methoxymethyl-phenylphosphinic acid | 356589-11-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methoxymethyl-phenylphosphinic acid
• 英文别名: Methoxymethyl(phenyl)phosphinic acid
• CAS: 356589-11-2
• 化学式: C₈H₁₁O₃P
• 分子量: 186.147
• InChiKey: ZCCMVNCQOGSAJU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯膦酸 、 甲氧基乙酸 在 甲烷磺酸 、 四磷十氧化物 作用下， 反应 2.5h， 生成 methoxymethyl-phenylphosphinic acid
  参考文献：
  名称：

  [EN] METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN a-OXY PHOSPHORUS GROUP
  [FR] PROCÉDÉ POUR LA FABRICATION DE COMPOSÉS CONTENANT UN GROUPE ?-OXY-PHOSPHORÉ

  摘要：

  披露了一种含有α-氧磷基团的化合物的制造方法。将至少含有一个P-O-P基团的P-O组分，其中至少一个磷处于+3氧化态，按特定比例添加到含有α-氧羧酸基团的化合物中，然后进行反应并在随后加入水。随后可以回收形成的含有α-氧磷基团的化合物。

  公开号：

  WO2012098255A1

文献信息

• Method for the manufacture of compounds containing an alpha-oxyphosphorus group by using an activator
  申请人：Straitmark Holding AG

  公开号：EP2567961A1

  公开（公告）日：2013-03-13

  A method for the manufacture of compounds containing an α-oxy phosphorus group is disclosed. A compound containing an α-oxy carboxylic acid group is reacted in a specific equivalent ratio with a nucleophilic P component, wherein the phosphorus atom has the oxidation state +1 or +3, whereby the compound containing an α-oxy carboxylic acid group or the nucleophilic P component or both are first reacted with an activator, followed by conducting the reaction and adding a water at the end of the reaction. The compounds containing an α-oxy phosphorus group formed are then recovered.

  揭示了一种制备含有α-氧磷基团的化合物的方法。将含有α-氧羧酸基团的化合物与亲核P组分以特定当量比反应，其中磷原子的氧化态为+1或+3，从而使含有α-氧羧酸基团的化合物或亲核P组分或两者之一首先与活化剂发生反应，然后进行反应并在反应结束时加入水。然后回收形成的含有α-氧磷基团的化合物。
• METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN alpha-OXY PHOSPHORUS GROUP
  申请人：Straitmark Holding AG

  公开号：EP2665734B1

  公开（公告）日：2016-06-29
• METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN ALPHA-OXYPHOSPHORUS GROUP BY USING AN ACTIVATOR
  申请人：Straitmark Holding AG

  公开号：EP2753625B1

  公开（公告）日：2017-08-02
• [EN] METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN ALPHA-OXYPHOSPHORUS GROUP BY USING AN ACTIVATOR<br/>[FR] PROCÉDÉ DE FABRICATION DE COMPOSÉS CONTENANT UN GROUPE ALPHA-OXYPHOSPORE À L'AIDE D'UN ACTIVATEUR
  申请人：STRAITMARK HOLDING AG

  公开号：WO2013034730A2

  公开（公告）日：2013-03-14

  A method for the manufacture of compounds containing an a-oxy phosphorus group is disclosed. A compound containing an a-oxy carboxylic acid group is reacted in a specific equivalent ratio with a nucleophilic P component, wherein the phosphorus atom has the oxidation state +1 or +3, whereby the compound containing an a-oxy carboxylic acid group or the nucleophilic P component or both are first reacted with an activator, followed by conducting the reaction and adding a water at the end of the reaction. The compounds containing an a-oxy phosphorus group formed are then recovered.
• [EN] METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN a-OXY PHOSPHORUS GROUP<br/>[FR] PROCÉDÉ POUR LA FABRICATION DE COMPOSÉS CONTENANT UN GROUPE ?-OXY-PHOSPHORÉ
  申请人：STRAITMARK HOLDING AG

  公开号：WO2012098255A1

  公开（公告）日：2012-07-26

  A method for the manufacture of compounds containing an α-oxy phosphorus group is disclosed. A P-O component having at least one P-O-P moiety, whereby at least one phosphorus has the +3 oxidation state, is added in specific proportions to a compound containing an α-oxy carboxylic acid group, followed by conducting the reaction and adding water subsequently. The compounds containing an α-oxy phosphorus group formed can then be recovered.

  披露了一种含有α-氧磷基团的化合物的制造方法。将至少含有一个P-O-P基团的P-O组分，其中至少一个磷处于+3氧化态，按特定比例添加到含有α-氧羧酸基团的化合物中，然后进行反应并在随后加入水。随后可以回收形成的含有α-氧磷基团的化合物。