4-hydroxy-4'-propyltolane | 107394-89-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-hydroxy-4'-propyltolane
• 英文别名: 4-(4-propylphenylethynyl)phenol；1-(4-hydroxyphenyl)-2-(4-n-propylphenyl)acetylene；4-((4-Propylphenyl)ethynyl)phenol；4-[2-(4-propylphenyl)ethynyl]phenol
• CAS: 107394-89-8
• 化学式: C₁₇H₁₆O
• 分子量: 236.313
• InChiKey: SVODSTPAIRWURL-UHFFFAOYSA-N

物化性质

• 沸点：
  391.8±35.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  对甲苯磺酸 3-丁炔酯 、 4-hydroxy-4'-propyltolane 在 potassium carbonate 作用下， 以 丁酮 为溶剂， 生成 1-But-3-ynoxy-4-[2-(4-propylphenyl)ethynyl]benzene
  参考文献：
  名称：

  Nematic tolanes and acetylenes

  摘要：

  据报道，首次发现了在末端链中包含非共轭碳-碳三键并在熔点以上呈现向列相的液晶。为了研究液晶末端链的形状、构象和刚性对其介晶相行为的影响，合成了一系列在末端链中或两个苯环之间包含碳-碳三键的化合物。此外，还制备了一系列相关的托兰化合物，其在末端取代基为含额外碳-碳双键的烯氧链或简单的烷氧链，用于比较研究。

  DOI：

  10.1039/b209045g
• 作为产物：
  描述：

  1-(4-acetoxyphenyl)-2-(4-n-propylphenyl)acetylene 生成 4-hydroxy-4'-propyltolane
  参考文献：
  名称：

  Optically active compound and photosensitive resin composition

  摘要：

  一种光活性化合物与光敏剂结合使用，由以下公式（1）表示： A −[( J ) m −( X-Pro )] n (1) 其中，A代表至少包括一种从烃基和杂环基中选择的疏水基的疏水单元，J代表连接基团，X-Pro代表由光照可去除的保护基团Pro保护的亲水基团，m代表0或1，n代表不少于1的整数。 保护基团Pro可以与光敏剂（特别是光酸发生剂）一起通过光照可去除，也可以是疏水保护基团。亲水基团可以是羟基或羧基。光活性化合物对短波长光源具有很高的敏感性，用于光刻应用，因此，该光活性化合物有利于形成具有高分辨率的图案。

  公开号：

  US20030211421A1

文献信息

• Nematic 2,5-disubstituted thiophenesElectronic supplementary information (ESI) available: extensive synthetic information. See http://www.rsc.org/suppdata/jm/b2/b202073b/
  作者：Neil L. Campbell、Warren L. Duffy、Gareth I. Thomas、Janine H. Wild、Stephen M. Kelly、Kevin Bartle、Mary O'Neill、Vicky Minter、Rachel P. Tuffin

  DOI：10.1039/b202073b

  日期：2002.8.30

  A large number of new liquid crystals incorporating the 2,5-disubstituted thiophene ring have been prepared and their mesomorphic behaviour studied in order to systematically investigate the correlation between the molecular structure and mesomorphism of thiophene derivatives with different shapes, polarisability and polarity. As a consequence of these investigations we have prepared a new class of liquid crystals incorporating a 2,5-disubstituted thiophene ring and a conjugated trans-carbon–carbon double bond in the terminal chain. These novel thiophene derivatives are the first liquid crystals incorporating a 2,5-disubstituted thiophene ring to exhibit a nematic phase at room temperature. This enables the flexoelectric coefficients of a bent-shaped molecule to be measured directly and at room temperature for the first time to the authors' knowledge. Many of these new thiophenes exhibit a high birefringence and a high nematic clearing point and are of potential use as components of nematic mixtures in LCDs.

  制备了大量含有2,5-二取代噻吩环的新型液晶，并研究了它们的介晶行为，以系统地探讨不同形状、极化能力和极性的噻吩衍生物的分子结构与介晶性之间的关联。通过这些研究，我们合成了一类新型液晶，它们含有2,5-二取代噻吩环和末端链中的共轭反式碳-碳双键。这些新颖的噻吩衍生物是首批在室温下表现出向列相的含有2,5-二取代噻吩环的液晶。这使得弯曲形状分子的挠曲电系数能够首次在作者所知的情况下直接在室温下测量。许多这些新型噻吩具有高双折射率和高向列相清亮点，有可能作为液晶显示器中向列相混合物的成分。
• OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION
  申请人：Kansai Research Institute, Inc.

