O,O-dimethyl-2,6-pyridinyldi(formyloxy-4-methoxybenzylphosphonate) | 1207757-83-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: O,O-dimethyl-2,6-pyridinyldi(formyloxy-4-methoxybenzylphosphonate)
• 英文别名: Bis[dimethoxyphosphoryl-(4-methoxyphenyl)methyl] pyridine-2,6-dicarboxylate
• CAS: 1207757-83-2
• 化学式: C₂₇H₃₁NO₁₂P₂
• 分子量: 623.49
• InChiKey: JQJOHQIXWVAWEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  42
• 可旋转键数：
  16
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  155
• 氢给体数：
  0
• 氢受体数：
  13

反应信息

• 作为产物：
  描述：

  2,6-氯甲酰吡啶 、 [hydroxy-(4-methoxy-phenyl)-methyl]-phosphonic acid dimethyl ester 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 5.0h， 以46%的产率得到O,O-dimethyl-2,6-pyridinyldi(formyloxy-4-methoxybenzylphosphonate)
  参考文献：
  名称：

  Synthesis and Biological Activity of O,O-Dimethyl-2,6-Pyridinyl Diformyloxy Alkyl Phosphonates

  摘要：

  In an attempt to discover novel compounds with high activity and low toxicity, a series of new O,O-dimethyl-2,6-pyridinyl diformyloxy alkyl phosphonates 4a-4p has been designed and synthesized by the reaction of 2,6-pyridinyl diformyloxy chloride with alpha-hydroxyalkyl phosphonate. The structures of all new compounds were characterized by elementary analysis, IR, (1)H NMR, and MS spectroscopies. The results of a preliminary bioassay indicate that some of the target compounds have obviously promotive action for plant growth against the stalk of barnyard grass.

  DOI：

  10.1080/10426500802583553

文献信息

• Synthesis and Biological Activity of <i>O,O</i>-Dimethyl-2,6-Pyridinyl Diformyloxy Alkyl Phosphonates
  作者：Tao Wang、Da You Lei、Ying Huang、Li Hua Ao

  DOI：10.1080/10426500802583553

  日期：2009.10.30

  In an attempt to discover novel compounds with high activity and low toxicity, a series of new O,O-dimethyl-2,6-pyridinyl diformyloxy alkyl phosphonates 4a-4p has been designed and synthesized by the reaction of 2,6-pyridinyl diformyloxy chloride with alpha-hydroxyalkyl phosphonate. The structures of all new compounds were characterized by elementary analysis, IR, (1)H NMR, and MS spectroscopies. The results of a preliminary bioassay indicate that some of the target compounds have obviously promotive action for plant growth against the stalk of barnyard grass.