2-二乙酰氨基芴 | 642-65-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 中文名称: 2-二乙酰氨基芴
• 英文名称: 2-Diacetylamino-fluoren
• 英文别名: N-fluoren-2-yl-diacetamide；Diacetyl-fluoren-2-yl-amin；N-Fluoren-2-yl-diacetamid；N-acetyl-N-9H-fluoren-2-ylacetamide；2-diacetylaminofluorene；N-acetyl-N-(9H-fluoren-2-yl)acetamide
• CAS: 642-65-9
• 化学式: C₁₇H₁₅NO₂
• 分子量: 265.312
• InChiKey: CUEUMJJOLJYAPL-UHFFFAOYSA-N

物化性质

• 沸点：
  408.53°C (rough estimate)
• 密度：
  1.0908 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2925190090

反应信息

• 作为产物：
  描述：

  2-氨基芴 、 乙酸酐 生成 2-二乙酰氨基芴
  参考文献：
  名称：

  Morris et al., 1949, vol. 10, p. 1201,1204

  摘要：

  DOI：

文献信息

• PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS
  申请人：WASHINGTON UNIVERSITY

  公开号：EP1233967A1

  公开（公告）日：2002-08-28
• EP1233967A4
  申请人：——

  公开号：EP1233967A4

  公开（公告）日：2003-07-09
• [EN] PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS<br/>[FR] PYRIDINONES POUR LE TRAITEMENT ET LA PREVENTION D'INFECTIONS BACTERIENNES
  申请人：UNIV WASHINGTON

  公开号：WO2001036426A1

  公开（公告）日：2001-05-25

  Novel pyridinones and their derivatives which are effective in treating or preventing Gram-negative bacterial infections are provided. The pyridinones are stable and easily derivatized; the methods by which these derivatizations occur is described. Two regioselective and functional group tolerant methods for the synthesis of the novel pyridiones are also provided. One such sythetic method involves reacting an imine and a Meldrum's acid derivative in solution. The other synthetic method is a solid phase synthetis of the pyridiones in which an imine is prepared bound to a solid support and a Meldrum's acid derivative is reacted with the imine. Novel imine intermediates useful in the solid phase and solution methods of synthesizing the pyridiones are also described.
• Morris et al., 1949, vol. 10, p. 1201,1204
  作者：Morris et al.

  DOI：——

  日期：——

表征谱图