perfluoro-2,2-dimethoxy-3-oxolane | 132182-91-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: perfluoro-2,2-dimethoxy-3-oxolane
• 英文别名: 4,4,5,5-tetrafluoro-2,2-bis(trifluoromethyl)oxolan-3-one
• CAS: 132182-91-3
• 化学式: C₆F₁₀O₂
• 分子量: 294.049
• InChiKey: BMUUHUVWDUJQFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  2,3-bis(fluorosulfato)perfluoro-(2-methylpentane) 在 五氟化锑 作用下， 反应 12.0h， 以87%的产率得到perfluoro-2,2-dimethoxy-3-oxolane
  参考文献：
  名称：

  Electrophilic isomerization of fluoroaliphatic oxygen-containing compounds

  摘要：

  An unusual electrophilic cyclization of fluorine-containing carbonyl compounds and alpha-oxides was discovered. Upon the action of SbF5, perfluorinated ketones, diketones, and alpha-oxides isomerize to oxolanes. This reaction proceeds with the obligatory participation of the terminal CF3 group.

  DOI：

  10.1007/bf00961053

文献信息

• Fluoroaliphatic esters of fluorosulfonic acid. 3. Decomposition of poly(fluorosulfato)perfluoroalkanes under the action of antimony pentafluoride
  作者：V. M. Rogovik、S. D. Chepik、N. I. Delyagina、E. I. Mysov、V. F. Cherstkov、S. R. Sterlin、L. S. German

  DOI：10.1007/bf00958253

  日期：1990.9

  Vicinal bis(fluorosulfato) perfluoroalkanes containing FSO3 groups in the middle of a fluorocarbon chain eliminate one or two molecules of sulfuryl fluoride under the action of SbF5, forming a mixture of isomeric alpha-fluorosulfato ketones and alpha-diketones.
• ROGOVIK, V. M.;CHEPIK, S. D.;DELYAGINA, N. I.;MYSOV, E. I.;CHERSTKOV, V. +, IZV. AN CCCP. CEP. XIM.,(1990) N, S. 2063-2065
  作者：ROGOVIK, V. M.、CHEPIK, S. D.、DELYAGINA, N. I.、MYSOV, E. I.、CHERSTKOV, V. +

  DOI：——

  日期：——
• Electrophilic isomerization of fluoroaliphatic oxygen-containing compounds
  作者：S. D. Chepik、V. F. Cherstkov、E. I. Mysov、A. F. A�rov、M. V. Galakhov、S. R. Sterlin、L. S. German

  DOI：10.1007/bf00961053

  日期：1991.11

  An unusual electrophilic cyclization of fluorine-containing carbonyl compounds and alpha-oxides was discovered. Upon the action of SbF5, perfluorinated ketones, diketones, and alpha-oxides isomerize to oxolanes. This reaction proceeds with the obligatory participation of the terminal CF3 group.