chloromethylenedimethylammonium chloride | 149409-22-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: chloromethylenedimethylammonium chloride
• 英文别名: chloromethylene dimethyl-ammonium chloride；(Chloromethyl)dimethylamine hydrochloride；1-chloro-N,N-dimethylmethanamine;hydrochloride
• CAS: 149409-22-3
• 化学式: C₃H₉ClN*Cl
• 分子量: 130.017
• InChiKey: SINIMGUHLRMHMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.17
• 重原子数：
  6
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  4.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  chloromethylenedimethylammonium chloride 、 dimethylmaleate(1,10-phenanthroline)platinum 以 硝基甲烷 为溶剂， 以80%的产率得到[PtCl(CHNMe2)(1,10-phenanthroline)]Cl
  参考文献：
  名称：

  First Coordinatively Saturated Carbene Complexes of Platinum(II):  Synthesis, Structure, and Reactivity

  摘要：

  Coordinatively saturated carbene complexes of platinum(II) have been obtained by oxidative addition of [ClCH=NMe2]Cl to Pt(0) precursors. The cationic products of general formula [PtCl(CHNMe2)(N,N-chelate)(olefin)]Cl have been characterized through NMR spectroscopy and for [PtCl(CHNMe2)(2,9-Me-2-1,10-phen)(Z-MeO2CCH=CHCO2Me)]Cl by X-ray diffractometry. The latter species reacts with nucleophiles affording dimethylformamide and the corresponding Pt(0) precursor [Pt(2,9-Me-2-1,10-phen)(Z-MeO2CCH=CHCO2Me)]. Attempts to obtain related complexes containing carbene groups Pt=CHY without a heteroatom in alpha-position (Y = CO2Et, CO2NMe2, CN) have led to the isolation of complexes of formula [PtR(dmphen){eta(1),eta(2)-CH(Y)O2CCH=CHCO2Me}] (R = Me, Ph), Formally derived fi om an intrasnolecular nucleophilic addition to a carbene intermediate. The X-ray structure of a representative product, [PtMe(dmphen){eta(1),eta(2)-CH(CO2Et)O2CCH=CHCO2Me}], is reported.

  DOI：

  10.1021/om990240r
• 作为试剂：
  描述：

  去氢胆酸 在 吡啶 、 chloromethylenedimethylammonium chloride 、 lithium tri(t-butoxy)aluminum hydride 作用下， 生成 dehydrocholic aldehyde
  参考文献：
  名称：

  在新合成的β-内酰胺衍生物中使用甾族醛

  摘要：

  在本文中，描述了包含类固醇和β-内酰胺单元的β-内酰胺类固醇产物4。产物4通过Ugi反应容易地一步制备。描述了合成脱氢胆醛的中等规模的高产率方法。

  DOI：

  10.1016/0040-4020(95)00541-f

文献信息

• 含N杂环季铵盐阳离子型防膨粘土稳定剂及 其合成方法
  申请人：中国石油化工股份有限公司

  公开号：CN106866506B

  公开（公告）日：2019-08-13

  本发明属于油田开发技术领域，具体涉及含N杂环季铵盐阳离子型防膨粘土稳定剂及其合成方法，该粘土稳定剂是由萘酐与正十二醇反应生成十二烷基萘酐半酯，然后与N,N‑二甲氨基氯甲烷通过溶液聚合反应生成中间体，最后再与2‑溴甲基吡啶反应生成，其中萘酐、正十二醇、N,N‑二甲氨基氯甲烷和2‑溴甲基吡啶的摩尔比为1:1～1.6:1.1～1.5:0.8～1.7，优选为1:1.1:1.2:1.5。本发明的粘土稳定剂的原料来源广泛、合成工艺简单、用量少、油藏适应性强的特点；本发明的粘土稳定剂耐温耐盐性能好，能耐温达到220℃，耐矿化度达到220000mg/L，且具有良好的配伍性；本发明的粘土稳定剂可强烈的吸附到粘土表面，不易分解，粘土稳定剂有效期长，防膨率高，防膨率达到98％以上。
• First Coordinatively Saturated Carbene Complexes of Platinum(II):  Synthesis, Structure, and Reactivity
  作者：Maria E. Cucciolito、Achille Panunzi、Francesco Ruffo、Vincenzo G. Albano、Magda Monari

  DOI：10.1021/om990240r

  日期：1999.8.1

  Coordinatively saturated carbene complexes of platinum(II) have been obtained by oxidative addition of [ClCH=NMe2]Cl to Pt(0) precursors. The cationic products of general formula [PtCl(CHNMe2)(N,N-chelate)(olefin)]Cl have been characterized through NMR spectroscopy and for [PtCl(CHNMe2)(2,9-Me-2-1,10-phen)(Z-MeO2CCH=CHCO2Me)]Cl by X-ray diffractometry. The latter species reacts with nucleophiles affording dimethylformamide and the corresponding Pt(0) precursor [Pt(2,9-Me-2-1,10-phen)(Z-MeO2CCH=CHCO2Me)]. Attempts to obtain related complexes containing carbene groups Pt=CHY without a heteroatom in alpha-position (Y = CO2Et, CO2NMe2, CN) have led to the isolation of complexes of formula [PtR(dmphen)eta(1),eta(2)-CH(Y)O2CCH=CHCO2Me}] (R = Me, Ph), Formally derived fi om an intrasnolecular nucleophilic addition to a carbene intermediate. The X-ray structure of a representative product, [PtMe(dmphen)eta(1),eta(2)-CH(CO2Et)O2CCH=CHCO2Me}], is reported.