3-(2-hydroxy-ethyl)-2-methyl-benzothiazolium | 58982-01-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 3-(2-hydroxy-ethyl)-2-methyl-benzothiazolium
• 英文别名: 2-Methyl-3-(2-hydroxyethyl)-benzothiazolium；2-Methyl-3-(2-hydroxyethyl)-benzthiazolium；3-(2-Hydroxyethyl)-2-methyl-1,3-benzothiazol-3-ium；2-(2-methyl-1,3-benzothiazol-3-ium-3-yl)ethanol
• CAS: 58982-01-7
• 化学式: C₁₀H₁₂NOS
• mdl: MFCD00600556
• 分子量: 194.277
• InChiKey: DUPDJONYRNIZRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  52.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-(2-hydroxy-ethyl)-2-methyl-benzothiazolium 、 2H-1-苯并吡喃-3-羧醛, 7-(二乙基氨基)-2-氧代- 在 哌啶 作用下， 以 甲醇 为溶剂， 生成 7-(Diethylamino)-3-[2-[3-(2-hydroxyethyl)-1,3-benzothiazol-3-ium-2-yl]ethenyl]chromen-2-one
  参考文献：
  名称：

  [EN] LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES
  [FR] FLUOROPHORES REAGISSANT A THIOL A LONGUEURS D'ONDES ELEVEES

  摘要：

  公开号：

  WO2006025887A3
• 作为产物：
  描述：

  2-甲基苯并噻唑 、 2-溴乙醇 反应 24.0h， 生成 3-(2-hydroxy-ethyl)-2-methyl-benzothiazolium
  参考文献：
  名称：

  [EN] LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES
  [FR] FLUOROPHORES REAGISSANT A THIOL A LONGUEURS D'ONDES ELEVEES

  摘要：

  公开号：

  WO2006025887A3

文献信息

• Dyes and methods of detection of nucleic acid in immature red blood cells
  申请人：——

  公开号：US20020037589A1

  公开（公告）日：2002-03-28

  The dyes of the present invention are useful for many purposes that include markers or tags for detecting the presence of a molecule or compound to which they are bound. The dyes may be either red-excitable or blue-excitable. The dyes of the invention are particularly well suited for staining of nucleic acids. For example, these dyes are particularly suitable for staining of RNA in reticulocytes. In another exemplary application, these dyes are suitable for staining DNA in nucleated red blood cells. Typically, when used in staining of nucleic acids, the dyes are formulated into reagent solutions. In addition, the invention provides compositions and methods for facilitating rapid transport of dye molecules through a cell membrane. Such rapid staining requires that a sample be contacted with a dye composition of the invention in the presence of at least one surfactant and optionally, a sulfonic acid or a salt thereof.

  本发明的染料可用于许多目的，包括作为标记或标签，用于检测它们所结合的分子或化合物的存在。这些染料可以是红色激发的或蓝色激发的。本发明的染料特别适合用于染色核酸。例如，这些染料特别适合于染色网织红细胞中的RNA。在另一个示例应用中，这些染料适合于染色有核红细胞中的DNA。通常，在染色核酸时，这些染料被制成试剂溶液。此外，本发明提供了促进染料分子快速穿过细胞膜的组合物和方法。这种快速染色需要将样品与本发明的染料组合物接触，并在至少一种表面活性剂和可选的磺酸或其盐的存在下进行。
• Zwitterionic Non-Linear Optophores And Devices Incorporating Same
  申请人：Kay John Andrew

  公开号：US20070208182A1

  公开（公告）日：2007-09-06

  The invention relates to zwitterionic second order non-linear optophores comprising a compound of general Formula I: wherein D is selected from: and L and R1-R5 are as herein defined. Also, provided are polymeric compositions incorporating these compounds. These optophores display a large and efficient non-linear optical response and therefore can be used in the production of optoelectronic devices.

  本发明涉及带电离子的二次非线性光致移动分子，包括一般式I中的化合物，其中D选自：而L和R1-R5如本文所定义。同时，提供了包含这些化合物的聚合物组合物。这些光致移动分子表现出大而有效的非线性光学响应，因此可以用于光电子器件的生产。
• Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection
  申请人：National Health Research Institutes

  公开号：EP1627635B1

  公开（公告）日：2009-10-07
• COMPOSES DERIVES D'IRIDOIDES PROTEGES OU NON, COMPOSITION LES COMPRENANT, UTILISATION COMME COLORANT DES FIBRES KERATINIQUES ET DISPOSITIFS
  申请人：L'Oréal

  公开号：EP2978749A1

  公开（公告）日：2016-02-03
• LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES
  申请人：Pitner J. Bruce

  公开号：US20100003763A1

  公开（公告）日：2010-01-07

  Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus.