1-(4-Hydroxy-3-methylphenyl)propan-2-one | 88659-81-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4-Hydroxy-3-methylphenyl)propan-2-one
• CAS: 88659-81-8
• 化学式: C₁₀H₁₂O₂
• mdl: MFCD03410477
• 分子量: 164.2
• InChiKey: SGQXQKMSXUGTJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-Hydroxy-1-(4-hydroxy-3-methylphenyl)propan-2-one 生成 1-(4-Hydroxy-3-methylphenyl)propan-2-one
  参考文献：
  名称：

  EHNOMIYA, TAKUDZI;SIRAISI, YASUSI

  摘要：

  DOI：

文献信息

• [EN] ASSAY FOR ENTACTOGENS<br/>[FR] ESSAI D'ENTACTOGENES
  申请人：DADE BEHRING INC

  公开号：WO2005058864A1

  公开（公告）日：2005-06-30

  Methods, compositions and kits are disclosed. The methods are directed to determining the presence of entactogen analytes such as, for example, 3,4­methylenedioxyamphetamine (MDA)3,4-methylenedioxy-methamphetamine (MDMA), 3,4-methylenedioxy-ethylamphetamine (MDEA) and 4-hydroxy-3-methoxy­methamphetamine (HMMA). The method comprises providing in combination in a medium (i) a sample suspected of containing the compound and (ii) an antibody raised against a compound of Formula I that comprises a protein. The medium is examined for the presence a complex comprising the compound and the antibody where the presence of such as complex indicates the presence of the compound in the sample. In one aspect of the above embodiment, the combination further comprises a label conjugate of the compound Formula I.

  揭示了方法、组合物和试剂盒。这些方法旨在确定致幻药物分析物的存在，例如3,4-亚甲二氧苯丙胺（MDA）、3,4-亚甲二氧甲基苯丙胺（MDMA）、3,4-亚甲二氧乙基苯丙胺（MDEA）和4-羟基-3-甲氧基苯丙胺（HMMA）。该方法包括在介质中组合提供（i）疑似含有该化合物的样品和（ii）针对包含蛋白质的化合物的I式的抗体。检查介质是否存在包含该化合物和抗体的复合物，其中这种复合物的存在表明样品中存在该化合物。在上述实施例的一个方面，该组合进一步包括化合物I式的标记结合物。
• NOVEL ESTER DERIVATIVE AND USE THEREOF
  申请人：AMINO YUSUKE

  公开号：US20130053441A1

  公开（公告）日：2013-02-28

  A compound represented by the following formula (I′) wherein X 1 is a methylene group, an ethylene group, a trimethylene group or a vinylene group, X 2 is a divalent group represented by the following formula A or B, Y is an ethylene group or a vinylene group, m and n are each an integer of 0 to 7, which satisfy m+n=0 to 8, R1 and R2 are each independently a hydrogen atom, a methyl group or an ethyl group, provided that when X 1 is a methylene group, then X 2 is not a divalent group represented by the formula A, and when X 1 is a vinylene group, then X 2 is not a divalent group represented by the formula A. The compound is a stable capsinoid derivative, and is useful as an active ingredient of an external blood circulation enhancer or a cosmetic composition, a pharmaceutical composition, or a food composition.

  化合物的化学式如下（I′），其中X1是一个亚甲基基团，乙烯基团，三亚甲基基团或乙烯基基团，X2是由以下公式A或B表示的二价基团，Y是乙烯基团或乙烯基基团，m和n分别为0到7的整数，满足m+n=0到8，R1和R2分别是氢原子，甲基基团或乙基基团，但当X1是亚甲基基团时，X2不是由公式A表示的二价基团，当X1是乙烯基基团时，X2不是由公式A表示的二价基团。该化合物是一种稳定的辣椒素类衍生物，可用作外用血液循环增强剂或化妆品组合物、药用组合物或食品组合物的活性成分。
• Assay for entactogens
  申请人：Zheng Feng Yi

  公开号：US20050130243A1

  公开（公告）日：2005-06-16

  Methods, compositions and kits are disclosed. The methods are directed to determining the presence of entactogen analytes such as, for example, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-methamphetamine (MDMA), 3,4-methylenedioxy-ethylamphetamine (MDEA) and 4-hydroxy-3-methoxy-methamphetamine (HMMA). The method comprises providing in combination in a medium (i) a sample suspected of containing the compound and (ii) an antibody raised against a compound of Formula I that comprises a protein. The medium is examined for the presence a complex comprising the compound and the antibody where the presence of such as complex indicates the presence of the compound in the sample. In one aspect of the above embodiment, the combination further comprises a label conjugate of the compound Formula I.

  本文介绍了方法、组合物和试剂盒。该方法用于确定包括3,4-亚甲二氧苯丙胺（MDA）、3,4-亚甲二氧甲基苯丙胺（MDMA）、3,4-亚甲二氧乙基苯丙胺（MDEA）和4-羟基-3-甲氧基甲基苯丙胺（HMMA）在内的致幻剂分析物的存在。该方法包括在介质中结合（i）怀疑含有该化合物的样品和（ii）针对式I化合物中包含蛋白质的抗体。检查介质中是否存在包含化合物和抗体的复合物，该复合物的存在表示样品中存在该化合物。在上述实施例的一个方面，该组合物还包括化合物式I的标记共轭物。
• EHNOMIYA, TAKUDZI;SIRAISI, YASUSI
  作者：EHNOMIYA, TAKUDZI、SIRAISI, YASUSI

  DOI：——

  日期：——
• ASSAY FOR ENTACTOGENS
  申请人：DADE BEHRING INC.

  公开号：EP1701948A1

  公开（公告）日：2006-09-20