N-[2-(2-hydroxyethoxy)ethyl]-3-nitro-1,8-naphthalimide | 651768-41-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-[2-(2-hydroxyethoxy)ethyl]-3-nitro-1,8-naphthalimide
• 英文别名: 2-[2-(2-Hydroxyethoxy)ethyl]-5-nitrobenzo[de]isoquinoline-1,3-dione
• CAS: 651768-41-1
• 化学式: C₁₆H₁₄N₂O₆
• 分子量: 330.297
• InChiKey: FZLCEGKCKKWIJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  113
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-[2-(2-hydroxyethoxy)ethyl]-3-nitro-1,8-naphthalimide 在 吡啶 、 palladium on activated charcoal 、 氢气 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成 N-[2-(2-acetoxyethoxy)ethyl]-3-amino-1,8-naphthalimide
  参考文献：
  名称：

  A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

  摘要：

  开发了一种新型双发射荧光探针，用于亚氯酸盐（ClO−）的特异性和灵敏检测。在加入ClO−后，观察到两个不同波长下荧光发射强度的显著变化。同时，氧化亚氮阴离子（OONO−）只引起单通道荧光增强。这一特性使其在区分ClO−与其他活性氧（ROS）方面具有明显优势。

  DOI：

  10.1039/c3cc38471c
• 作为产物：
  描述：

  3-硝基-1,8-萘二甲酸酐 、 二甘醇胺 以 乙醇 为溶剂， 反应 4.0h， 以68%的产率得到N-[2-(2-hydroxyethoxy)ethyl]-3-nitro-1,8-naphthalimide
  参考文献：
  名称：

  A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

  摘要：

  开发了一种新型双发射荧光探针，用于亚氯酸盐（ClO−）的特异性和灵敏检测。在加入ClO−后，观察到两个不同波长下荧光发射强度的显著变化。同时，氧化亚氮阴离子（OONO−）只引起单通道荧光增强。这一特性使其在区分ClO−与其他活性氧（ROS）方面具有明显优势。

  DOI：

  10.1039/c3cc38471c

文献信息

• Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition
  申请人：SAKAYORI Katsuya

  公开号：US20080275154A1

  公开（公告）日：2008-11-06

  The present invention provides a radical generator having a naphthalimide structure or a crosslinking agent and a photosensitive compound having a function as a radical generator. A photoradical polymerization initiator of the present invention comprises a compound (a) having only one naphthalimide structure-containing group in one molecule. The radial generator of the present invention comprises a compound (c) having two or more naphthalimide structure-containing groups in one molecule and also functions as a crosslinking agent. A first photosensitive compound of the present invention comprises a compound (d) having a naphthalimide structure-containing group and an ethylenic unsaturated group in one molecule. A second photosensitive compound of the present invention comprises a polymer (e) of one or more radical polymerizable compounds containing the compound (d). A photosensitive resin composition according to the present invention contains, as an essential component, the above compound (a), compound (c), compound (d) or polymer (e).
• US7410746B2
  申请人：——

  公开号：US7410746B2

  公开（公告）日：2008-08-12
• US8211613B2
  申请人：——

  公开号：US8211613B2

  公开（公告）日：2012-07-03
• A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells
  作者：Ting Guo、Lei Cui、Jiaoning Shen、Rui Wang、Weiping Zhu、Yufang Xu、Xuhong Qian

  DOI：10.1039/c3cc38471c

  日期：——

  A novel dual-emission fluorescence probe has been developed for specific and sensitive detection of hypochlorite (ClO−). Upon addition of ClO−, significant changes in fluorescence emission intensity at two discrete wavelengths were observed. Meanwhile OONO− led to only a single-channel fluorescence enhancement. This feature makes it a clear advantage in distinguishing ClO−, RNS from other ROS.

  开发了一种新型双发射荧光探针，用于亚氯酸盐（ClO−）的特异性和灵敏检测。在加入ClO−后，观察到两个不同波长下荧光发射强度的显著变化。同时，氧化亚氮阴离子（OONO−）只引起单通道荧光增强。这一特性使其在区分ClO−与其他活性氧（ROS）方面具有明显优势。