophenoxy)-(diethylamino)phosphanyl]-N-ethylethanamine
  参考文献：
  名称：

  Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use

  摘要：

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.

  DOI：

  10.1134/s1070363206020046

文献信息

• O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  作者：Ramon Eritja、Valeriy Smirnov、Marvin H. Caruthers

  DOI：10.1016/s0040-4020(01)81356-9

  日期：1990.1
• ERITJA, RAMON;SMIRNOV, VALERIY;CARUTHERS, MARVIN H., TETRAHEDRON, 46,(1990) N, C. 721-730
  作者：ERITJA, RAMON、SMIRNOV, VALERIY、CARUTHERS, MARVIN H.

  DOI：——

  日期：——
• Dismutation of Diamidoarylphosphites
  作者：Edward E. Nifantyev、Elena N. Rasadkina、Pavel V. Slitikov、Larisa K. Vasyanina

  DOI：10.1080/714040960

  日期：2003.11.1

  Some examples of spontaneous dismutation of diamidoarylphosphites in different solvents were studied, and features of the process were revealed.
• Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use
  作者：E. N. Rasadkina、P. V. Slitikov、E. E. Nifant’ev

  DOI：10.1134/s1070363206020046

  日期：2006.2

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.