Benzyl-methansulfinat | 35896-44-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl-methansulfinat
• 英文别名: Benzyl methanesulfinate
• CAS: 35896-44-7
• 化学式: C₈H₁₀O₂S
• 分子量: 170.232
• InChiKey: NWXWAUCSADGOBG-UHFFFAOYSA-N

物化性质

• 沸点：
  291.6±33.0 °C(Predicted)
• 密度：
  1.232±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  45.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-(benzylsulfonyl)pyridine 以 乙醇 为溶剂， 反应 0.25h， 生成 Benzyl-methansulfinat
  参考文献：
  名称：

  A Convenient Preparation of Sulfinic Acids by the Reaction of 2-Sulfonylpyridines and Their N-Oxides with Nucleophiles

  摘要：

  DOI：

  10.3987/r-1986-11-3019

文献信息

• Organic sulfur chemistry. 29. Use of the trimethylsilyl group in synthesis. Preparation of sulfinate esters and unsymmetrical disulfides
  作者：David N. Harpp、Barry T. Friedlander、Charles Larsen、Kosta Steliou、Alan Stockton

  DOI：10.1021/jo00412a013

  日期：1978.9
• Kondratenko,N.V. et al., Journal of Organic Chemistry USSR (English Translation), 1971, vol. 7, p. 2473 - 2479
  作者：Kondratenko,N.V. et al.

  DOI：——

  日期：——
• BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF
  申请人：SONG Soo-Chang

  公开号：US20120121517A1

  公开（公告）日：2012-05-17

  The present invention relates to a poly(organophosphazene)-superparamagnetic nanoparticle complex including a biodegradable and thermosensitive poly(organophosphazene) and a iron oxide (Fe 3 O 4 , Magnetite)-series ferrite superparamagnetic nanoparticle, a preparation method, and uses of carrying a physiologically-active material, a bio-material and a biomaterial for cancer hyperthermia. The iron oxide is used as a MRI contrast agent for T- 2 and T 2 * weighted image, and the poly(organophosphazene) shows a sol-to-gel behavior depending upon the temperature change. The complex is a bound-type where the superparamagnetic ferrite nanoparticle is bonded to phosphazene-based polymer via hydrophobic binding, and a mixed-type where the superparamagnetic ferrite nanoparticle is physically mixed with the phosphazene-based polymer.
• POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF
  申请人：SONG Soo-Chang

  公开号：US20140031289A1

  公开（公告）日：2014-01-30

  The present invention relates to a thermosensitive phosphazene-based polymer having a degradation controllable ionic group, a use thereof, and a use thereof as a material for delivering bioactive substances. The phosphazene-based polymer according to the present invention has the thermosensitivity of showing the temperature-dependent sol-gel phase transition. Thus, it forms a gel phase at the body temperature when it is injected into the body to make it easy to control the release of bioactive substances such as drugs, and has the functional groups capable of making chemical bonds such as ionic bond, covalent bond, coordinate bond, etc. with drugs and thus is excellent in bearing the drugs. Since it can control the degradation rate depending on the kind of ionic group, it can selectively control the release time depending on the characteristics of drugs. Furthermore, it has an excellent biocompatibility and thus is very useful as a material for delivery of bioactive substances such as drugs, etc.
• US9017726B2
  申请人：——

  公开号：US9017726B2

  公开（公告）日：2015-04-28