Diphenylmethyl diisothiocyanate | 113260-82-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Diphenylmethyl diisothiocyanate
• 英文别名: [Diisothiocyanato(phenyl)methyl]benzene
• CAS: 113260-82-5
• 化学式: C₁₅H₁₀N₂S₂
• 分子量: 282.39
• InChiKey: QROGZRBOTBXEPS-UHFFFAOYSA-N

物化性质

• 沸点：
  379.8±30.0 °C(Predicted)
• 密度：
  1.13±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  88.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二氯二苯甲烷 以96%的产率得到
  参考文献：
  名称：

  HAMED, ATEF;MULLER, EDGAR;AL-TALIB, MAHMOUD;JOCHIMS, JOHANNES C., SYNTHESIS,(1987) N 8, 745-748

  摘要：

  DOI：

文献信息

• On the Reactions of<i>a</i>-Chlorocarbenium Ions with Ammonium Thiocyanate and Potassium Cyanate
  作者：Atef Hamed、Edgar Müller、Mahmoud Al-Talib、Johannes C. Jochims

  DOI：10.1055/s-1987-28073

  日期：——

  Preparations of 1-thia-3-azabutatrienium salts 2 from ammonium thiocyanate and α-chlorocarbenium salts 3 of the Vilsmeier-Arnold type, and of the geminal diisothiocyanates 6 are described, α-Chlorocarbenium salts react with potassium cyanate and ketones or tertiary carboxamides to give 2-azaallenium salts 9. A mechanistically interesting reaction of α-chlorocarbenium cations with carbonyl compounds has been observed.

  介绍了由硫氰酸铵和 Vilsmeier-Arnold 型δ-氯羰基盐 3 制备 1-硫杂-3-氮杂丁三烯酸盐 2 以及宝石二异硫氰酸盐 6 的制备方法，δ-氯羰基盐与氰酸钾和酮或叔羧酰胺反应生成 2-氮杂烯酸盐 9。还观察到δ-氯羰阳离子与羰基化合物发生了有趣的机械反应。
• Amine terminated block copolymers and processes for their preparation
  申请人：THE FIRESTONE TIRE & RUBBER COMPANY

  公开号：EP0002196A1

  公开（公告）日：1979-06-13

  Polymers of anionically polymerized monomers such as mono-olefins, conjugated dienes, vinyl substituted aromatics, vinyl substituted pyridine, vinyl substituted quinolines, various aldehydes, various epoxides. various oxetanes, various oxygen-containing compounds, and the like are produced and end capped witb a polyisocyanate. or polyisothiocyanate having the formula R(N=C=X)n wherein R is a hydrocarbon, n is 2 or 3, and X is oxygen or sulfur. Such end capped polymers, of course, contain one reacted or connected isocyanate or isothiocyanate group and at least one free isocyanate or isothiocyanate end group, which free end group(s) reacts with an amide to give an imide end group. The imide terminated polymer is then hydrolyzed to form a stable amine terminated polymer. The reaction of the amide compound with the isocyanate(s) or isothiocyanate(s), followed by hydrolysis, results in the replacement of the free isocyanate or isothiocyanate end group(s) with an amine group(s). Thus, the amine terminated polymer contains the polymer connected to an isocyanate or isothiocyanate group (now an amide group or a thioamide group), which in turn is attached to the hydrocarbon portion, that is, the "R" portion of the polyisocyanate, which in turn is connected to the formed amine group. The amine terminated polymers may be stored extended periods of time and then reacted with various polymers, prepolymers, monomers, or various combinations thereof to form various block or graft copolymers. That is, the amine terminated polymer may be subsequently reacted with any amine reactive compound such as diepoxy monomers or an epoxy prepolymer in the presence of known epoxy catalysts to give a blocked epoxy copolymer. Similarly, the amine terminated polymer may be reacted with urea prepolymers or urea-forming monomers to yield a block urea copolymer. Reaction of the amine terminated polymer with urethane polymers, urethane prepolymers, or urethane-forming monomers will yield a urethane block copolymer. Reaction of the amine terminated polymer with urethane-urea prepolymers or urethane-urea forming monomers will yield a urethane-urea block copolymer. Similarly, various dianhydride and diamine monomers may be utilized to form an imide block copolymer.

