1-(Fluoromethyl)pyridinium | 107147-87-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-(Fluoromethyl)pyridinium
• 英文别名: 1-(fluoromethyl)pyridin-1-ium
• CAS: 107147-87-5
• 化学式: C6H7FN+
• 分子量: 112.12
• InChiKey: VSUWJVLTQUOKSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• One step removal of unwanted molecules from circulating blood
  申请人：Advanced Extravascular Systems

  公开号：US20040161736A1

  公开（公告）日：2004-08-19

  The present invention provides a method, and resulting product, for the removal of unwanted molecules from a host's blood using a one-step procedure. The unwanted molecules may be anti-A blood protein and/or anti-B blood protein antibodies that would otherwise cause host rejection of transplanted organs or tissues from a source having a different ABO blood type. The unwanted molecules may also be excess antibodies, or virions, present in a diseased host.

  本发明提供了一种用一步法从宿主血液中清除不需要的分子的方法及其产品。不需要的分子可能是抗 A 型血蛋白和/或抗 B 型血蛋白抗体，否则会导致宿主对来自不同 ABO 血型的移植器官或组织产生排斥反应。不需要的分子也可能是存在于患病宿主体内的过量抗体或病毒。
• ONE STEP REMOVAL OF UNWANTED MOLECULES FROM CIRCULATING BLOOD
  申请人：Advanced Extravascular Systems

  公开号：EP1315551B1

  公开（公告）日：2015-11-04
• ONE STEP REMOVAL OF SELECTED MOLECULES FROM BODY FLUID AND TISSUE
  申请人：Advanced Extravascular System Inc.

  公开号：EP2585082A2

  公开（公告）日：2013-05-01
• Imprinting a substrate for separation of a target molecule from a fluid medium
  申请人：Belfort J. Georges

  公开号：US20070128423A1

  公开（公告）日：2007-06-07

  The present invention is directed to a method of producing a substrate suitable for separation of a target molecule from a fluid medium. This method includes providing an emulsion comprising a water phase in an oil phase, where the oil phase contains a polymerizable monomer and the water phase contains the target molecule. The substrate, having pores extending from one side of the substrate to another side of the substrate, is coated with the emulsion, and the monomer in the emulsion coated substrate is then polymerized. The water and target molecule are removed from the polymerized, emulsion coated substrate. As a result, the substrate is imprinted with the target molecule and, therefore, is suitable for separation of the target molecule from a fluid medium. The resulting article and its use are also disclosed.
• One step removal of selected molecules from body fluid and tissue
  申请人：Bristow Duke K.

  公开号：US20110250287A1

  公开（公告）日：2011-10-13

  A method for reducing the number of selected antibodies in a subject's blood, the method comprising removing blood from the subject, passing the blood along an enclosed pathway, wherein the pathway comprises one or more semi-permeable hollow fibers with one or more membranes having surfaces positioned substantially perpendicular to the length of the one or more hollow fiber and antigens specific for the antibodies immobilized on the one or more membranes, returning the treated blood to the internal circulation of the subject, wherein the returned treated blood has a reduced number of selected antibodies compared to before treatment.