(R)-1-[1,3]Dioxolan-2-yl-2-methyl-propan-1-ol | 126064-68-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 英文名称: (R)-1-[1,3]Dioxolan-2-yl-2-methyl-propan-1-ol
• 英文别名: (1R)-1-(1,3-dioxolan-2-yl)-2-methylpropan-1-ol
• CAS: 126064-68-4
• 化学式: C₇H₁₄O₃
• 分子量: 146.186
• InChiKey: BEZMKTCCKRAWDA-ZCFIWIBFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 (R)-1-[1,3]Dioxolan-2-yl-2-methyl-propan-1-ol
  参考文献：
  名称：

  Application of the iron acyl complex R-(-)-[(η5-C5H5)Fe(CO)(PPh3)- COCH2O(\{{1R,2S\}},5Rmenthyl)] as a homochiral formyl anion equivalent

  摘要：

  DOI：

  10.1016/s0040-4039(00)99172-x

文献信息

• Kinetic Resolution of Racemic 2-Hydroxyacetals by Asymmetric Esterification Using a Mixed Anhydride Protocol
  作者：Isamu Shiina、Kenya Nakata、Eri Tokumaru、Takahiro Saitoh、Keisuke Ono、Takayoshi Nakahara、Takatsugu Murata

  DOI：10.3987/com-16-s(s)17

  日期：——

  The non-enzymatic kinetic resolution of racemic 2-hydroxyacetals via asymmetric esterification with diphenylacetic acid and pivalic anhydride catalyzed by the chiral acyl transfer catalyst (R)-BTM is reported. The reaction transition states were elucidated using theoretical calculations; it was found that 1,3-dioxolane is a suitable reagent for attaining high selectivity.