2,4-dichloro-N-ethyl benzamide | 66896-66-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-dichloro-N-ethyl benzamide
• 英文别名: 2,4-dichlorobenzoylethylamide；2,4-dichloro-N-ethylbenzamide
• CAS: 66896-66-0
• 化学式: C₉H₉Cl₂NO
• mdl: MFCD00460594
• 分子量: 218.083
• InChiKey: HGHGYRAEXXRLJV-UHFFFAOYSA-N

物化性质

• 沸点：
  316.3±32.0 °C(Predicted)
• 密度：
  1.281±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.222
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  间甲苯磺酰氯 、 2,4-dichloro-N-ethyl benzamide 生成
  参考文献：
  名称：

  DE2744137

  摘要：

  公开号：

文献信息

• PROCESS FOR ALKENYLATING CARBOXAMIDES
  申请人：Staffel Wolfgang

  公开号：US20090131657A1

  公开（公告）日：2009-05-21

  The present invention relates to a process for preparing N-(1-alkenyl)carboxamides of the formula I, which comprises reacting a carboxamide of the formula II with an alkyne of the formula III in the presence of a catalyst selected from among carbonyl complexes, halides and oxides of rhenium, manganese, tungsten, molybdenum, chromium and iron.

  本发明涉及一种制备式I的N-(1-烯基)羧酰胺的方法，包括在选择自铼、锰、钨、钼、铬和铁的羰基配合物、卤化物和氧化物之一作为催化剂的情况下，将式II的羧酰胺与式III的炔烃反应。
• Carbacyclin analogues
  申请人：THE UPJOHN COMPANY

  公开号：EP0159784A1

  公开（公告）日：1985-10-30

  A compound of the formula and intermediates useful in preparing same.

  一种化合物的公式及其制备过程中有用的中间体。
• Fungicides for the control of take-all disease of plants
  申请人：Monsanto Company

  公开号：US20010046975A1

  公开（公告）日：2001-11-29

  A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula 1 wherein Z 1 and Z 2 are C or N and are part of an aromatic ring selected from benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole, and isothiazole; A is selected from —C(X)-amine, —C(O)—SR 3 , —NH—C(X)R 4 , and —C(═NR )—XR 7 ; B is —W m —Q(R 2 ) 3 or selected from o-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R 4 ; Q is C, Si, Ge, or Sn; W is —C(R 3 ) p H (2-p) —; or when Q is C, W is selected from —C(R 3 ) p H (2-p) —, —N(R 3 ) m H (1-m) —, —S(O) p —, and —O—; X is O or S; n is 0, 1, 2, or 3; m is 0 or 1; p is 0, 1, or 2; each R is independently selected from a) halo, formyl, cyano, amino, nitro, thiocyanato, isothiocyanato, trimethylsilyl, and hydroxy; b) C1-C4 alkyl, alkenyl, alkynyl, C3-C6 cycloalkyl, and cycloalkenyl, each optionally substituted with halo, hydroxy, thio, amino, nitro, cyano, formyl, phenyl, C1-C4 alkoxy, alkylcarbonyl, alkylthio, alkylamino, dialkylamino, alkoxycarbonyl, (alkylthio)carbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkylsulfinyl, or alkylsulfonyl; c) phenyl, furyl, thienyl, pyrrolyl, each optionally substituted with halo, formyl, cyano, amino, nitro, C1-C4 alkyl, alkenyl, alkynyl, alkoxy, alkylthio, alkylamino, dialkylamino, haloalkyl, and haloalkenyl; d) C1-C4 alkoxy, alkenoxy, alkynoxy, C3-C6 cycloalkyloxy, cycloalkenyloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, dialkylamino, alkylcarbonylamino, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkylcarbonyl, alkylcarbonyloxy, alkoxycarbonyl, (alkylthio)carbonyl, phenylcarbonylamino, phenylamino, each optionally substituted with halo; wherein two R groups may be combined to form a fused ring; each R 2 is independently selected from alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl and phenyl, each optionally substituted with R 4 or halogen; and wherein, when Q is C, R 2 may also be selected from halo, alkoxy, alkylthio, alkylamino, and dialkylamino; wherein two R 2 groups may be combined to form a cyclo group with Q; R 3 is C1-C4 alkyl; R 4 is C1-C4 alkyl, haloalkyl, alkoxy, alkylthio, alkylamino, or dialkylamino; and R 7 is C1-C4 alkyl, haloalkyl, or phenyl, optionally substituted with halo, nitro, or R 4 ; or an agronomic salt thereof.

