1-Methyl-4-isopropenyl-3α-(2.6.-dihydroxy-3-carboxy-4-pentyl-phenyl)-cyclohexen-(1) | 1244-58-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Methyl-4-isopropenyl-3α-(2.6.-dihydroxy-3-carboxy-4-pentyl-phenyl)-cyclohexen-(1)
• 英文别名: 2,4-dihydroxy-3-[(1S,6S)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-6-pentylbenzoic acid
• CAS: 1244-58-2；19206-65-6
• 化学式: C₂₂H₃₀O₄
• 分子量: 358.478
• InChiKey: WVOLTBSCXRRQFR-SJORKVTESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] PLATINUM COMPLEX ANTI-NEOPLASTIC AGENTS COMPRISING A CANNABINOID LIGAND<br/>[FR] AGENTS ANTINÉOPLASIQUES COMPLEXES DE PLATINE COMPRENANT UN LIGAND CANNABINOÏDE
  申请人：DIVERSE BIOTECH INC

  公开号：WO2021034405A1

  公开（公告）日：2021-02-25

  This disclosure provides platinum complex anti-neoplastic agents that comprise at least one cannabinoid ligand as either a leaving ligand or an axial ligand. After the agent enters the cell, the cannabinoid ligand is released as a cannabinoid, where the cannabinoid can then provide additional therapeutic benefits.

  本发明提供了至少包含一个大麻素配体作为离去配体或轴向配体的铂配合物抗肿瘤剂。当该药剂进入细胞后，大麻素配体将作为大麻素释放出来，大麻素可以提供额外的治疗效益。
• [EN] CONJUGATE MOLECULES<br/>[FR] MOLÉCULES CONJUGUÉES
  申请人：DIVERSE BIOTECH INC

  公开号：WO2021076197A1

  公开（公告）日：2021-04-22

  This disclosure provides multifunctional conjugate molecules comprising a target binding component covalently linked to one or more cannabinoids and/or one or more cannabinoid conjugate components. In some embodiments, the target binding component also is covalently linked to one or more active agent components. The disclosed conjugate molecules are designed to deliver therapeutic benefits of each component of the conjugate molecules and can be used to treat cancer and other disorders.