benzene sulfinic acid, NH4(1+) salt

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzene sulfinic acid, NH4(1+) salt
• 英文别名: ammonium benzenesulfinate；azane;benzenesulfinic acid
• 化学式: C₆H₅O₂S*H₄N
• 分子量: 159.209
• InChiKey: XLSIIHKGLGJRGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  60.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  benzene sulfinic acid, NH4(1+) salt 、 碘甲烷 在 氧气 作用下， 生成 苯磺酸甲酯
  参考文献：
  名称：

  Sugawara, M.; Baizer, M. M.; Monte, W. T., Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1983, vol. 37, # 6, p. 509 - 518

  摘要：

  DOI：

文献信息

• Process for removal of allyl group or allyloxycarbonyl group
  申请人：PFIZER INC.

  公开号：EP0676236A1

  公开（公告）日：1995-10-11

  This invention relates to a process for the removal of an allyl or allyloxycarbonyl group from an allyl or allyloxycarbonyl group protected compound (such as an allylic ester, carbonate, carbamate, O-allyl derivatives or N-allyl derivatives), which comprises contacting the allyl or allyloxycarbonyl group protected compound with a sulfinic acid compound, in the presence of a palladium catalyst in a reaction-inert solvent. Preferably, the sulfinic acid compound is represented by the formula:         X-SO₂M   (I) wherein X is C₁₋₂₀ alkyl, substituted C₁₋₂₀ alkyl (wherein the substituent(s) are independently halo, nitro, sulfo, oxo, amino, cyano, carboxy, hydroxy or moieties derived therefrom), phenyl, substituted phenyl (wherein the substituent(s) are independently C₁₋₃ alkyl, halo nitro, sulfo, oxo, amino, cyano, carboxy, hydroxy, acetamido or moieties derived therefrom), furyl or thienyl; and M is hydrogen, an alkali metal or ammonium salt residue. Of these, most preferred sulfinic acid compound is lithium p-toluenesulfinate, sodium p-toluenesulfinate, potassium p-toluenesulfinate, p-toluenesulfinic acid, ammonium p-toluenesulfinate, lithium benzenesulfinate, sodium benzenesulfinate, potassium benzenesulfinate, benzenesulfinic acid or ammonium benzenesulfinate. This invention is well suited to a process for the conversion of an allyl ester of 5R,6S-6-(1R-hydroxyethyl)-2-(1R-oxo-3S-thiolanylthio)-2-penem-3-carboxylic acid to 5R,6S-6-(1R-hydroxyethyl)-2-(1R-oxo-3S-thiolanylthio)-2-penem-3-carboxylic acid.

  本发明涉及一种从烯丙基或烯丙氧羰基保护的化合物（如烯丙基酯、碳酸酯、氨基甲酸酯、O-烯丙基衍生物或N-烯丙基衍生物）中去除烯丙基或烯丙氧羰基基团的方法，该方法包括在反应惰性溶剂中，在钯催化剂的存在下，将烯丙基或烯丙氧羰基保护的化合物与亚磺酸化合物接触。优选地，亚磺酸化合物具有以下通式：X-SO₂M (I)，其中X为C₁₋₂₀烷基、取代的C₁₋₂₀烷基（其中取代基独立地为卤素、硝基、磺基、氧代、氨基、氰基、羧基、羟基或由此衍生的基团）、苯基、取代的苯基（其中取代基独立地为C₁₋₃烷基、卤素、硝基、磺基、氧代、氨基、氰基、羧基、羟基、乙酰氨基或由此衍生的基团）、呋喃基或噻吩基；M为氢、碱金属或铵盐残基。其中，最优选的亚磺酸化合物为锂对甲苯亚磺酸、钠对甲苯亚磺酸、钾对甲苯亚磺酸、对甲苯亚磺酸、铵对甲苯亚磺酸、锂苯亚磺酸、钠苯亚磺酸、钾苯亚磺酸、苯亚磺酸或铵苯亚磺酸。本发明特别适用于将5R,6S-6-(1R-羟乙基)-2-(1R-氧代-3S-硫杂环己硫基)-2-青霉烯-3-羧酸的烯丙基酯转化为5R,6S-6-(1R-羟乙基)-2-(1R-氧代-3S-硫杂环己硫基)-2-青霉烯-3-羧酸的过程。
• Reaction-Curable Adhesive Composition and Dental Adhesive Kit
  申请人：Yamamoto Takashi

  公开号：US20100292359A1

  公开（公告）日：2010-11-18

  A reaction-curable adhesive composition exhibiting acidity is formed form a weakly acidic to alkaline composition (I) comprising (a) a polymerizable monomer and (b) a compound represented by the following formula (1) and a strongly acidic composition (II) comprising (a) a polymerizable monomer. R 1 —C 6 H 4 —NR 2 CH 2 COOR 3 (1) wherein R 1 and R 2 are each independently a hydrogen atom or an alkyl group which may have a functional group, and R 3 is a hydrogen atom or a metal atom. The composition containing the polymerizable monomer can be stably stored for a long period of time.

