(4-tert-butyl-phenyl)-isobutyl ether | 876477-01-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-tert-butyl-phenyl)-isobutyl ether
• 英文别名: (4-tert-Butyl-phenyl)-isobutyl-aether；4-Isobutyloxy-1-tert.-butyl-benzol；<4-tert.-Butyl-phenyl>-isobutylaether；1-Isobutoxy-4-tert.-butyl-benzol；1-Tert-butyl-4-(2-methylpropoxy)benzene
• CAS: 876477-01-9
• 化学式: C₁₄H₂₂O
• mdl: MFCD20538964
• 分子量: 206.328
• InChiKey: ITZFTBJQPRSOPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.571
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  碘代异丁烷 、 alkaline earth salt of/the/ methylsulfuric acid 在 水 作用下， 生成 (4-tert-butyl-phenyl)-isobutyl ether
  参考文献：
  名称：

  Dains; Rothrock, American Chemical Journal, 1894, vol. 16, p. 635

  摘要：

  DOI：

文献信息

• SODIUM CHANNEL INHIBITORS
  申请人：Fulp Alan Bradley

  公开号：US20090023740A1

  公开（公告）日：2009-01-22

  Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.

  提供了在通过抑制电压门控钠通道中的钠离子通量来治疗疾病方面有用的化合物、组合物和方法。更具体地，本发明提供了取代磺胺基的化合物、包含这些化合物的组合物，以及使用这些化合物或组合物治疗中枢或外周神经系统疾病的方法，特别是通过阻断与所示疾病的发作或复发相关的钠通道来治疗疼痛和慢性疼痛。本发明的化合物、组合物和方法特别适用于通过抑制电压门控钠通道中的离子通量来治疗神经病理性或炎症性疼痛。
• NITROGENOUS COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME
  申请人：LG CHEM, LTD.

  公开号：US20200331932A1

  公开（公告）日：2020-10-22

  The present specification relates to a compound containing nitrogen, and a color conversion film, a backlight unit, and a display device, including the same.

  本规范涉及一种含氮化合物，以及包括该化合物的颜色转换膜、背光单元和显示装置。
• CYSTEINE PROTEASE INHIBITORS
  申请人：Unoki Gen

  公开号：US20090291945A1

  公开（公告）日：2009-11-26

  To provide a compound having an excellent cysteine protease inhibitory effect, and to provide a drug for treatment or prevention of the disease selected from the group consisting of osteoporosis, osteoarthritis, chronic rheumatoid arthritis, Paget's disease of bone, hypercalcemia, bone metastasis of cancer, and ostealgia. A compound represented by formula (1) or a pharmaceutically acceptable salt thereof, or a drug or pharmaceutical composition containing the same as an effective component.

  提供一种具有优异半胱氨酸蛋白酶抑制作用的化合物，并提供一种用于治疗或预防骨质疏松症、骨关节炎、慢性类风湿性关节炎、骨Paget病、高钙血症、骨癌转移和骨痛的药物。化合物由式（1）表示，或其药学上可接受的盐，或将其作为有效成分的药物或药物组合物。
• TONER FOR ELECTROPHOTOGRAPHY AND METAL-CONTAINING COMPOUND
  申请人：Ookubo Kimihiko

  公开号：US20120116110A1

  公开（公告）日：2012-05-10

  Disclosed is a toner for electrophotography, which has good hue, good light resistance and good electrostatic charge, and is capable of providing images that are free from white spots. The toner for electrophotography exhibits a good performance. Specifically disclosed is a toner for electrophotography, which is characterized by containing at least one metal-containing compound that is represented by general formula (1). (In the formula, R1 represents an alkyl group; R2 represents a hydrogen atom, an alkoxycarbonyl group, an aryloxycarbonyl group, a sulfamoyl group, a sulfinyl group, an alkylsulfonyl group, an arylsulfonyl group, an acyl group, a halogen atom or a cyano group; and R3 represents a group that has 9 or more carbon atoms and an aromatic hydrocarbon structure.)

  公开了一种用于电子照相的色调良好，耐光性好，静电荷能力强且能提供没有白斑的图像的色调剂。该电子照相色调剂表现出良好的性能。具体公开了一种用于电子照相的色调剂，其特征在于至少含有一个由通式（1）表示的含金属化合物。（在该式中，R1代表烷基；R2代表氢原子，烷氧羰基，芳基氧羰基，磺酰基，亚磺基，烷基磺酰基，芳基磺酰基，酰基，卤素原子或氰基；R3代表具有9个或更多碳原子和芳香族碳氢结构的基团。）
• Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
  申请人：CV6 Therapeutics (NI) Limited

  公开号：US10544105B2

  公开（公告）日：2020-01-28

  Provided herein are dUTPase inhibitors of Formula (I), compositions comprising such compounds and methods of using such compounds and compositions

  本文提供了式 (I) 的 dUTP 酶抑制剂、包含此类化合物的组合物以及使用此类化合物和组合物的方法