  公开号：EP1375463A1

  公开（公告）日：2004-01-02

  A photoactive compound is used in combination with a photosensitizer, represented by the following formula (1):         A-[(J)m-(X-Pro)]n     (1)    wherein A represents a hydrophobic unit comprising at least one kind of hydrophobic groups selected from a hydrocarbon group and a heterocyclic group, J represents a connecting group, X-Pro represents a hydrophilic group protected by a protective group Pro which is removable by light exposure, m represents 0 or 1, and n represents an integer of not less than 1. The protective group Pro may be removable by light exposure in association with the photosensitizer (especially, a photo acid generator), or may be a hydrophobic protective group. The hydrophilic group may be a hydroxyl group or a carboxyl group. The photoactive compound has high sensitivity to a light source of short wavelength beams, for resist application, therefore, the photoactive compound is advantageously used for forming a pattern with high resolution.

  光活性化合物与光敏剂结合使用，光敏剂由下式（1）表示： A-[(J)m-(X-Pro)]n (1) 其中 A 代表疏水单元，包括至少一种选自烃基和杂环基的疏水基团；J 代表连接基团；X-Pro 代表亲水基团，该亲水基团受保护基团 Pro 的保护，该保护基团可通过光照去除；m 代表 0 或 1；n 代表不小于 1 的整数。 保护基 Pro 可以通过与光敏剂（特别是光酸发生器）一起进行光照射而去除，也可以是疏水保护基。亲水基团可以是羟基或羧基。光活性化合物对短波长光束的光源具有很高的灵敏度，因此在抗蚀剂应用中，光活性化合物可用于形成具有高分辨率的图案。
• Tolane, Verfahren zu ihrer Herstellung sowie ihre Verwendung
  申请人：Merck Patent GmbH

  公开号：EP1731587A1

  公开（公告）日：2006-12-13

  Die vorliegende Erfindung betrifft Tolane der allgemeinen Formel I worin Y H, eine Acyl-, Sulfonyl- oder Oxycarbonyl-Schutzgruppe bedeutet und L1, L2, r, s, Z1, A1, m und R1 die in Anspruch 1 angegebenen Bedeutungen aufweisen, Verfahren zu ihrer Herstellung sowie ihre Verwendung in der Synthese von flüssigkristallinen Tolanen und polymerisierbaren, flüssigkristallinen Tolanen.

  本发明涉及通式 I 的对甲苯磺酸盐 其中 Y 是 H、酰基、磺酰基或氧羰基保护基团，L1、L2、r、s、Z1、A1、m 和 R1 具有权利要求 1 中给出的含义；本发明涉及其制备工艺及其在合成液晶对甲苯磺酸盐和可聚合液晶对甲苯磺酸盐中的用途。
• Liquid-crystal composition and liquid-crystal element
  申请人：JNC Corporation

  公开号：EP2698415A2

  公开（公告）日：2014-02-19

  The current application provides a liquid crystal composition, which is component of an optically isotropic liquid crystal composition including chiral dopant used in an element driven in a state of an optically isotropic liquid crystal phase, wherein in the liquid crystal composition the difference between the upper limit and the lower limit of a temperature allowing coexistence of a chiral nematic phase and a non-liquid crystalline isotropic phase or coexistence of a nematic phase and a non-liquid crystalline isotropic phase is 3°C to 150°C, as well as a liquid crystal element comprising said liquid crystal composition.

  本申请提供了一种液晶组合物，它是光学各向同性液晶组合物的组分，包括在光学各向同性液晶相状态下驱动元件中使用的手性掺杂剂、其中，在液晶组合物中，允许手性向列相和非液晶各向同性相共存或向列相和非液晶各向同性相共存的温度上限和下限之差为 3°C 至 150°C，以及包含所述液晶组合物的液晶元件。
• Nematic Liquid Crystals with a Trifluoromethyl Group
  作者：Stephen M. Kelly、Graham Skelton、Cliff Jones、Vicki Minter、Rachel Tuffin

  DOI：10.1080/10587250108025060

  日期：2001.8

  We have synthesised a new class of compounds incorporating a trifluoromethyl group in the terminal alkoxy or alkenyloxy chain. Compounds containing several aromatic rings were synthesised with a view to producing compounds of high birefringence. This also included the synthesis of compounds containing a carbon-carbon triple bond. Compounds with three 1,4-disubstituted rings were synthesised in order to produce materials with a high nematic clearing point and as low a melting point as possible. Laterally fluoro-substituted compounds were prepared to generate a high positive value of the dielectric anisotropy, a low melting point and no smectic mesophases. Substances containing a cyclohexyl ring, which tend to induce a lower viscosity and compounds incorporating a bicyclo[2.2.2]octane ring were also synthesised in order to produce a high nematic clearing point and to influence the elastic constants. The (E)-trifluorobut-2-enyloxy-compounds were prepared in attempts to produce compounds with appropriate elastic constants and a high birefringence.