(Propylsulfanyl)cyclopropane | 88016-27-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (Propylsulfanyl)cyclopropane
• 英文别名: propylsulfanylcyclopropane
• CAS: 88016-27-7
• 化学式: C₆H₁₂S
• 分子量: 116.227
• InChiKey: HCUGKHTZTOJZGY-UHFFFAOYSA-N

物化性质

• 沸点：
  65 °C(Press: 58 Torr)
• 密度：
  0.94±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  cyclopropyllithium 、 二丙基二硫 以 乙醚 为溶剂， 反应 2.0h， 以52%的产率得到(Propylsulfanyl)cyclopropane
  参考文献：
  名称：

  Cyclopropyl organyl sulfides

  摘要：

  DOI：

  10.1007/bf00954373

文献信息

• [EN] 2-OXO-2,3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS<br/>[FR] 2-OXO-2,3-DIHYDRO-INDOLES DESTINÉS AU TRAITEMENT DE TROUBLES DU SNC
  申请人：HOFFMANN LA ROCHE

  公开号：WO2014040969A1

  公开（公告）日：2014-03-20

  The present invention is concerned with 2-oxo-2,3-dihydro-indoles of general formula (I) wherein (N1) is phenyl or a heteroaryl group, selected from pyridinyl, pyrimidinyl, imidazolyl, isoxazolyl or pyrazolyl; (N2) is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be on all free positions; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, lower alkoxy or halogen; n is 1 or 2; if n is 2, R1 may be the same or not; R2/R2' are independently from each other lower alkyl, or form together with the carbon atom to which they are attached a C3-6-cycloalkyl ring; R3 is lower alkyl, C3-6-cycloalkyl, CH2-C3-6-cycloalkyl, C3-6-cycloalkyl wherein one ring-carbon atom is replaced by -O-, (CH2)3-O-C3-6-cycloalkyl, lower alkyl substituted by hydroxy, lower alkyl substituted by halogen, (CH2)3-S(O)2-C3-6-cycloalkyl or (CH2)2-S(O)2-lower alkyl; R4 is hydrogen, halogen or lower alkyl; m is 1 or 2; if m is 2, R4 may be the same or not; as well as with a pharmaceutically acceptable salts thereof, with a racemic mixture, or with its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.

  本发明涉及一般式(I)的2-氧代-2,3-二氢吲哚，其中（N1）是苯基或杂环芳基，选择自吡啶基、嘧啶基、咪唑基、异噁唑基或吡唑基；（N2）是苯基或吡啶基，其中吡啶基中的N原子可以在所有自由位置上；R1是氢、低碳基、被卤素取代的低碳基、低烷氧基或卤素；n为1或2；若n为2，则R1可以相同也可以不同；R2/R2'彼此独立地为低碳基，或与它们连接的碳原子一起形成一个C3-6环烷基环；R3是低碳基、C3-6环烷基、CH2-C3-6环烷基、C3-6环烷基其中一个环碳原子被-O-取代、（ ）3-O-C3-6环烷基、被羟基取代的低碳基、被卤素取代的低碳基、（ ）3-S(O)2-C3-6环烷基或（ ）2-S(O)2-低碳基；R4是氢、卤素或低碳基；m为1或2；若m为2，则R4可以相同也可以不同；以及其药学上可接受的盐、消旋混合物、或其对应的对映体和/或光学异构体和/或立体异构体。
• [EN] CYCLOHEXENONE OXIME ETHERS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：WO1993016033A1

