Lauroimidoaethylester | 80538-42-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 甲亚胺酸及其衍生物
• 英文名称: Lauroimidoaethylester
• 英文别名: Ethyldodecaneimidate；ethyl dodecanimidate
• CAS: 80538-42-7
• 化学式: C₁₄H₂₉NO
• 分子量: 227.39
• InChiKey: RVESDUIOFUGWJK-UHFFFAOYSA-N

物化性质

• 沸点：
  284.3±23.0 °C(Predicted)
• 密度：
  0.87±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  16
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Lauroimidoaethylester 在 盐酸 作用下， 以 水 为溶剂， 反应 4.0h， 生成 月桂酸乙酯
  参考文献：
  名称：

  The Conversion of Amides to Esters with Meerwein'S Reagent. Application to the Synthesis of a Carfentanil Precursor.

  摘要：

  An efficient two step transformation of 1 degrees and 2 degrees amides to methyl and ethyl esters has been developed using trimethyl- and triethyloxonium tetrafluoroborates, and dilute acid. This methodology was applied to 1-benzyl-4-phenylamino-4-piperidinecarboxamide precursor in the synthesis of carfentanil, to produce the methyl ester in 60% yield and the ethyl ester in 80% yield.

  DOI：

  10.1080/00397919708004212
• 作为产物：
  描述：

  乙醇 、 十二腈 在 盐酸 作用下， 生成 Lauroimidoaethylester
  参考文献：
  名称：

  George,E.E.; Polya,J.B., Australian Journal of Chemistry, 1979, vol. 32, p. 2701 - 2712

  摘要：

  DOI：

文献信息

• Process for initiating radical reactions employing hydroximic acid
  申请人：Akzona Incorporated

  公开号：US04347342A1

  公开（公告）日：1982-08-31

  This disclosure relates to an improved process for initiating radical reactions employing a class of hydroximic acid derivatives as initiators. Radical reactions initiated by such hydroximic acid derivatives include copolymerization of unsaturated polyester resins and cross-linking of polyethylene. The initiators of the present disclosure have a higher degradation temperature than found with typical peroxides.

  本公开涉及一种通过使用一类羟肟酸衍生物作为引发剂来启动自由基反应的改进工艺。由这类羟肟酸衍生物引发的自由基反应包括不饱和聚酯树脂的共聚反应和聚乙烯的交联反应。本公开的引发剂比通常的过氧化物具有更高的降解温度。
• Process for carrying out radical reactions and shaped articles of the reaction product
  申请人：AKZO N.V.

  公开号：EP0035291B1

  公开（公告）日：1983-05-11
• George,E.E.; Polya,J.B., Australian Journal of Chemistry, 1979, vol. 32, p. 2701 - 2712
  作者：George,E.E.、Polya,J.B.

  DOI：——

  日期：——
• The Conversion of Amides to Esters with Meerwein'S Reagent. Application to the Synthesis of a Carfentanil Precursor.
  作者：Anthony J. Kiessling、Cynthia K. McClure

  DOI：10.1080/00397919708004212

  日期：1997.3

  An efficient two step transformation of 1 degrees and 2 degrees amides to methyl and ethyl esters has been developed using trimethyl- and triethyloxonium tetrafluoroborates, and dilute acid. This methodology was applied to 1-benzyl-4-phenylamino-4-piperidinecarboxamide precursor in the synthesis of carfentanil, to produce the methyl ester in 60% yield and the ethyl ester in 80% yield.