1,3,5-Tri(ethenesulfonyl)benzene | 63226-60-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3,5-Tri(ethenesulfonyl)benzene
• 英文别名: 1,3,5-tris(ethenylsulfonyl)benzene
• CAS: 63226-60-8
• 化学式: C₁₂H₁₂O₆S₃
• 分子量: 348.4
• InChiKey: VMWMDCNYXKAFDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  128
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• BICYCLIC PEPTIDE LIGANDS AND USES THEREOF
  申请人：BicycleTx Limited

  公开号：US20180311300A1

  公开（公告）日：2018-11-01

  The present invention provides compounds, compositions thereof, and methods of using the same.

  本发明提供了化合物、其组合物以及使用它们的方法。
• Bicyclic peptide ligands and uses thereof
  申请人：BicycleTx Limited

  公开号：US10857196B2

  公开（公告）日：2020-12-08

  The present invention provides compounds, compositions thereof, and methods of using the same.

  本发明提供了化合物、其组合物以及使用方法。
• US4088495A
  申请人：——

  公开号：US4088495A

  公开（公告）日：1978-05-09
• [EN] ANTI-INFECTIVE BICYCLIC PEPTIDE CONJUGATES<br/>[FR] CONJUGUÉS PEPTIDIQUES BICYCLIQUES ANTI-INFECTIEUX
  申请人：BICYCLETX LTD

  公开号：WO2021220011A1

  公开（公告）日：2021-11-04

  The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the bicyclic peptides of the invention are conjugated to a carrier peptide in order to greatly enhance the bacterial cell killing activity. More particularly, the invention describes peptides which are high affinity binders of Lipid II. The invention also includes pharmaceutical compositions comprising said conjugates and to the use of said conjugates in suppressing or treating a disease or disorder mediated by bacterial infection or for providing prophylaxis to a subject at risk of infection.