(4-isopropyl-phenyl)-phosphonic acid | 128333-45-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-isopropyl-phenyl)-phosphonic acid
• 英文别名: 1-Isopropyl-benzol-phosphinsaeure-(4)；(4-Isopropyl-phenyl)-phosphonsaeure；Cumol-phosphinsdaeure-(4)；4-Isopropyl-phenylphosphinsaeure；(4-Propan-2-ylphenyl)phosphonic acid
• CAS: 128333-45-9
• 化学式: C₉H₁₃O₃P
• 分子量: 200.174
• InChiKey: WTVNRJZKWMXPJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (4-isopropyl-phenyl)-phosphonic acid 在 potassium permanganate 作用下， 生成 (4-isopropenyl-phenyl)-phosphonic acid
  参考文献：
  名称：

  Micahaelis, Justus Liebigs Annalen der Chemie, 1897, vol. 294, p. 51

  摘要：

  DOI：
• 作为产物：
  描述：

  4-溴异丙苯 在 nickel dichloride 盐酸 作用下， 生成 (4-isopropyl-phenyl)-phosphonic acid
  参考文献：
  名称：

  Studies on Organophosphorus Compounds XL. An One-Pot Procedure for the Mono-O-Alkylation of Phosphonic Acid: A Facile Synthesis of Alkyl Hydrogenp-Substituted Phenylphosphonates

  摘要：

  描述了一种单锅合成六氟氢p-取代苯基膦酸酯4的程序，该方法基于双胺基膦酸3的双(四甲基铵)盐的单-O-烷基化，产率适中。

  DOI：

  10.1055/s-1990-26813

文献信息

• CARBONIC ACID ESTER AND MAGNETIC RECORDING MEDIUM
  申请人：IMAKUNI Akira

  公开号：US20080241599A1

  公开（公告）日：2008-10-02

  A carbonic acid ester is provided that is represented by the formula below and has a melting point of no greater than 0° C. (In the formula, R 1 and R 2 independently denote a saturated hydrocarbon group, R 1 is a branched chain, and R 2 is a straight or branched chain). There is also provided a magnetic recording medium that includes a non-magnetic support and, above the support, at least one magnetic layer including a ferromagnetic powder dispersed in a binder, the magnetic layer including the carbonic acid ester. Furthermore, there is provided a magnetic recording medium including a support and, above the support, a non-magnetic layer including a non-magnetic powder dispersed in a binder, and above the non-magnetic layer, at least one magnetic layer including a ferromagnetic powder dispersed in a binder, the non-magnetic layer and/or the magnetic layer including the carbonic acid ester.

  提供一种碳酸酯，其化学式如下，并且其熔点不大于0°C。（在化学式中，R1和R2分别表示饱和碳氢基团，R1是支链，R2是直链或支链）。还提供了一种磁记录介质，包括非磁性支撑物，在支撑物上方至少有一层包括铁磁粉末分散在粘合剂中的磁性层，该磁性层包括碳酸酯。此外，还提供了一种磁记录介质，包括支撑物，在支撑物上方有一层包括非磁性粉末分散在粘合剂中的非磁性层，以及在非磁性层上方，至少有一层包括铁磁粉末分散在粘合剂中的磁性层，其中非磁性层和/或磁性层包括碳酸酯。
• PHOSPHORUS CONTAINING COMPOUNDS AS PROTEIN KINASE INHIBITORS
  申请人：Hu Baihua

  公开号：US20120220551A1

  公开（公告）日：2012-08-30

  The present invention relates to compounds represented by formula (I), which can modulate the activity of protein kinases. The invention also relates to a composition containing a compound of formula (I), and a method for synthesizing and using such compound for preventing or treating ALK or cMet mediated disorders or conditions.

  本发明涉及由式(I)表示的化合物，可调节蛋白激酶的活性。该发明还涉及含有式(I)化合物的组合物，以及用于合成和使用此类化合物以预防或治疗ALK或cMet介导的疾病或状况的方法。
• Polyactic Acid Resin Composition
  申请人：Ozawa Masaaki

  公开号：US20070299170A1

  公开（公告）日：2007-12-27

  It is an object of the present invention is to provide a polylactic acid resin composition in which a crystal nucleator appropriate for accelerating crystallization of polylactic acid rein is added. A polylactic acid resin composition comprising a polylactic acid resin, and a metal salt of a phosphorus compound of formula (I) wherein R 1 and R 2 may be the same or different and are hydrogen atom, C 1-10 alkyl or C 2-10 alkoxycarbonyl, or a polylactic acid resin composition comprising a polylactic acid resin, and a metal salt of a phosphorus compound of formula (II) wherein R 3 , R 4 , R 5 and R 6 may be the same or different and are hydrogen atom, C 1-10 alkyl or C 2-10 alkoxycarbonyl. The composition is excellent in heat resistance and forming processability.