  公开（公告）日：1993-08-19

  (DE) Cyclohexenonoximether (I) (R1 = Alkyl; W = geg. substituierte Alkylenkette; X = NO2, CN, Halogen, Alkyl, Halogenalkyl; n = 2 - 3 oder 2 - 5 für den Fall, daß alle X Halogen bedeuten; R2 = Alkoxyalkyl, Alkylthioalkyl, geg. subst. Cycloalkyl, geg. subst. Cycloalkenyl, geg. subst. 5-gliedriger gesättigter Heterocyclus; geg. subst. 6- oder 7-gliedriger Heterocyclus; geg. subst. 5-gliedriger Heteroaromat; geg. subst. Phenyl oder Pyridyl), Verfahren zu ihrer Herstellung und ihre Verwendung.(EN) The invention concerns cyclohexenone oxime ethers of formula (I), in which R1 = alkyl; W = an optionally substituted alkylene chain; X = NO2, CN, halogen, alkyl or haloalkyl; n = 2 to 3, or 2 to 5 if all the X substituents are halogens; R2 = alkoxyalkyl, alkylthioalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, an optionally substituted saturated 5-membered heterocyclic ring, an optionally substituted 6 or 7-membered heterocyclic ring, an optionally substituted aromatic 5-membered heterocyclic ring or an optionally substituted phenyl or pyridyl group. The invention also concerns methods for the preparation of such ethers and their use.(FR) Ethers de cyclohexenone-oximes de formule (I) dans laquelle R1 = alkyle; W = chaîne d'alkyles éventuellement substitués; X = NO2, CN, halogène, alkyle, halogénoalkyle; n = 2-3 ou 2-5 dans le cas où tous les X représentent l'halogène; R2 = alcoxyalkyle, alkylthioalkyle, cycloalkyle éventuellement substitué; cycloalkényle éventuellement substitué; hétérocycle saturé à 5 chaînons éventuellement substitué; hétérocycle à 6 ou 7 chaînons éventuellement substitué; hétéroaromate à 5 chaînons éventuellement substitué; phényle ou pyridyle éventuellement substitué. Procédé de fabrication et utilisation.

  该发明涉及环己烯酮橙 then 酚醚基团 (I)，其中 R1 为烷基；W 为可选基团的烷基链；X 为 NO2、CN、卤素、烷基或卤素烷基；n 为 2 至 3，或 2 至 5（当所有 X 为卤素时）；R2 为醚烷基、硫醚烷基、可选环烷基、可选环烯基、可选含饱和 5 员 hetero环、可选 6 或 7 边 hetero环、可选含饱和的 5 员 hetero环、或可选苯或吡啶基。该发明还涉及制备这种醚的方法及其用途。
• [DE] SUBSTITUIERTE 2-ARYLPYRIDINE ALS HERBIZIDE<br/>[EN] SUBSTITUTED 2-ARYLPYRIDINE AS HERBICIDE<br/>[FR] ARYLPYRIDINE SUBSTITUEE EN 2 UTILISEE COMME HERBICIDE
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：WO1998007720A1

