2-异丁基吡咯烷盐酸盐

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 中文名称: 2-异丁基吡咯烷盐酸盐
• 英文名称: Hydron;2-(2-methylpropyl)pyrrolidine;chloride
• 英文别名: hydron;2-(2-methylpropyl)pyrrolidine;chloride
• 化学式: C8H18ClN
• mdl: MFCD03840008
• 分子量: 163.69
• InChiKey: HUHKYHBVDCWROA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.88
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Chiral pyrrolidine derivatives, and methods for preparing compounds thereof
  申请人：Whitten P. Jeffrey

  公开号：US20060025468A1

  公开（公告）日：2006-02-02

  The present invention relates to chiral pyrrolidine derivatives; and methods for preparing compounds thereof. The chiral pyrrolidine derivatives of the present invention may be used as intermediates for pharmaceutical and agricultural chemicals.

  本发明涉及手性吡咯烷衍生物，以及制备其化合物的方法。本发明的手性吡咯烷衍生物可用作制药和农业化学品的中间体。
• Compounds
  申请人：Takeda Pharmaceutical Company Limited

  公开号：US10287286B2

  公开（公告）日：2019-05-14

  The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, Y1, Y2, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

  本发明提供了式 (I) 化合物及其药学上可接受的盐类、 其中X1、X2、X3、Y1、Y2、R1、R2和R3如说明书中所定义，本发明还提供了制备它们的工艺、含有它们的药物组合物以及它们在治疗中的用途。
• CHIRAL PYRROLIDINE DERIVATIVES, AND METHODS FOR PREPARING COMPOUNDS THEREOF
  申请人：Cylene Pharmaceuticals, Inc.

  公开号：EP1778675A1

  公开（公告）日：2007-05-02
• Novel Compounds
  申请人：Takeda Pharmaceutical Company Limited

  公开号：US20180072714A1

  公开（公告）日：2018-03-15

  The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X 1 , X 2 , X 3 , Y 1 , Y 2 , R 1 , R 2 and R 3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
• [EN] CHIRAL PYRROLIDINE DERIVATIVES, AND METHODS FOR PREPARING COMPOUNDS THEREOF<br/>[FR] DÉRIVÉS CHIRAUX DE LA PYRROLIDINE ET PROCÉDÉS SERVANT À PRÉPARER DES COMPOSÉS DE CEUX-CI
  申请人：CYLENE PHARMACEUTICALS

  公开号：WO2006015150A1

  公开（公告）日：2006-02-09

  The present invention relates to chiral pyrrolidine derivatives; and methods for preparing compounds thereof. The chiral pyrrolidine derivatives of the present invention may be used as intermediates for pharmaceutical and agricultural chemicals.