6-methyl-benzo[b]thiophen-3-ol | 451524-41-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 6-methyl-benzo[b]thiophen-3-ol
• 英文别名: 6-Methyl-1-benzothiophen-3-ol
• CAS: 451524-41-7
• 化学式: C₉H₈OS
• 分子量: 164.228
• InChiKey: RLHUDFJRAFGQMH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  48.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-methyl-benzo[b]thiophen-3-ol 在 双氧水 、 溶剂黄146 作用下， 生成 6-methyl-1,1-dioxo-1λ⁶-benzo[b]thiophen-3-ol
  参考文献：
  名称：

  Reactions with Mercaptans. IV. Reaction of Aromatic Thiols with 3(2H)-Thianaphthenone-1,1-dioxides and 2-Benzylidene-3(2H)-thianaphthenone-1-1-dioxide

  摘要：

  DOI：

  10.1021/ja01570a053
• 作为产物：
  描述：

  3-甲基苯硫酚 在 二硫化碳 、 sodium hydroxide 、 三氯化铝 作用下， 生成 6-methyl-benzo[b]thiophen-3-ol
  参考文献：
  名称：

  Syntheses in the Thionaphthene Series

  摘要：

  DOI：

  10.1021/ja01212a018

文献信息

• Benzo(b)thiophene derivatives and process for producing the same
  申请人：——

  公开号：US20030176490A1

  公开（公告）日：2003-09-18

  The present invention is 3,4-disubstituted-benzo[b]thiophene derivatives represented by general formula (I) and processes for preparing compounds represented by general formula (V) from compounds represented by general formula (IV), preparing a mixture of compounds represented by the following formula (II) and the following formula (III) and preparing the benzo[b]thiophene derivatives represented by the above formula (I). 1 wherein, R 1 and R 2 represent each a halogen atom, a trihalomethyl group, a C 1-4 alkyl group or a C 14 alkoxy group; X represents a hydroxy group or a halogen atom; R 3 and R 4 represent each a hydrogen or a halogen atom, a trihalomethyl group, a C 1-4 alkyl group or a C 1-4 alkoxy group; and R 5 represents a C 1-3 alkyl group or a trifluoromethyl group.

  本发明涉及一种由通式（I）表示的3,4-二取代苯并[b]噻吩衍生物以及从通式（IV）表示的化合物制备通式（V）表示的化合物的过程，制备以下式（II）和以下式（III）表示的化合物的混合物，并制备上述通式（I）表示的苯并[b]噻吩衍生物。其中，R1和R2分别表示卤原子、三卤甲基基团、C1-4烷基基团或C14烷氧基团；X表示羟基或卤原子；R3和R4分别表示氢原子或卤原子、三卤甲基基团、C1-4烷基基团或C1-4烷氧基团；R5表示C1-3烷基基团或三氟甲基基团。
• BENZO b]THIOPHENE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME
  申请人：TEIJIN LIMITED

  公开号：EP1362854A1

  公开（公告）日：2003-11-19

  The present invention is 3,4-disubstituted-benzo[b]thiophene derivatives represented by general formula (I) and processes for preparing compounds represented by general formula (V) from compounds represented by general formula (IV), preparing a mixture of compounds represented by the following formula (II) and the following formula (III) and preparing the benzo[b]thiophene derivatives represented by the above formula (I). wherein, R1 and R2 represent each a halogen atom, a trihalomethyl group, a C1-4 alkyl group or a C1-4 alkoxy group; X represents a hydroxy group or a halogen atom; R3 and R4 represent each a hydrogen or a halogen atom, a trihalomethyl group, a C1-4 alkyl group or a C1-4 alkoxy group; and R5 represents a C1-3 alkyl group or a trifluoromethyl group.

  本发明是通式(I)代表的3,4-二取代-苯并[b]噻吩衍生物，以及从通式(IV)代表的化合物制备通式(V)代表的化合物、制备下式(II)和下式(III)代表的化合物混合物和制备上式(I)代表的苯并[b]噻吩衍生物的工艺。 其中，R1 和 R2 分别代表卤原子、三卤甲基、C1-4 烷基或 C1-4 烷氧基；X 代表羟基或卤原子；R3 和 R4 分别代表氢或卤原子、三卤甲基、C1-4 烷基或 C1-4 烷氧基；R5 代表 C1-3 烷基或三氟甲基。
• Benzo[b]thiophene derivatives
  申请人：Teijin Pharma Limited

  公开号：EP1792614A1

  公开（公告）日：2007-06-06

  The present invention provides 3,4-Disubstituted-benzo[b]thiophene derivatives represented by the following formula (I): wherein, R1 represents a halogen atom, a trihalomethyl group, a C1-4 alkyl group or a C1-4 alkoxy group; and X represents a halogen atom; with the proviso that the compound is not 3-bromomethyl-4-methoxybenzo[b]thiophene, 3-bromomethyl-4-chlorobenzo[b]thiophene, 3-bromomethyl-4-bromobenzo[b]thiophene or 3-bromomethyl-4-fluorobenzo[b]thiophene.

  本发明提供下式（I）所代表的 3,4-二取代-苯并[b]噻吩衍生物： 其中，R1 代表卤素原子、三卤甲基、C1-4 烷基或 C1-4 烷氧基；X 代表卤素原子；但该化合物不是 3-溴甲基-4-甲氧基苯并[b]噻吩、3-溴甲基-4-氯苯并[b]噻吩、3-溴甲基-4-溴苯并[b]噻吩或 3-溴甲基-4-氟苯并[b]噻吩。
• Thioindoxyl derivative and process of making the same
  申请人：DU PONT

  公开号：US02127484A1

  公开（公告）日：1938-08-16
• Process for dyeing cellulose esters and ethers
  申请人：DU PONT

  公开号：US02094597A1

  公开（公告）日：1937-10-05