溴苯那敏 | 32656-44-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 溴苯那敏
• 中文别名: 右溴苯那敏
• 英文名称: (R)-brompheniramine
• 英文别名: (-)-Brompheniramine；(gammaR)-gamma-(4-Bromophenyl)-N,N-dimethyl-2-pyridinepropanamine；(3R)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
• CAS: 32656-44-3
• 化学式: C₁₆H₁₉BrN₂
• 分子量: 319.244
• InChiKey: ZDIGNSYAACHWNL-OAHLLOKOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  16.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 1,3-Bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders
  申请人：——

  公开号：US20030232877A1

  公开（公告）日：2003-12-18

  The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula 1 or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the application.

  这项发明涉及通式1的化合物、药物组合物和使用该化合物的方法，其中取代基在申请中定义。
• [EN] NOVEL SALT FORMS OF POORLY SOLUBLE PROBUCOL ESTERS AND ETHERS<br/>[FR] NOUVELLES FORMES DE SELS D'ETHERS ET D'ESTERS DE PROBUCOL FAIBLEMENT SOLUBLES
  申请人：ATHEROGENICS INC

  公开号：WO2004007423A1

  公开（公告）日：2004-01-22

  Organic amine salts of compounds of formula (I), and their pharmaceutically acceptable salts, and uses in medical therapy are provided.

  提供了公式（I）化合物的有机胺盐及其药用可接受的盐，并用于医学治疗。
• Apparatus And Methods For Delivering A Plurality Of Medicaments For Management Of Co-Morbid Diseases, Illnesses Or Conditions
  申请人：MILLER Frederick H.

  公开号：US20100221321A1

  公开（公告）日：2010-09-02

  A method and apparatus for delivering a plurality of medicaments in a single delivery vehicle for the management of co-morbid diseases, illnesses and conditions. The present invention provides a novel delivery process for many medicaments. Medicaments may be encapsulated and stored separately within a larger capsule until the time of ingestion, consumption, or the like. Benefits of the present invention include maintaining separation of distinct ingredients within a single capsule and the capability to control the time release of multiple ingredients within the capsule.

  一种用于管理共病疾病、疾病和病状的多种药物在单一输送装置中输送的方法和装置。本发明提供了一种新颖的多种药物输送过程。药物可以被封装并分别存储在更大的胶囊中，直到摄入、消耗或类似的时间。本发明的好处包括在单个胶囊中保持不同成分的分离以及控制胶囊中多种成分的时间释放的能力。
• [EN] VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS, ELOVANOID HYDROXYLATED DERIVATIVES, AND METHODS OF USE<br/>[FR] ACIDES GRAS POLYINSATURÉS À TRÈS LONGUE CHAÎNE, DÉRIVÉS HYDROXYLÉS D'ÉLOVANOÏDE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：UNIV LOUISIANA STATE

  公开号：WO2021046448A1

  公开（公告）日：2021-03-11

  This disclosure relates to methods of use related to omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFA) and their hydroxylated derivatives known as elovanoids to alleviate a symptom of, treat, or prevent disease. Furthermore, this invention is directed to compositions and methods for modulating VLC-PUFA bioactivity and availability.

  本公开涉及使用方法与ω-3非常长链多不饱和脂肪酸（n-3 VLC-PUFA）及其羟基化衍生物（称为elovanoids）缓解症状、治疗或预防疾病。此外，本发明还涉及调节VLC-PUFA生物活性和可用性的组合物和方法。
• BIOADHESIVE AND BIODEGRADABLE AND FORMULATIONS THAT PROVIDE SUSTAINED RELEASE OF ANTIMICROBIALS, BACTERIOPHAGES AND ANTI-INFLAMMATORY MEDICATIONS FOR INACTIVATION OF BIOFILMS AND THE TREATMENT OF RHINOSINUSITIS AND OTHER INFECTIONS
  申请人：Rhinotopic, LLC

  公开号：US20160022595A1

  公开（公告）日：2016-01-28

  Described is a composition comprising one or more active ingredients coated, dispersed, or dissolved with a mucoadhesive polymer. Although subject to multiple uses, the composition, in some embodiments, is usable for treating rhinosinusitis.

  描述了一种组合物，其中包含一个或多个活性成分，这些成分被涂覆、分散或溶解在黏膜粘附聚合物中。尽管可以用于多种用途，但在某些实施例中，该组合物可用于治疗鼻窦炎。