  公开（公告）日：1998-02-26

  (DE) Substituierte 2-Arylpyridine (I) und deren Salze, wobei R1 = SH, SO2OH, SO2C1, SO2NH2, C1-C6-Alkylthio, C1-C6-Alkylsulfinyl, C1-C6-Alkylsulfonyl, C1-C6-Alkylaminosulfonyl, Di(C1-C6-alkyl)aminosulfonyl; R2, R3 = H, Halogen; R4 = H, C1-C6-Alkyl, C1-C6-Halogenalkyl, Cyano-C1-C6-alkyl, C1-C6-Alkoxy, C1-C6-Alkoxy-C1-C6-alkyl, C1-C4-Halogenalkoxy-C1-C4-alkyl, C1-C6-Alkylthio-C1-C6-alkyl, C1-C6-Alkylsulfinyl-C1-C6-alkyl, C1-C6-Alkylsulfonyl-C1-C6-alkyl, C1-C4-Alkoxy-C1-C4-alkoxy-C1-C4-alkyl, C1-C6-Alkoxycarbonyl-C1-C6-alkyl, C1-C3-Alkoxy-C1-C3-alkoxycarbonyl-C1-C6-alkyl, C2-C4-Alkenyloxy-C1-C4-alkyl, C3-C4-Alkinyloxy-C1-C4-alkyl, C3-C7-Cycloalkyl, C3-C7-Cycloalkyl-C1-C6-alkyl, C3-C7-Cycloalkyloxy-C1-C6-alkyl, C3-C7-Cycloalkylthio-C1-C6-alkyl, C3-C8-Alkenyl, C3-C8-Alkinyl, C3-C8-Halogenalkenyl, C3-C8-Halogenalkinyl, C1-C6-Alkoxy-C3-C8-alkenyl, C1-C6-alkoxy-C3-C8-alkinyl, C1-C6-Alkylcarbonyl, C1-C6-Alkylsulfonyl, C3-C6-Alkenyloxy, C3-C6-Alkinyloxy oder geg. subst. Benzyl; X = -O-, -S-, -NH-, -N(CH3)-, -CH2-; Y = chemische Bindung, -CO-, C(R5,R6); R5,R6 = H, NO2, CN, OCH3, SCH3, Halogen, C1-C4-Alkyl, C1-C4-Halogenalkyl, C1-C4-Alkoxycarbonyl, C2-C6-Alkenyl, C3-C6-Alkinyl, C1-C4-Alkoxycarbonyl-C1-C4-alkyl. Verwendung: als Herbizide; zur Desikkation/Defoliation von Pflanzen.(EN) Substituted 2-arylpyridine of formula (I) and salts thereof. In said formula (I), R1 = SH, SO2OH, SO2C1, SO2NH2, C1-C6-Alkylthio, C1-C6-Alkyl sulfinyl, C1-C6-alkylsulfonyl, C1-C6-alkylamino-sulfonyl, Di(C1-C6-alkyl)aminosulfonyl; R2, R3 = H, halogen; R4 = H, C1-C6-alkyl, C1-C6-halogenalkyl, cyano-C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkoxy-C1-C6-alkyl, C1-C4-halogen-alkoxy-C1-C4-alkyl, C1-C6-alkylthio-C1-C6-alkyl, C1-C6 alkyl