N-benzyl-N-propylaniline | 93026-56-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-benzyl-N-propylaniline
• 英文别名: N-Benzyl-N-propyl-anilin；Propylphenylbenzylamin；Propylbenzylanilin
• CAS: 93026-56-3
• 化学式: C₁₆H₁₉N
• 分子量: 225.334
• InChiKey: WJZNJZWXOFGUFC-UHFFFAOYSA-N

物化性质

• 沸点：
  145.5-146 °C(Press: 1.5 Torr)
• 密度：
  1.018±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 甲醇 、 magnesium 作用下， 生成 N-benzyl-N-propylaniline
  参考文献：
  名称：

  Singh, Journal of the Chemical Society, 1916, vol. 109, p. 790

  摘要：

  DOI：

文献信息

• Direct benzylation of amines with benzylic alcohols catalyzed by palladium/phosphine-borane catalyst system
  作者：Gen Onodera、Hidenobu Kumagae、Daiki Nakamura、Takuto Hayasaki、Tsutomu Fukuda、Masanari Kimura

  DOI：10.1016/j.tetlet.2020.152537

  日期：2020.11

  benzylation of amines with benzylic alcohols to give benzylamines has been newly developed by using palladium/phosphine-borane catalyst system. In this catalytic reaction, the linking between both phosphine and borane moieties in the ligand is very important. Hydroxy group of benzylic alcohols is activated by Lewis acidic borane to form a benzylpalladium intermediate which is attacked by amines to give benzylamine

  通过使用钯/膦-硼烷催化剂体系，新开发了胺与苄醇直接催化苄基化制得苄胺的方法。在该催化反应中，配体中的膦和硼烷部分之间的连接非常重要。苄醇的羟基被路易斯酸性硼烷活化，形成苄基钯中间体，该中间体被胺攻击，得到苄胺产物。
• METHOD FOR PRODUCING GLUCOSE BY ENZYMATIC HYDROLYSIS OF CELLULOSE THAT IS OBTAINED FROM MATERIAL CONTAINING LIGNO-CELLULOSE USING AN IONIC LIQUID THAT COMPRISES A POLYATOMIC ANION
  申请人：Balensiefer Tim

  公开号：US20100081798A1

  公开（公告）日：2010-04-01

  The present invention relates to a process for preparing glucose from a lignocellulose-comprising starting material, in which this is firstly treated with an ionic liquid and subsequently subjected to an enzymatic hydrolysis. The invention further relates to a process for preparing microbial metabolites, especially ethanol, in which the glucose obtained is additionally subjected to a fermentation.

  本发明涉及一种从含木质纤维素的起始物质制备葡萄糖的过程，首先将其与离子液体处理，然后经酶解处理。该发明还涉及一种制备微生物代谢产物，特别是乙醇的过程，其中所获得的葡萄糖额外经过发酵处理。
• [DE] DESTILLATION VON IONISCHEN FLÜSSIGKEITEN<br/>[EN] DISTILLATION OF IONIC LIQUIDS<br/>[FR] DISTILLATION DE LIQUIDES IONIQUES
  申请人：BASF AG

  公开号：WO2005068404A1

  公开（公告）日：2005-07-28

  Die Erfindung bezieht sich auf ein Verfahren zur Destillation ionischer Flüssigkeiten, bei welchem in einem Schritt en Druck unterhalb des Umgebungsdruckes eingestellt wird und in einem weitren Schritt die ionische Flüssigkeit auf eine Temperatur im Bereich von 60°C bis 350°C erwärmt wird. Das Verfahren dient insbesondere zur Reinigung ionischer Flüssigkeiten.

  该发明涉及一种离子液体蒸馏方法，其中在一步中将压力调节到低于环境压力，并在另一步中将离子液体加热至60°C至350°C范围内的温度。该方法主要用于清洁离子液体。
• PROCESS FOR PREPARING SILOXY CARBOXYLATES
  申请人：Gärtner Martin

  公开号：US20120157701A1

  公开（公告）日：2012-06-21

  A process for preparing siloxy carboxylates is characterized by reaction of C 2 -C 10 -monocarboxylic acids with halosiloxanes of the general formula (I), Hal-(SiR 2 —O) x —SiR 3 (I) in which Hal is the same or different and is fluorine, chlorine, bromine or iodine, R is hydrogen, C 1 -C 10 -alkyl or C 6 -C 14 -aryl and x is an integer from 1 to 20, to form hydrogen halide in the presence of an auxiliary base, in which the auxiliary base forms, with the hydrogen halide, a salt which forms two immiscible phases with the siloxy carboxylate or the solution of the siloxy carboxylate in a suitable solvent and is removed by a liquid-liquid separation. The process enables simple and economically viable preparation of siloxy carboxylates.

  一种制备硅氧羧酸酯的方法，其特征在于将C2-C10-单羧酸与一般式(I)的卤代硅氧烷发生反应，其中Hal-(SiR2—O)x—SiR3(I)，其中Hal是相同或不同的氟、氯、溴或碘，R是氢、C1-C10-烷基或C6-C14-芳基，x为1至20的整数，以形成氢卤素在辅助碱的存在下，其中辅助碱与氢卤素形成盐，与硅氧羧酸酯或硅氧羧酸酯在适当溶剂中的溶液形成两个不相溶的相，并通过液-液分离去除。该方法实现了硅氧羧酸酯的简单和经济可行的制备。
• Method of Separating Acids from Chemical Reaction Mixtures by Means of Apolar Amines
  申请人：Huttenloch Oliver

  公开号：US20080287709A1

  公开（公告）日：2008-11-20

  A process for the removal of acids from reaction mixtures, comprising at least one product of value which is sparingly soluble in water, by at least one unpolar amine as an auxiliary base, which includes: a) reacting the auxiliary base with the acid with formation of a salt; b) reacting the salt formed in step a) with a further base which accepts the acid with liberation of the auxiliary base and combines with the acid to be accepted from the auxiliary base to form a salt which is very readily soluble in water; c) extraction of the mixture obtained in step b) with water or an aqueous medium, wherein the salt of the further base dissolves in the aqueous phase and the product of value, or the solution of the product of value, in a suitable solvent and the auxiliary base form at least one separate nonaqueous phase; and d) removal by distillation of at least part of any solvent present from the at least one nonaqueous phase obtained in step c), to form two nonmiscible liquid phases.

  一种从反应混合物中去除酸的方法，包括至少一种在水中溶解度较低的具有价值的产物，通过至少一种非极性胺作为辅助碱，其步骤包括：a)将辅助碱与酸反应，形成盐；b)将步骤a)中形成的盐与另一接受酸的碱反应，释放出辅助碱并与从辅助碱中接受的酸结合，形成在水中非常容易溶解的盐；c)用水或水性介质提取步骤b)中获得的混合物，其中另一碱的盐溶解在水相中，而具有价值的产物或其溶液在适当的溶剂中与辅助碱形成至少一个单独的非水相；d)通过蒸馏从步骤c)中获得的至少一个非水相中去除存在的任何溶剂的至少一部分，形成两个不相溶的液相。