  本发明旨在提供一种聚乳酸树脂组合物，其中添加了适合加速聚乳酸树脂结晶的晶核剂。该聚乳酸树脂组合物包括聚乳酸树脂和式(I)的磷化合物的金属盐，其中R1和R2可以相同也可以不同，分别是氢原子、C1-10烷基或C2-10烷氧羰基；或者包括聚乳酸树脂和式(II)的磷化合物的金属盐，其中R3、R4、R5和R6可以相同也可以不同，分别是氢原子、C1-10烷基或C2-10烷氧羰基。该组合物具有优异的耐热性和成型加工性。
• CARBONIC ACID ESTER, PRODUCTION PROCESS THEREFOR, AND MAGNETIC RECORDING MEDIUM
  申请人：MORI Masahiko

  公开号：US20080020243A1

  公开（公告）日：2008-01-24

  A process for producing a carbonic acid ester is provided, the process comprising a step of synthesizing a saturated alkyl carbonic acid ester represented by Formula (1) so as to give the saturated alkyl carbonic acid ester represented by Formula (1) as a crude product and a step of subjecting the crude product to liquid-liquid extraction using a saturated hydrocarbon solvent and a solvent comprising an organic solvent that is not infinitely miscible with the saturated hydrocarbon solvent so as to give the saturated alkyl carbonic acid ester represented by Formula (1) as a purified product (in Formula (1), R 1 and R 2 independently denote a saturated hydrocarbon group provided that the sum of the number of carbons in R 1 and the number of carbons in R 2 is at least 12 but no greater than 50). There are also provided a carbonic acid ester produced by the production process, and a magnetic recording medium comprising a non-magnetic support and, above the non-magnetic support, a magnetic layer comprising a ferromagnetic powder dispersed in a binder, the magnetic layer comprising the carbonic acid ester and having on the surface a number of protrusions that satisfies Formula (2) 0.01≦H 15 /H 10 <0.20   (2) (H 10 denotes the number of protrusions per unit area on the surface of the magnetic layer that have a height of less than 10 nm (number/μm 2 ), and H 15 denotes the number of protrusions per unit area on the surface of the magnetic layer that have a height of 15 nm or greater (number/μm 2 )).

  提供了一种制备碳酸酯的工艺，该工艺包括合成由式（1）表示的饱和烷基碳酸酯的步骤，以便将由式（1）表示的饱和烷基碳酸酯作为粗产品，并使用饱和烃溶剂和不与饱和烃溶剂无限混溶的有机溶剂的溶剂进行液-液萃取的步骤，以便将由式（1）表示的饱和烷基碳酸酯作为纯化产品（在式（1）中，R1和R2独立表示饱和烃基，但R1中碳数和R2中碳数之和至少为12但不大于50）。还提供了通过生产工艺生产的碳酸酯，以及包括非磁性支撑和在非磁性支撑上的磁性层的磁记录介质，其中磁性层包括分散在粘合剂中的铁磁性粉末，磁性层包括碳酸酯，并在表面具有满足公式（2）的许多突起0.01≦H15/H10<0.20（2）（其中H10表示磁性层表面每单位面积具有高度小于10 nm的突起的数量（数量/μm2），而H15表示磁性层表面每单位面积具有高度为15 nm或更高的突起的数量（数量/μm2））。
• PRODUCTION PROCESS OF PHOSPHONIC ACID METAL SALT AND THERMOPLASTIC RESIN COMPOSITION CONTAINING PHOSPHONIC ACID METAL SALT
  申请人：Suwa Takeshi

  公开号：US20110196077A1

  公开（公告）日：2011-08-11

  A method for producing a phenylphosphonic acid metal salt, including reacting a phenylphosphonic acid compound (a) with a metal salt, metal oxide or metal hydroxide (b) that is present in an amount beyond the equivalent; a phenylphosphonic acid metal salt composition comprising a phenylphosphonic acid metal salt and surplus metal salt, surplus metal oxide or surplus metal hydroxide produced by the method; and a thermoplastic resin composition comprising the phenylphosphonic acid metal salt composition.

  一种生产苯基膦酸金属盐的方法，包括将苯基膦酸化合物（a）与过量的金属盐、金属氧化物或金属氢氧化物（b）反应，所述金属盐、金属氧化物或金属氢氧化物的量超过当量；一种苯基膦酸金属盐组成物，包括苯基膦酸金属盐和剩余的金属盐、金属氧化物或金属氢氧化物，所述剩余物是由该方法产生的；以及一种热塑性树脂组成物，包括所述苯基膦酸金属盐组成物。