sulfinyl-C1-C6-alkyl, C1-C6-alkylsulfonyl-C1-C6-alkyl, C1-C4-alkoxy-C1-C4-alkoxy-C1-C4-alkyl, C1-C6-alkoxycarbonyl-C1-C6-alkyl, C1-C3-alkoxy-C1-C3-alkoxycarbonyl-C1-C6-alkyl, C2-C4-alkenyloxy-C1-C4-alkyl, C3-C4-alkinyloxy-C1-C4-alkyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C6-alkyl, C3-C7-cycloalkyloxy-C1-C6-alkyl, C3-C7-cycloalkylthio-C1-C6-alkyl, C3-C8-alkenyl, C3-C8-alkinyl, C3-C8-halogenalkenyl, C3-C8-halogenalkinyl, C1-C6-alkoxy-C3-C8-alkenyl, C1-C6-alkoxy-C3-C8-alkinyl, C1-C6-alkylcarbonyl, C1-C6-alkylsulfonyl, C3-C6-alkenyloxy, C3-C6-alkinyloxy or eventually substituted benzyl; X = -O-, -S-, -NH-, -N(CH3)-, -CH2-; Y = chemical bond, -CO-, C(R5,R6); R5,R6 = H, NO2, CN, OCH3, SCH3, halogen, C1-C4-alkyl, C1-C4-halogenalkyl, C1-C4-alkoxycarbonyl, C2-C6-alkenyl, C3-C6-alkinyl, C1-C4-alkoxycarbonyl-C1-C4-alkyl. Application as herbicide; for plant desiccation/defoliation.(FR) Arylpyridine substituée en 2 répondant à la formule (I) et ses sels. Dans ladite formule (I), R1 = SH, SO2OH, SO2C1, SO2NH2, C1-C6-Alkylthio, C1-C6-Alkyle sulfinyle, C1-C6-alkylsulfonyle, C1-C6-alkylamino-sulfonyle, Di(C1-C6-alkyl)aminosulfonyle; R2, R3 = H, halogène; R4 = H, C1-C6-alkyle, C1-C6-halogenalkyle, cyano-C1-C6-alkyle, C1-C6-alkoxy, C1-C6-alkoxy-C1-C6-alkyle, C1-C4-halogène-alkoxy-C1-C4-alkyle, C1-C6-alkylthio-C1-C6-alkyle-, C1-C6-alkylsulfinyle-C1-C6-alkyle, C1-C6-alkylsulfonyl-C1-C6 alkyle, C1-C4-alkoxy-C1-C4-alkoxy-C1-C4-alkyle, C1-C6-alkoxycarbonyle-C1-C6-alkyle, C1-C3-alkoxy-C1-C3-alkoxycarbonyl-C1-C6-alkyle, C2-C4-alkenyloxy-C1-C4-alkyle, C3-C4-alkinyloxy-C1-C4-alkyle, C3-C7-cycloalkyle, C3-C7-cycloalkyl-C1-C6-alkyle, C3-C7-cycloalkyloxy-C1-C6-alkyle, C3-C7-cycloalkylthio-C1-C6-alkyle, C3-C8-alkenyle, C3-C8-alkinyle, C3-C8-halogenalkenyle, C3-C8-halogenalkinyle, C1-C6-alkoxy-C3-C8-alkenyle, C1-C6-alkoxy-C3-C8-alkinyle, C1-C6-alkylcarbonyle, C1-C6-alkylsulfonyle, C3-C6-alkenyloxy, C3-C6-alkinyloxy ou benzyl éventuellement substitué; X = -O-, -S-, -NH-, -N(CH3)-, -CH2-; Y = liaison chimique, -CO-, C(R5,R6); R5,R6 = H, NO2, CN, OCH3, SCH3, halogène, C1-C4-alkyle, C1-C4-halogenalkyle, C1-C4-alkoxycarbonyle, C2-C6-alkenyle, C3-C6-alkinyle, C1-C4-alkoxycarbonyl-C1-C4-alkyle. Application: comme herbicide; pour la dessication/défoliation des plantes.

