2-(3-Benzyloxycarbonylamino-4-ethoxycarbonyl-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1isopropylpropyl)acetamide | 159780-57-1
中文名称
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中文别名
——
英文名称
2-(3-Benzyloxycarbonylamino-4-ethoxycarbonyl-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1isopropylpropyl)acetamide
英文别名
Ethyl 1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-2-oxo-6-phenyl-3-(phenylmethoxycarbonylamino)pyridine-4-carboxylate
CAS
159780-57-1
化学式
C36H46F3N3O7Si
mdl
——
分子量
717.858
InChiKey
KCHYHBFIIQPLEZ-UHFFFAOYSA-N
BEILSTEIN
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EINECS
——
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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沸点：749.069±60.00 °C(Press: 760.00 Torr)(predicted)
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密度：1.227±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
计算性质
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辛醇/水分配系数(LogP)：7.53
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重原子数：50
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可旋转键数：16
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环数：3.0
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sp3杂化的碳原子比例：0.44
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拓扑面积：123
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氢给体数：2
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氢受体数：10
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 2-(3-Carboxy-4-ethoxycarbonyl-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1-isopropylpropyl)acetamide 159780-56-0 C29H39F3N2O7Si 612.719 —— 2-(4-Ethoxycarbonyl-3-methoxycarbonyl-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1-isopropylpropyl)acetamide 159780-55-9 C30H41F3N2O7Si 626.745 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 2-(3-Benzyloxycarbonylamino-4-carboxy-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1-isopropylpropyl)acetamide 159780-58-2 C34H42F3N3O7Si 689.804 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-carbamoyl-2-oxo-6-phenylpyridin-3-yl]carbamate 1026743-07-6 C34H43F3N4O6Si 688.819 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-(methylcarbamoyl)-2-oxo-6-phenylpyridin-3-yl]carbamate 1026063-53-5 C35H45F3N4O6Si 702.846 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-(2-ethoxyethylcarbamoyl)-2-oxo-6-phenylpyridin-3-yl]carbamate 1026892-38-5 C38H51F3N4O7Si 760.926 —— benzyl N-[4-[(2-amino-2-oxoethyl)carbamoyl]-1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-2-oxo-6-phenylpyridin-3-yl]carbamate 1027933-50-1 C36H46F3N5O7Si 745.871 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-[[2-(methylamino)-2-oxoethyl]carbamoyl]-2-oxo-6-phenylpyridin-3-yl]carbamate 1025885-69-1 C37H48F3N5O7Si 759.898 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-(2,2-dimethoxyethylcarbamoyl)-2-oxo-6-phenylpyridin-3-yl]carbamate 1026592-89-1 C38H51F3N4O8Si 776.926 —— benzyl N-[4-[[2-(benzylamino)-2-oxoethyl]carbamoyl]-1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-2-oxo-6-phenylpyridin-3-yl]carbamate 1027551-78-5 C43H52F3N5O7Si 835.996 —— Benzyl 2-[[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-2-oxo-6-phenyl-3-(phenylmethoxycarbonylamino)pyridine-4-carbonyl]amino]acetate 1026703-31-0 C43H51F3N4O8Si 836.981 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-[(4-methoxyphenyl)methylcarbamoyl]-2-oxo-6-phenylpyridin-3-yl]carbamate 1027091-79-7 C42H51F3N4O7Si 808.97 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-(2-morpholin-4-ylethylcarbamoyl)-2-oxo-6-phenylpyridin-3-yl]carbamate 1026744-80-8 C40H54F3N5O7Si 801.979 —— benzyl N-[1-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-4-[(2-methyl-1-phenylpropan-2-yl)carbamoyl]-2-oxo-6-phenylpyridin-3-yl]carbamate 1026038-60-7 C44H55F3N4O6Si 821.025 —— N-[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]-2-[3-(2-methyl-1-phenylpropan-2-yl)-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]acetamide 159780-63-9 C37H47F3N4O5Si 712.885 —— 2-[3-(4-Methoxybenzyl)-2,4,8-trioxo-6-phenyl-1,2,3,4,7,8-hexahydropyrido-[3,4-d]pyrimidin-7-yl]-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1-isopropylpropyl)acetamide 159780-59-3 C35H43F3N4O6Si 700.83 —— N-[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]-2-[3-(2,2-dimethoxyethyl)-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]acetamide 1026256-09-6 C31H43F3N4O7Si 668.786 —— 2-[3-[2-(benzylamino)-2-oxoethyl]-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]-N-[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]acetamide 1027080-02-9 C36H44F3N5O6Si 727.856 —— N-[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]-2-[3-(2-morpholin-4-ylethyl)-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]acetamide 1025912-47-3 C33H46F3N5O6Si 693.839 —— N-[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]-2-[3-[2-(methylamino)-2-oxoethyl]-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]acetamide 1026753-61-6 C30H40F3N5O6Si 651.758 —— 2-[7-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-1,1,1-trifluoro-4-methylpentan-3-yl]amino]-2-oxoethyl]-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-3-yl]acetamide 1025904-18-0 C29H38F3N5O6Si 637.731 —— 2-(3-Methyl-2,4,8-trioxo-6-phenyl-1,2,3,4,7,8-hexahydropyrido-[3,4-d]pyrimidin-7-yl)-N-(2-tert-butyldimethylsilyloxy-3,3,3-trifluoro-1-isopropylpropyl)acetamide 159780-61-7 C28H37F3N4O5Si 594.706