  生产阴离子聚合单体（如单烯烃、共轭二烯、乙烯基取代的芳烃、乙烯基取代的吡啶、乙烯基取代的喹啉、各种醛、各种环氧化物、各种氧杂环丁烷、各种含氧化合物等）的聚合物，并用具有式 R(N=C=X)n 的多异氰酸酯或多异硫氰酸酯封端，其中 R 是烃，n 是 2 或 3，X 是氧或硫。当然，这种末端封端的聚合物包含一个已反应或连接的异氰酸酯或异硫氰酸酯基团和至少一个游离的异氰酸酯或异硫氰酸酯末端基团，游离的末端基团与酰胺反应生成亚胺末端基团。然后，酰亚胺端基聚合物水解形成稳定的胺端基聚合物。酰胺化合物与异氰酸酯或异硫氰酸盐反应后水解，游离的异氰酸酯或异硫氰酸盐端基会被胺基团取代。因此，胺封端聚合物含有与异氰酸酯或异硫氰酸酯基团（现为酰胺基团或硫代酰胺基团）相连的聚合物，而异氰酸酯或异硫氰酸酯基团又与多异氰酸酯的烃部分，即 "R "部分相连，而 "R "部分又与形成的胺基团相连。胺封端聚合物可长期储存，然后与各种聚合物、预聚物、单体或其各种组合反应，形成各种嵌段或接枝共聚物。也就是说，胺封端聚合物随后可以在已知环氧催化剂的存在下，与任何胺活性化合物（如二环氧单体或环氧预聚物）反应，生成嵌段环氧共聚物。同样，胺封端聚合物也可与脲预聚物或脲形成单体反应，生成嵌段脲共聚物。胺封端聚合物与氨基甲酸乙酯聚合物、氨基甲酸乙酯预聚物或氨基甲酸乙酯形成单体反应，可生成氨基甲酸乙酯嵌段共聚物。胺封端聚合物与氨基甲酸乙酯-尿素预聚物或氨基甲酸乙酯-尿素形成单体反应将产生氨基甲酸乙酯-尿素嵌段共聚物。同样，各种二酐和二胺单体也可用于形成酰亚胺嵌段共聚物。
• Albumin-fixed resin, process for its production, method of using it to remove noxious substances from solutions containing them, and its use in removing noxious substances from blood
  申请人：TEIJIN LIMITED

  公开号：EP0028937A2

  公开（公告）日：1981-05-20

  The invention provides an albumin-fixed resin comprising a crosslinked water-insoluble resin and albumin chemically bound thereto, said water-insoluble resin being a crosslinked epoxy resin containing 1 to 30 milliequivalents of amino groups and 1 to 50 milliequivalents of hydroxyl groups per gram thereof, said albumin being bound ionically to the amino groups and by hydrogen bonding to the hydroxyl groups, and the amount of said albumin fixed being at least 25% by weight based on the epoxy resin. Also provided is a process for producing the albumin-fixed resin, which process comprises (1) (a) subjecting a polyepoxy compound containing at least two epoxy groups in the molecule, and a polyamine compound containing at least two primary and/or secondary amino groups in the molecule to addition reaction in an inert medium to produce a fully crosslinked resin, or (b) subjecting said polyepoxy and polyamine compounds to addition reaction to produce an incompletely crosslinked pre-polymer, and then reacting the pre-polymer with at least one organic polyisocyanate, organic polyisothiocyanate or organic polycarboxylic acid halide to crosslink the pre-polymer fully, and (2) contacting the resulting crosslinked epoxy resin containing 1 to 30 milliequivalents of amino groups and 1 to 50 milliequivalents of hydroxyl groups per gram thereof intimately with an aqueous solution containing albymin, optionally after partially neutralizing the amino groups of the epoxy resin. The albumin-fixed resin is useful for removing noxious substances capable of binding to albumin, such as bilirubin, from the blood of a warm-blooded animal.

  本发明提供了一种白蛋白固定树脂，包括交联的水不溶性树脂和与之化学结合的白蛋白，所述水不溶性树脂是一种交联环氧树脂，每克含有 1 至 30 毫当量的氨基和 1 至 50 毫当量的羟基，所述白蛋白通过离子键与氨基结合，并通过氢键与羟基结合，所述固定白蛋白的量至少为环氧树脂重量的 25%。 还提供了一种生产白蛋白固定树脂的工艺，该工艺包括 (1) (a) 将分子中含有至少两个环氧基团的聚环氧化合物和分子中含有至少两个伯氨基 和/或仲氨基的聚胺化合物在惰性介质中进行加成反应，生成全交联树脂、或 (b) 使所述聚环氧化合物和聚胺化合物进行加成反应，生成不完全交联的预聚 物，然后使该预聚物与至少一种有机多异氰酸酯、有机多异硫氰酸酯或有 机多羧酸卤化物反应，使该预聚物完全交联，以及 (2) 将得到的每克含有 1 至 30 毫当量氨基和 1 至 50 毫当量羟基的交联环氧树脂 与含有白胺的水溶液紧密接触，可选择在部分中和环氧树脂的氨基之后进 行。 白蛋白固定树脂可用于去除温血动物血液中能与白蛋白结合的有害物质，如胆红素。
• Application of ambient temperature cured polymers of prepolymers to a cured elastomer
  申请人：THE FIRESTONE TIRE & RUBBER COMPANY