  通过在种子播种前，优选地向种子施用公式1的杀菌剂来控制植物的扁腐病，其中Z1和Z2是C或N，是从苯，吡啶，噻吩，呋喃，吡咯，吡唑，噻唑和异噻唑中选择的芳香环的一部分；A是从—C（X）-胺，—C（O）—SR3，—NH—C（X）R4和—C（═NR）—XR7中选择的；B是—Wm—Q（R2）3或从o-甲苯基，1-萘基，2-萘基和9-菲基中选择的，每个都可以用卤素或R4取代；Q是C，Si，Ge或Sn；W是—C（R3）pH（2-p）—；或当Q是C时，W从—C（R3）pH（2-p）—，—N（R3）mH（1-m）—，—S（O）p—和—O—中选择；X是O或S；n是0，1，2或3；m是0或1；p是0，1或2；每个R是独立选择的，从a）卤素，酰基，氰基，氨基，硝基，硫氰酸基，异硫氰酸基，三甲基硅基和羟基中选择；b）C1-C4烷基，烯基，炔基，C3-C6环烷基和环烯基，每个都可以用卤素，羟基，硫，氨基，硝基，氰基，酰基，苯基，C1-C4烷氧基，烷基羰基，烷基硫基，烷基氨基，二烷基氨基，烷氧羰基，（烷硫）羰基，烷基氨基羰基，二烷基氨基羰基，烷基亚砜基或烷基磺酰基取代；c）苯基，呋喃基，噻吩基，吡咯基，每个都可以用卤素，酰基，氰基，氨基，硝基，C1-C4烷基，烯基，炔基，烷氧基，烷基硫基，烷基氨基，二烷基氨基，卤代烷基和卤代烯基取代；d）C1-C4烷氧基，烯氧基，炔氧基，C3-C6环烷氧基，环烯氧基，烷基硫基，烷基亚砜基，烷基磺酰基，烷基氨基，二烷基氨基，烷基羰基氨基，氨基羰基，烷基氨基羰基，二烷基氨基羰基，烷基羰基，烷基羰氧基，烷氧羰基，（烷硫）羰基，苯基羰基氨基，苯基氨基，每个都可以用卤素取代；其中两个R基可以结合形成融合环；每个R2是独立选择的，从烷基，烯基，炔基，环烷基，环烯基和苯基中选择，每个都可以用R4或卤素取代；当Q为C时，R2还可以选择自卤素，烷氧基，烷基硫基，烷基氨基和二烷基氨基；其中两个R2基可以结合形成带有Q的环；R3是C1-C4烷基；R4是C1-C4烷基，卤代烷基，烷氧基，烷基硫基，烷基氨基或二烷基氨基；R7是C1-C4烷基，卤代烷基或苯基，可以选择自卤素，硝基或R4取代；或其农学盐。
• 9-Substituted carbacyclin analogues
  申请人：THE UPJOHN COMPANY

  公开号：EP0086611A1

  公开（公告）日：1983-08-24

  Novel compounds of the following general formula: wherein R is -CN; -CH2X wherein X is chloro or bromo; -CH=CH2; -CHO; -CH20H; -C≡CH; -C≡C-CF3; -C≡C-CnH2nCH3 wherein n is zero, one, 2 or 3; cis-CH=CHCnH2nCH3 or trans -CH=CHCnH2nCH3 wherein n is zero, one, 2 or 3; -CH=C(X')2 wherein X' is fluoro, chloro, or bromo; cis-CH=CHX' or trans-CH=CHX' wherein X' is fluoro, chloro, or bromo;-C≡C-C≡CR1 wherein R1 is hydrogen, methyl, or ethyl; -C≡COR2 wherein R2 is methyl or ethyl; and intermediates for their preparation.

  以下通式的新型化合物： 其中 R 是 -CN；-CH2X，其中 X 是氯或溴；-CH=CH2；-CHO；-CH20H；-C≡CH；-C≡C-CF3；-C≡C-CnH2nCH3，其中 n 是零、1、2 或 3；顺式-CH=CHCnH2nCH3 或反式-CH=CHCnH2nCH3，其中 n 是零、1、2 或 3；顺式-CH=C(X')2，其中 X'为氟、氯或溴；顺式-CH=CHX'或反式-CH=CHX'，其中 X'为氟、氯或溴；-C≡C-C≡CR1，其中 R1 为氢、甲基或乙基；-C≡COR2，其中 R2 为甲基或乙基；以及用于制备它们的中间体。
• Benzopyrans
  申请人：THE UPJOHN COMPANY

  公开号：EP0088619A2

  公开（公告）日：1983-09-14

  Compounds of the formula wherein the 11 and 12-substituents correspond to prosta- groups and 12-sidechams, respectively, and the corresponds to prostagiandin C atoms 1 to 4 (Q a carboxyl function or derivative thereof). These can nave pharmacological activity. Novel inter- are also disclosed.

  这些化合物可以具有药理活性。 此外，还公开了新的互作化合物。