  ( DE ) Substituierte 2-Arylpyridine ( I ) und deren Salze , wobei R1 = SH , SO2OH , SO2C1 , SO2NH2 , C1-C6-Alkylthio , C1-C6-Alkylsulfinyl , C1-C6-Alkylsulfonyl , C1-C6-Alkylaminosulfonyl , Di(C1-C6-alkyl)aminosulfonyl ; R2 , R3 = H , Halogen ; R4 = H , C1-C6-Alkyl , C1-C6-Halogenalkyl , Cyano-C1-C6-alkyl , C1-C6-Alkoxy , C1-C6-Alkoxy-C1-C6-alkyl , C1-C4-Halogenalkoxy-C1-C4-alkyl , C1-C6-Alkylthio-C1-C6-alkyl , C1-C6-Alkylsulfinyl-C1-C6-alkyl , C1-C6-Alkylsulfonyl-C1-C6-alkyl , C1-C4-Alkoxy-C1-C4-alkoxy-C1-C4-alkyl , C1-C6-Alkoxycarbonyl-C1-C6-alkyl , C1-C3-Alkoxy-C1-C3-alkoxycarbonyl-C1-C6-alkyl , C2-C4-Alkenyloxy-C1-C4-alkyl , C3-C4-Alkinyloxy-C1-C4-alkyl , C3-C7-Cycloalkyl , C3-C7-Cycloalkyl-C1-C6-alkyl , C3-C7-Cycloalkyloxy-C1-C6-alkyl , C3-C7-Cycloalkylthio-C1-C6-alkyl , C3-C8-Alkenyl , C3-C8-Alkinyl , C3-C8-Halogenalkenyl , C3-C8-Halogenalkinyl , C1-C6-Alkoxy-C3-C8-Alkenyl , C1-C6-Alkoxy-C3-C8-Alkinyl , C1-C6-Alkylcarbonyl , C1-C6-Alkylsulfonyl , C3-C6-Alkenyloxy , C3-C6-Alkinyloxy oder geg. substit. Benzyl ; X = -O- , -S- , -NH- , -N(CH3)- , -CH2- ; Y = chemische Bindung , -CO- , C(R5,R6) ; R5,R6 = H , NO2 , CN , OCH3 , SCH3 , Halogen , C1-C4-Alkyl , C1-C4-Halogenalkyl , C1-C4-Alkoxycarbonyl , C2-C6-Alkenyl , C3-C6-Alkinyl , C1-C4-Alkoxycarbonyl-C1-C4-alkyl. Benutzung: als Herbicide ; zur Entsechung/Ent.Decimalisierung von Pflanzen. ( EN ) Substituted 2-arylpyridine of formula ( I ) and its salts. In formula ( I ), R1 = SH , SO2OH , SO2C1 , SO2NH2 , C1-C6-alkylthio , C1-C6-alkyl sulfinyl , C1-C6-alkylsulfonyl , C1-C6-alkylaminosulfonyl , Di(C1-C6-alkyl)aminosulfonyl ; R2 , R3 = H , halogen ; R4 = H , C1-C6-alkyl , C1-C6-halogenalkyl , cyano-C1-C6-alkyl , C1-C6-alkoxy , C1-C6-alkoxy-C1-C6-alkyl , C1-C4-halogen-alkoxy-C1-C4-alkyl , C1-C6-alkylthio-C1-C6-alkyl , C1-C6-alkylsulfinyl-C1-C6-alkyl , C1-C6-alkylsulfonyl-C1-C6-alkyl , C1-C4-alkoxy-C1-C4-alkoxy-C1-C4-alkyl , C1-C6-alkoxycarbonyl-C1-C6-alkyl , C1-C3-alkoxy-C1-C3-alkoxycarbonyl-C1-C6-alkyl , C2-C4-alkenyloxy-C1-C4-alkyl , C3-C4-alkinyloxy-C1-C4-alkyl , C3-C7-cycloalkyl , C3-C7-cycloalkyl-C1-C6-alkyl , C3-C7-cycloalkyloxy-C1-C6-alkyl , C3-C7-cycloalkylthio-C1-C6-alkyl , C3-C8-alkenyl , C3-C8-alkinyl , C3-C8-halogenalkenyl , C3-C8-halogenalkinyl , 1-C6-alkoxy-C3-C8-alkenyl , 1-C6-alkoxy-C3-C8-alkinyl , 1-C6-alkylcarbonyle , 1-C6-alkylsulfonyl , C3-C6-alkenyloxy , C3-C6-alkinyloxy or eventually substitute benzyl ; X = -O- , -S- , -NH- , -N(CH3)- , -CH2- ; Y = chemical bond , -CO- , C(R5,R6) ; R5,R6 = H , NO2 , CN , OCH3 , SCH3 , halogen , C1-C4-alkyl , C1-C4-halogenalkyl , C1-C4-alkoxycarbonyl , C2-C6-alkenyl , C3-C6-alkinyl , C1-C4-alkoxycarbonyl-C1-C4-alkyl. Application: as herbicide ; for plant desiccation/defoliation.
• BOPOHKOB, M. G.;NIKOLSKIJ, N. S., IZV. AN CCCP. CEP. XIM., 1983, N 7, 1664-1667
  作者：BOPOHKOB, M. G.、NIKOLSKIJ, N. S.

  DOI：——

  日期：——
• PROCESS FOR PRODUCING POLYDIENES
  申请人：Bridgestone Corporation

  公开号：EP2825574A1

  公开（公告）日：2015-01-21