4-methyl-4-phenyl-hex-1-ene | 171505-06-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-4-phenyl-hex-1-ene
• 英文别名: 4-Methyl-4-phenyl-hex-1-en；(3-Methylhex-5-en-3-yl)benzene；3-methylhex-5-en-3-ylbenzene
• CAS: 171505-06-9
• 化学式: C₁₃H₁₈
• 分子量: 174.286
• InChiKey: PRYACGDVDNQDEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-苯基-2-丁醇 、 烯丙基三甲基硅烷 在 亚氨基二硫酰氟 作用下， 以 二氯甲烷 为溶剂， 反应 0.17h， 以78%的产率得到4-methyl-4-phenyl-hex-1-ene
  参考文献：
  名称：

  Bis(fluorosulfuryl)imide: a Brönsted Acid Catalyst for the Coupling of Allylic and Benzylic Alcohols With Allyltrimethylsilane

  摘要：

  The Bronsted acid HN(SO2F)(2) catalyses the reaction of allylic and benzylic alcohols with allyltrimethylsilane to give the corresponding coupled products in good yields. (C) 1997 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)00390-0

文献信息

• Vanadium(II) complexes as efficient reagents for direct construction of asymmetric quaternary carbons from carbonyl compounds
  作者：Yasutaka Kataoka、Isamu Makihira、Hiroaki Akiyama、Kazuhide Tani

  DOI：10.1016/0040-4039(95)01299-w

  日期：1995.9

  Direct geminal diallylation of propiophenone with allyl bromide has been achieved in the presence of vanadium(II) species. By applying this method, direct construction of asymmetric quaternary carbons from propiophenone has been accomplished. Strong oxophilicity of the low-valent vanadium facilitated the deoxygenative reaction. The present reaction is characteristic of vanadium complexes.

  在钒（II）物种存在下，苯丙酮与烯丙基溴直接进行双键二烯丙基化反应。通过应用该方法，已经实现了由苯乙酮直接构建不对称季碳的方法。低价钒的强亲氧性促进了脱氧反应。本反应是钒配合物的特征。
• Direct construction of quaternary carbons from carbonyl compounds utilizing low-valent vanadium complexes
  作者：Yasutaka Kataoka、Isamu Makihira、Hiroaki Akiyama、Kazuhide Tani

  DOI：10.1016/s0040-4020(97)00632-7

  日期：1997.7

  Direct geminal diallylation of a carbonyl compound with allyl bromide has been achieved in the presence of a low-valent vanadium complex and zinc. The diallylation has been found to proceed stepwise and the two allyl groups were introduced successively. By applying this method, one-pot synthesis of asymmetric quaternary carbons has been accomplished. As the first alkylating reagent a combination of allyl bromide and zinc, a Grignard reagent, or an alkyllithium can be used. The second one should be the combination of a low-valent vanadium(II) complex and allyl bromide, benzyl bromide, or propargyl bromide. Strong oxophilicity of the low-valent vanadium facilitated the deoxygenative allylation. (C) 1997 Elsevier Science Ltd.
• Colonge; Garnier, Bulletin de la Societe Chimique de France, 1948, p. 436,438
  作者：Colonge、Garnier

  DOI：——

  日期：——
• Bis(fluorosulfuryl)imide: a Brönsted Acid Catalyst for the Coupling of Allylic and Benzylic Alcohols With Allyltrimethylsilane
  作者：Gurmeet Kaur、Monica Kaushik、Sanjay Trehan*

  DOI：10.1016/s0040-4039(97)00390-0

  日期：1997.4

  The Bronsted acid HN(SO2F)(2) catalyses the reaction of allylic and benzylic alcohols with allyltrimethylsilane to give the corresponding coupled products in good yields. (C) 1997 Published by Elsevier Science Ltd.