1,2-epoxy-1-phenylpentane | 174953-29-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2-epoxy-1-phenylpentane
• 英文别名: cis-2-Propyl-3-phenyl-oxiran；trans-beta-Propylstyrene 7,8-oxide；(2S,3R)-2-phenyl-3-propyloxirane
• CAS: 174953-29-8
• 化学式: C₁₁H₁₄O
• 分子量: 162.232
• InChiKey: VGLOFKUDCAPVAL-MNOVXSKESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-pentenylbenzene 在 邻苯二甲酸二辛酯 作用下， 反应 24.0h， 生成 1,2-环氧-1-苯基戊烷 、 1,2-epoxy-1-phenylpentane
  参考文献：
  名称：

  Asymmetric epoxidation of styrene derivatives by styrene monooxygenase from Pseudomonas sp. LQ26: effects of α- and β-substituents

  摘要：

  Recombinant Escherichia coli expressing a styrene monooxygenase, StyAB2, from Pseudomonas sp. LQ26 was applied to synthesize a range of chiral epoxides from conjugated styrene derivatives with excellent (>99%) enantioselectivity in most cases. The substrate preference was studied with a special focus on the steric effect of alpha- and beta-substituents. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.12.022

文献信息

• Asymmetric epoxidation of styrene derivatives by styrene monooxygenase from Pseudomonas sp. LQ26: effects of α- and β-substituents
  作者：Hui Lin、Yan Liu、Zhong-Liu Wu

  DOI：10.1016/j.tetasy.2010.12.022

  日期：2011.1

  Recombinant Escherichia coli expressing a styrene monooxygenase, StyAB2, from Pseudomonas sp. LQ26 was applied to synthesize a range of chiral epoxides from conjugated styrene derivatives with excellent (>99%) enantioselectivity in most cases. The substrate preference was studied with a special focus on the steric effect of alpha- and beta-substituents. (C) 2011 Elsevier Ltd. All rights reserved.