  一种表现出酸性的反应固化粘合剂组合物是由一个弱酸性至碱性的组合物(I)和一个强酸性的组合物(II)形成的。组合物(I)包括(a)可聚合单体和(b)由以下式子(1)表示的化合物，而组合物(II)包括(a)可聚合单体。R1—C6H4—NR2CH2COOR3(1)，其中R1和R2各自独立地是氢原子或可能具有功能基团的烷基基团，而R3是氢原子或金属原子。含有可聚合单体的组合物可以稳定地储存长时间。
• Acrylate compound and composition containing the same
  申请人：TOKUYAMA SODA KABUSHIKI KAISHA

  公开号：EP0206810A2

  公开（公告）日：1986-12-30

  Disclosed is an acrylate compound represented by the following general formula: wherein R1 stands for a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R2 stands for an alkylene group having 2 to 20 carbon atoms, R3 stands for hydrogen atom or an alkyl group having 1 to 20 carbon atoms when n is 1, and n is 1 or 2 and adhesive compositions comprising this acrylate compound.

  本发明公开了一种由以下通式表示的丙烯酸酯化合物： 其中 R1 代表氢原子或具有 1 至 4 个碳原子的烷基，R2 代表具有 2 至 20 个碳原子的亚烷基，R3 代表氢原子或具有 1 至 20 个碳原子的烷基，当 n 为 1 时，n 为 1 或 2，以及包含这种丙烯酸酯化合物的粘合剂组合物。
• Adhesives for ceramics and processes for the bonding of ceramics using same
  申请人：MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0252603A2

  公开（公告）日：1988-01-13

  Adhesives for ceramics obtained as first adhesives for ceramics according to the invention are excellent in bond properties as well as in water resistance because they contain first acidic compounds such as organic carboxylic acids in addition to silane coupling agents, polymerizable monomers and polymerization catalysts. Further, adhesives for ceramics obtained as second adhesives for ceramics according to the invention are excellent in bond properties as well as in dependability and water resistance because they contain metal salts in addition to silane coupling agents, polymerizable monomers and polymerization catalysts. Furthermore, adhesives for ceramics obtained as third adhesives for ceramics according to the invention are excellent in bond properties as well as dependability and water resistance because they contain second acidic compounds selected from among metal salts and organic carboxylic acid anhydrides in addition to silane coupling agents, polymerizable monomers and polymerization catalysts.

  根据本发明作为陶瓷用第一粘合剂获得的陶瓷用粘合剂具有优异的粘合性能和耐水性，这是因为除了硅烷偶联剂、可聚合单体和聚合催化剂之外，它们还含有第一酸性化合物，如有机羧酸。此外，根据本发明作为陶瓷用第二粘合剂获得的陶瓷用粘合剂在粘合性能、可靠性和耐水性方面都非常出色，因为除了硅烷偶联剂、可聚合单体和聚合催化剂外，它们还含有金属盐。此外，根据本发明作为陶瓷用第三粘合剂获得的陶瓷用粘合剂在粘合性能、可靠性和耐水性方面都非常出色，因为它们除了含有硅烷偶联剂、可聚合单体和聚合催化剂外，还含有选自金属盐和有机羧酸酸酐的第二酸性化合物。
• Dental adhesive composition
  申请人：MITSUBISHI RAYON CO., LTD.

  公开号：EP0347711A2

  公开（公告）日：1989-12-27

  A dental adhesive composition containing as major components: (a) at least one isocyanate-group-containing urethane prepolymer, (b) at least one isocyanate-group-containing silane compound, (c) at least one radical-polymerizable unsaturated monomer, and (d) at least one initiator selected from the group consisting of redox polymerization initiators and photopolymerization initiators is disclosed. This composition is excellent in bonding properties when it is used to bond a living dental tissue with a restoring material such as a metal, organic polymer, and ceramic. Also, this adhesive composition does not require a troublesome pretreatment of the restoring material with an etching agent such as phosphoric acid when the restorating material is required to bond to the living tissue.

  一种牙科粘合剂组合物，其主要成分包括 (a) 至少一种含异氰酸酯基的聚氨酯预聚物、 (b) 至少一种含异氰酸酯基团的硅烷化合物、 (c) 至少一种可自由基聚合的不饱和单体，以及 (d) 至少一种从氧化还原聚合引发剂和光聚合引发剂组成的组中选出的引发剂。 的组中选出的一种引发剂。 当这种组合物用于粘接活体牙科组织和修复材料（如金属、有机聚合物和陶瓷）时，具有优异的粘接性能。此外，当修复材料需要与活体组织粘合时，这种粘合剂组合物不需要用磷酸等腐蚀剂对修复材料进行麻烦的预处理。