3,6-dibutyl-2-methylpyridine | 55277-89-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3,6-dibutyl-2-methylpyridine
• CAS: 55277-89-9
• 化学式: C₁₄H₂₃N
• 分子量: 205.343
• InChiKey: AVAIELGRGAFNOK-UHFFFAOYSA-N

物化性质

• 沸点：
  284.1±9.0 °C(Predicted)
• 密度：
  0.890±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-己炔 、 乙腈 以40%的产率得到
  参考文献：
  名称：

  WAKATSUKI Y.; YAMAZAKI H., SYNTHESIS , 1976, NO 1, 26-28

  摘要：

  DOI：

文献信息

• Open-Vessel Microwave-Mediated [2+2+2]-Cyclotrimerization Reactions
  作者：Alexander Deiters、Douglas Young、Jesse Teske

  DOI：10.1055/s-0029-1218149

  日期：2009.11

  [2+2+2]-Cyclotrimerization reactions often suffer from low reaction rates and low chemoselectivity. We are reporting a solution to both problems through the use of open-vessel conditions for microwave-mediated cyclotrimerization reactions. [2+2+2] cyclotrimerization - alkynes - microwave - bicyclic compounds - transition metal catalysis

  [2 + 2 + 2]-环三聚反应通常遭受低反应速率和低化学选择性的困扰。我们正在报告通过使用开放容器条件进行微波介导的环三聚反应来解决这两个问题。 [2 + 2 + 2]环三聚-炔烃-微波-双环化合物-过渡金属催化
• Cobalt atoms as catalysts of the synthesis of pyridines from nitriles and acetylenes
  作者：Giovanni Vitulli、Sergio Bertozzi、Raffaello Lazzaroni、Piero Salvadori

  DOI：10.1016/0022-328x(86)80486-7

  日期：1986.6

  Cobalt atoms have been found to provide efficient and selective catalysts for the synthesis of pyridines from nitriles and acetylenes; the reaction conditions are milder than those reported for other cobalt-containing catalysts.

  已发现钴原子可为从腈和乙炔合成吡啶提供有效和选择性的催化剂。该反应条件比其他含钴催化剂报道的条件温和。
• Nehl, Hans, Chemische Berichte, 1994, vol. 127, # 12, p. 2535 - 2538
  作者：Nehl, Hans

  DOI：——

  日期：——
• Electron transfer to excited doublet states. Photoirradiation of 10-methylphenothiazine cation radical perchlorate in solutions of phenylacetylene and p-tolylacetylene in acetonitrile
  作者：Henry J. Shine、Da Chuan Zhao

  DOI：10.1021/jo00300a026

  日期：1990.6
• Stoichiometric alkyne cyclotrimerization at a ruthenium centre: A new synthetic route to Ru(η6-arene)(η4-cycloocta-1,5-diene) complexes
  作者：Paolo Pertici、Alessandra Verrazzani、Giovanni Vitulli、Richard Baldwin、Martin A. Bennett

  DOI：10.1016/s0022-328x(97)00425-7

  日期：1998.1

  Alkynes RC2R' [R = H, R' = Bu-n, CH2CMeEt, (CH2)(5)C2H; R = R' = Me, Ph; R = Me, R' = Pr-n] undergo stoichiometric cyclotrimerization on reaction with the naphthalene-ruthenium(0) complex Ru(eta(6)-C10H8)(eta(4)-C8H12), 1, at room temperature to give the corresponding Ru(eta(6)-arene)(eta 4-C8H12) complexes in moderate to excellent yield. Unsymmetrical alkynes give a mixture of the isomeric eta(6)-1,3,5-(a) and eta(6)-1,2,4-arene (b) complexes, the ratio a:b being dependent on the electronic and steric effects of R and R'. In the presence of 1, 1-hexyne and 4-methyl-1-hexyne cocyclotrimerize with acetonitrile to give substituted pyridines, which are formed in addition to the Ru(eta(6)-arene)(eta(4)-C8H12) complexes. (C) 1998 Elsevier Science S.A.