1-methyl-2-(4-nitrophenoxy)ethylamine | 66145-42-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-methyl-2-(4-nitrophenoxy)ethylamine
• 英文别名: 2-Amino-4-nitro-propoxybenzene；1-(4-nitrophenoxy)propan-2-amine
• CAS: 66145-42-4
• 化学式: C₉H₁₂N₂O₃
• 分子量: 196.206
• InChiKey: QETOSXISZOAWEJ-UHFFFAOYSA-N

物化性质

• 沸点：
  346.9±22.0 °C(Predicted)
• 密度：
  1.208±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  81.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-methyl-2-(4-nitrophenoxy)ethylamine 、 4-(2,3-epoxypropyloxy)-isocarbostyril 以 甲醇 为溶剂， 生成 4-[3-{1-methyl-2-(4-nitrophenoxy) ethylamino}-2-hydroxypropoxy]isocarbostyril
  参考文献：
  名称：

  Isocarbostyril derivatives

  摘要：

  本文描述了具有结构##STR1##的化合物，其中X、R.sub.1、R.sub.2、R.sub.3、R.sub.4和R.sub.5如所定义，对β-受体阻滞剂和降压剂具有有效作用。

  公开号：

  US04526893A1

文献信息

• Amino-acid amide derivatives, agricultural or horticultural fungicides,
  申请人：Kumiai Chemical Industry Co., Ltd.

  公开号：US05574064A1

  公开（公告）日：1996-11-12

  The present invention provides an agricultural or horticultural fungicide including an effective amount of an amino-acid derivative represented by the formula: ##STR1## wherein R.sup.1 represents a lower alkyl group (optionally having at least one same or different substituent of a halogen atom, an alkoxy group, and a cyano group), R.sup.2 represents an ethyl group, or an n-propyl group, R.sup.3 represents a hydrogen atom or a lower alkyl group, R.sup.4 represents a hydrogen atom, R.sup.5, R.sup.6, and R.sup.7 independently represent a hydrogen atom or a lower alkyl group, R.sup.8 represents a hydrogen atom, or a lower alkyl group, Z.sup.1 and Z.sup.2 independently represent an oxygen atom or a sulfur atom, Z.sup.3 represents an oxygen atom, or a sulfur atom, Q represents a phenyl group, m represents an integer from 0 to 2, and n represents 0 or 1. The amino-acid amide derivatives according to the present invention exhibit superior control of cucumber downy mildew (Pseudoperonospora cubensis), tomato late blight (Phytophthora infestans), and grape downy mildew (Plasmopara viticola), and are effective for potato late blight (Phytophthora infestans). In addition, the agricultural or horticultural fungicides of the present invention are also characterized in that they are not harmful chemicals and exhibit excellent characteristics such as systemic action, residual activity, and persistence after rain-fall.

  本发明提供了一种农业或园艺杀菌剂，包括一种由以下式表示的氨基酸衍生物的有效量：##STR1##其中R.sup.1代表较低的烷基基团（可选地至少具有一个相同或不同的卤原子、烷氧基和氰基取代基），R.sup.2代表乙基基团或正丙基基团，R.sup.3代表氢原子或较低的烷基基团，R.sup.4代表氢原子，R.sup.5、R.sup.6和R.sup.7独立地代表氢原子或较低的烷基基团，R.sup.8代表氢原子或较低的烷基基团，Z.sup.1和Z.sup.2独立地代表氧原子或硫原子，Z.sup.3代表氧原子或硫原子，Q代表苯基，m代表从0到2的整数，n代表0或1。根据本发明的氨基酸酰胺衍生物表现出对黄瓜霜霉病（Pseudoperonospora cubensis）、番茄晚疫病（Phytophthora infestans）和葡萄霜霉病（Plasmopara viticola）的优越控制，并且对马铃薯晚疫病（Phytophthora infestans）有效。此外，本发明的农业或园艺杀菌剂还具有不含有害化学物质的特点，并表现出系统作用、残留活性和雨后持久性等优异特性。
• Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them
  申请人：NISSHIN FLOUR MILLING CO., LTD.

  公开号：EP0113910A1

  公开（公告）日：1984-07-25

  Isocarbostyril derivative represented by the general formula wherein R, denotes hydrogen atom or a lower alkyl group, R2 and R3 denote hydrogen atom or a lower alkyl group, respectively R4 and R5 denote hydrogen atom, halogen atom, a lower alkyl group, lower alkoxy group, hydroxy group, amino group, lower acylamino group, nitro group, lower alkylmercapto group, carbamoyl group, sulfamoyl group or hydroxyalkyl group, respectively, and X denotes oxygen atom, sulfur atom or imino group, and salts thereof and a pharmaceutically composition comprising the above compound as active ingredient.

  由通式表示的异卡波特利衍生物 其中 R，表示氢原子或低级烷基，R2 和 R3 分别表示氢原子或低级烷基，R4 和 R5 分别表示氢原子、卤素原子、低级烷基、低级烷氧基、羟基、氨基、低级酰氨基、硝基、低级烷基巯基、氨基甲酰基、氨基磺酰基或羟烷基，X 表示氧原子、硫原子或亚氨基，及其盐类和以上述化合物为有效成分的药物组合物。
• AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS
  申请人：KUMIAI CHEMICAL INDUSTRY CO., LTD.

  公开号：EP0648740B1

  公开（公告）日：1997-10-08
• US4526893A
  申请人：——

  公开号：US4526893A

  公开（公告）日：1985-07-02
• US5574064A
  申请人：——

  公开号：US5574064A

  公开（公告）日：1996-11-12