  公开号：EP0123070A2

  公开（公告）日：1984-10-31

  A process and composition for applying and bonding an amine curable polymer or prepolymer at ambient temperatures to the surface of a cured elastomer substrate. The elastomer article or substrate is treated with an organic oxidant such as an N-halohydantoin, N-haloamide, or an N-haioimide, for example, the various isomers of mono-, di-, and trichloroisocyanuric acid. A polyisocyanate is applied thereto. A composition of the amine curable polymer or prepolymer is prepared with an amine curing agent. To the curing agent and curable polymer or prepolymer composition is added a polar solvent which is mixed with the resulting blend or mixture and added to the treated elastomer surface; said polymer or prepolymer cures at ambient temperature and becomes bonded to said elastomer. The application is relatively easy, since the entire mixture is a liquid and can be applied in situ. The invention is particularly suitable for repairing various damaged elastomer articles such as tires (especially off-the-road), conveyor belts, hoses, preparation of caulking or sealing compounds, and especially in bonding tire lugs or tire treads to a tire carcass.

  一种在环境温度下将胺固化聚合物或预聚物涂抹和粘合到固化弹性体基材表面的工艺和组合物。用有机氧化剂，如 N-卤代海因、N-卤代酰胺或 N-卤代亚胺，例如一氯、二氯和三氯异氰尿酸的各种异构体，处理弹性体制品或基材。多异氰酸酯用于其中。用胺固化剂制备胺固化聚合物或预聚物的组合物。在固化剂和可固化聚合物或预聚物组合物中加入极性溶剂，将其与所得混合物或混合料混合并加入处理过的弹性体表面；所述聚合物或预聚物在环境温度下固化并与所述弹性体粘合。由于整个混合物都是液体，可以就地使用，因此使用起来相对容易。本发明特别适用于修复各种受损的弹性体，如轮胎（尤其是越野轮胎）、传送带、软管，制备填缝剂或密封化合物，尤其适用于将胎耳或胎面粘合到轮胎胎体上。
• Amine curable prepolymer or polymer precured elastomer tread application at ambient or relatively low temperatures
  申请人：THE FIRESTONE TIRE & RUBBER COMPANY

  公开号：EP0316666A1

  公开（公告）日：1989-05-24

  A composition and process for applying and adhering a cured elastomer tread to a cured elastomer article such as a tire at an ambient or a relatively low temperature. The tire is buffed, ground, and otherwise reduced to a suitable depth for the application of the tread thereto. An adhesive system includes a treating agent such as a N-halohydantoin, a N-haloamide, and N-­haloimide, or a N-halosulfonamide, which is applied to the prepared tire surface. The adhesive system also includes an amine curable polymer or prepolymer contain­ing an amine curing agent therein and an optional polar solvent is applied to the treated tire surface and to the elastomeric tire tread. The tire tread is then applied to the prepared tire and cured at a relatively low or ambient temperatures. Various additives can be added to the amine curable polymer or prepolymer and/or treating agent or to the tire and tread surface to im­prove adhesion of the tread to the tire carcass. The invention is suitable for passenger vehicle type tires, off-the-road type tires, and the like.

  一种在环境温度或相对较低的温度下将固化弹性体胎面涂覆和粘附到固化弹性体制品（如轮胎）上的组合物和工艺。将轮胎磨光、磨碎或以其他方式减薄至适当深度，以便在其上涂抹胎面。粘合剂系统包括一种处理剂，如 N-卤代海因、N-卤代酰胺、N-卤代亚胺或 N-卤代磺酰胺，将其涂在制备好的轮胎表面。粘合剂系统还包括胺固化聚合物或其中含有胺固化剂的预聚物，并将任选的极性溶剂涂抹在处理过的轮胎表面和弹性轮胎胎面上。然后将轮胎胎面涂抹到准备好的轮胎上，并在相对较低的温度或环境温度下固化。胺固化聚合物或预聚物和/或处理剂或轮胎和胎面可添加各种添加剂，以提高胎面与轮胎胎体的附着力。本发明适用于乘用车轮胎、越野车轮胎等。