Benzene-1,2,3-trisulfonic acid | 109999-69-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzene-1,2,3-trisulfonic acid
• CAS: 109999-69-1
• 化学式: C₆H₆O₉S₃
• 分子量: 318.3
• InChiKey: MHWVMMHIJHHXQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  188
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• TUMOR TARGETED DRUG COMBRETASTATIN A4 DERIVATIVE
  申请人：Wang Yong

  公开号：US20140128384A1

  公开（公告）日：2014-05-08

  The present invention relates to imidazole, oxazole and thiazole derivatives of tumor-targeted drug combretastatin A4, and phosphate esters, sulfonate esters or pharmaceutically acceptable salts, glycoside derivatives, solvates thereof, wherein the A-ring comprises a 3,5-dimethoxyphenyl group having a substituent at the 4-position. The pharmacological activity assays have demonstrated that the compounds of the present invention have good in vitro anti-tumor activity and excellent tubulin inhibitory effect.

  本发明涉及肿瘤靶向药物康柏他丁A4的咪唑、噁唑和噻唑衍生物，以及磷酸酯、磺酸酯或药用可接受的盐、糖苷衍生物、其溶剂合物，其中A环包括在4位有取代基的3,5-二甲氧基苯基基团。药理活性测定表明，本发明的化合物在体外具有良好的抗肿瘤活性和优秀的微管抑制作用。
• [EN] PROCESS FOR MAKING BUTENYL ESTERS FROM BUTADIENE<br/>[FR] PROCEDE DE FABRICATION D'ESTERS A PARTIR DE BUTADIENE
  申请人：BP CHEM INT LTD

  公开号：WO2003082796A1

  公开（公告）日：2003-10-09

  A process for making a butenyl ester from butadiene by reacting butadiene or a hydrocarbon fraction containing butadiene with a saturated aliphatic monocarboxylic acid, wherein the catalyst is rhenium (VII) oxide or an organic sulphonic acid containing at least (2) sulphonic acid groups per molecule wherein the ratio of the number of carbon atoms to the number of sulphonic acid groups in the organic sulphonic acid is in the range 1 : 1 to 1 : 0.15. Preferred catalysts are organic disulphonic acids for example ethane-1,2-disulphonic acid. The process can be used for making unsaturated esters, or, by hydrogenation of the product, for making saturated esters such as for example butyl acetate. Catalyst can be purified and recycled to the reactor.

  一种从丁二烯中制备丁烯酸酯的方法，包括将丁二烯或含有丁二烯的碳氢化合物与饱和脂肪族一元羧酸反应，其中催化剂为铼（VII）氧化物或含有每个分子至少（2）磺酸基团的有机磺酸，有机磺酸中碳原子数与磺酸基团数的比值在1：1至1：0.15范围内。优选的催化剂是有机二磺酸，例如乙烷-1,2-二磺酸。该方法可用于制备不饱和酯，或通过产物的加氢，用于制备饱和酯，例如醋酸丁酯。催化剂可以被净化并回收到反应器中。
• Organoclay/polymer compositions with flame retardant properties
  申请人：RHEOX, INC.

  公开号：EP1090954A1

  公开（公告）日：2001-04-11

  The present invention is directed to polymer compositions with flame retardant properties that are made from a polymer blended using a defined process with a smectite clay that has been reacted with a specified mixture of organic materials. The inventive compositions have the property that when the organically modified clay is added to the polymer, a composite results which has flame-retardant properties and is based on the finding that degree of dispersion of a smectite organoclay in a polymer matrix will give the compositions flame-retardant properties. Further, it has been found that it is very important to proper functioning of the flame retardant polymer compositions that they have the organoclay dispersed in the polymer such that it is not completely exfoliated.

  本发明是关于具有阻燃性能的聚合物组合物，这种组合物是由一种聚合物与一种已与特定有机材料混合物反应过的直晶石粘土通过特定工艺混合而成的。 本发明的组合物具有这样的特性：当有机改性粘土加入到聚合物中时，会产生一种具有阻燃特性的复合材料，这种复合材料是基于这样的发现：在聚合物基体中，埃克土有机粘土的分散程度会使组合物具有阻燃特性。此外，研究还发现，有机土分散在聚合物中，不会完全剥离，这对阻燃聚合物组合物的正常工作非常重要。
• COMPOSITION AND METHOD FOR FORMING ELECTROACTIVE POLYMER SOLUTION OR COATING COMPRISING CONJUGATED HETEROAROMATIC POLYMER, ELECTROACTIVE POLYMER SOLUTION, OBJECTS COMPRISING THE ELECTROACTIVE COATING, AND SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR FABRICATING THE SAME
  申请人：Polym Technology Corporation

  公开号：EP3375826A1

  公开（公告）日：2018-09-19

  A composition for forming an electroactive coating is described, including an acid as a polymerization catalyst, at least one functional component, and at least one compound of formula (1) as a monomer: wherein X is selected from S, O, Se, Te, PR2 and NR2, Y is hydrogen (H) or a precursor of a good leaving group Y- whose conjugate acid (HY) has a pKa of less than 45, Z is hydrogen (H), silyl, or a good leaving group whose conjugate acid (HY) has a pKa of less than 45, b is 0, 1 or 2, each R1 is a substituent, and the at least one compound of formula (1) includes at least one compound of formula (1) with Z=H and Y≠H.

  描述了一种用于形成电活性涂层的组合物，包括一种作为聚合催化剂的酸、至少一种功能性成分和至少一种作为单体的式 (1) 化合物： 其中 X 选自 S、O、Se、Te、PR2 和 NR2，Y 是氢（H）或共轭酸（HY）的 pKa 小于 45 的良好离去基团 Y- 的前体，Z 是氢（H）、硅烷基、或其共轭酸 (HY) 的 pKa 小于 45 的良好离去基团，b 为 0、1 或 2，每个 R1 为取代基，且至少一种式 (1) 化合物包括至少一种 Z=H 且 Y≠H 的式 (1) 化合物。
• Corrosion inhibiting compositions to mitigate corrosion in environments containing elemental sulfur and/or polysulfides
  申请人：Ecolab USA Inc.

  公开号：US10604710B2

  公开（公告）日：2020-03-31

  A corrosion inhibiting composition is provided which comprises a salt of a fatty acid-amine condensate and an aromatic solvent. The composition can be used in reducing, inhibiting or preventing corrosion of a metal surface used in recovery, transportation, refining or storage of a hydrocarbon fluid containing elemental sulfur or polysulfide.

  提供了一种缓蚀组合物，它由脂肪酸-胺缩合物盐和芳香族溶剂组成。该组合物可用于减少、抑制或防止在回收、运输、提炼或储存含有硫元素或多硫化物的碳氢化合物流体时金属表面的腐蚀。