phenethyl-(10-thioxo-10H-9-oxa-10λ5-phosphaphenanthren-10-yl)amine | 1312947-06-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenethyl-(10-thioxo-10H-9-oxa-10λ5-phosphaphenanthren-10-yl)amine
• 英文别名: N-(2-phenylethyl)-6-sulfidobenzo[c][2,1]benzoxaphosphinin-6-ium-6-amine
• CAS: 1312947-06-0
• 化学式: C₂₀H₁₈NOPS
• 分子量: 351.409
• InChiKey: FNBCUDJMGAKFHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  26.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  10-氯-9,10-二氢-9-氧杂-10-磷杂菲 在 氯仿 、 硫化氢 、 三乙胺 、 sodium hydroxide 作用下， 以 四氯化碳 、 水 、 甲苯 为溶剂， 生成 phenethyl-(10-thioxo-10H-9-oxa-10λ5-phosphaphenanthren-10-yl)amine
  参考文献：
  名称：

  新型硫代磷环分子6H-二苯并[c,e][1,2]氧代膦6-硫化物的合成及反应性

  摘要：

  The new 6H-dibenzo[c,e][1,2]oxaphosphinine 6-sulfide (1) was synthesized and characterized by H-1-, C-13-, P-31-NMR, IR spectroscopy as well as X-ray diffraction and HR-MS. The reactivity of (1) was investigated with a series of test reactions, including Michael-type additions and the Atherton-Todd-reaction and finally compared to that of the parent 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide.

  DOI：

  10.3987/com-10-12124

文献信息

• Synthesis of new organophosphorus compounds using the atherton-todd reaction as a versatile tool
  作者：Sebastian Wagner、Muriel Rakotomalala、Yana Bykov、Olaf Walter、Manfred Döring

  DOI：10.1002/hc.21006

  日期：——

  molecules are important and versatile compounds, for a broad field of applications, novel synthetic approaches are of interest to both academia and industry. As an example, the single-step synthesis of the bridged 1,3-phenylene bis(diphenylphosphinate) with potential flame-retardant properties was added to this study. In addition, the reaction is utilized for the synthesis of a novel organophosphorus

  本文讨论了七种有机磷化合物在 Atherton-Todd 条件下的行为。因此，系统研究了不同（苯）氧杂膦、二氧杂膦、二氧杂膦和二苯基氧化膦与三种亲核试剂的反应性和选择性。结果证明了 Atherton-Todd 反应对具有不同磷环境和反应性 PH 键的各种有机磷化合物的多功能性。本文研究的亲核试剂被选为胺类和醇类的模型底物。由于有机磷分子是重要且用途广泛的化合物，因此对于广泛的应用领域，学术界和工业界都对新的合成方法感兴趣。例如，桥接 1 的单步合成，具有潜在阻燃性能的 3-亚苯基双（二苯基次膦酸盐）被添加到该研究中。此外，该反应还用于合成新型有机磷酐。© 2012 Wiley Periodicals, Inc. 杂原子化学 23:216–222, 2012; 在 wileyonlinelibrary.com 上在线查看这篇文章。DOI 10.1002/hc.21006
• Synthesis and Reactivity of 6H-Dibenzo[c,e][1,2]oxaphosphinine 6-Sulfide, a Novel Thiophosphacyclic Molecule
  作者：Manfred Döring、Sebastian Wagner、Thomas Zevaco、Michael Ciesielski、Olaf Walter、Muriel Rakotomalala

  DOI：10.3987/com-10-12124

  日期：——

  The new 6H-dibenzo[c,e][1,2]oxaphosphinine 6-sulfide (1) was synthesized and characterized by H-1-, C-13-, P-31-NMR, IR spectroscopy as well as X-ray diffraction and HR-MS. The reactivity of (1) was investigated with a series of test reactions, including Michael-type additions and the Atherton-Todd-reaction and finally compared to that of the parent 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide.